Study evaluation

J. M. Smith and co-workers, "Methyl Methacrylate Subchronic, Chronic and Oncogenic Inhalation Safety Evaluation Studies," Mbstracts of the Eighteenth Mnnual Meeting of the Society of Toxicology, New Orleans, La., 1979. 

The throwaway fuel cycle does not recover the energy values present ia the irradiated fuel. Instead, all of the long-Hved actinides are routed to the final waste repository along with the fission products. Whether or not this is a desirable alternative is determined largely by the scope of the evaluation study. For instance, when only the value of the recovered yellow cake and SWU equivalents are considered, the world market values for these commodities do not fully cover the cost of reprocessing (2). However, when costs attributable to the disposal of large quantities of actinides are considered, the classical fuel cycle has been the choice of virtually all countries except the United States. 

Raina, V. M. et al, "System Modelling Techniques and Insights from the Darlington Proba Evaluation Study," PSA 87 CONF-870820 Vol. 2 TUEV Rhineland. 

Several evaluation studies have been conducted as part of the aft-end igniter development for large solid-motor demonstration programs. However, these results were specific to the particular motor configuration, and no attempt was made to develop a generalized correlation in these programs. 

The list of laboratories or other institutions taking part in the evaluation study... 

Discuss the focus and goals of the evaluation study with the identified evaluation audience (this will include mentees, mentors, managers, the implementation team, etc.). 

Ferreira, I.C.F.R. Calhelha, R.C. Estevinho, L.M.. Queiroz, M.J.R.P. (2004). Screening of antimicrobial activity of diarylamines in the 2,3,5-trimethylbenzo[b]thiophene series a structure-activity evaluation study. Bioorganic Medicinal Chemistry Letters, Vol.l4, No.23, (December 2004), pp. 5831-5833, ISSN 0960-894X... 

Hanvelt et al. (1994) estimated the nationwide indirect costs of mortality due to HIV/AIDS in Canada. A descriptive, population-based economic evaluation study was conducted. Data from Statistics Canada were used, which contained information about aU men aged 25-64 years for whom HIV/AIDS or another selected disease was listed as the underlying cause of death from 1987 to 1991. Based on the human capital approach, the present value of future earnings lost for men was calculated. The estimated total loss from 1987 to 1991 was US 2.11 billion, with an average cost of US 558,000 per death associated with HIV/AIDS. Future production loss due to HIV/AIDS was more than double during the period 1987 to 1991, from US 0.27 to US 0.60 billion. A more comprehensive update of this smdy was presented by Hanvelt et al. (1996). The same database and the same data section but for the calendar years 1987-1993 was used. The indirect cost of future production due to HIV/AIDS in Canada based on the human capital approach for that period was estimated to be US 3.28 billion. The authors also calculated the willingness-to-pay to prevent premature death due to HIV/AIDS, which was estimated based on... 

Lewis DFV, Bird MG, Jacobs MN. Human carcinogens an evaluation study via the COMPACT and HazardExpert procedures. Flum Exper Toxicol 2002 21 115-22. 

Results. Table 7.1 summarizes the results of the evaluation study obtained for CONCORD and CORINA. None of the programs crashed or produced any stereo errors. CORINA had a conversion rate close to 100%, whereas CONCORD converted only 91%. However, CONCORD was faster than CORINA with an average... 

SAFE Saline versus Albumin Fluid Evaluation Study... 

Field Evaluation Studies for Cytolytic/Fungicidal Substances (26). 

Work is in progress to validate the MAE method, proposed for EPA, in a multi-laboratory evaluation study. Nothing similar has been reported for additives in polymeric matrices. Dean el al. [452] have reviewed microwave-assisted solvent extraction in environmental organic analysis. Chee et al. [468] have reported MAE of phthalate esters (DMP, DEP, DAP, DBP, BBP, DEHP) from marine sediments. The focus to date has centred on extractions from solid samples. However, recent experience suggests that MAE may also be important for extractions from liquids. 

Hemandez-Serrato, I.M., Fortoul, I.T., Rojas-Martinez, R., Mendoza-Alvarado, R.L., Canales-Trevino, L., Bochichio-Riccardelli, T., Avila-Costa, R.M., and Olaiz-Fernandez, G., Lead blood concentrations and renal function evaluation Study in an exposed Mexican population, Environmental Research, 100, 227-231, 2006. 

The results of economic evaluation studies should be used as the most relevant information for establishing the initial price of products. 

There is some controversy regarding which method to use in economic evaluation studies to estimate costs and benefits, which has led to attempts at standardization in the field of the economic evaluation of pharmaceuticals. 

This review does not cover pharmaceutical economic evaluation studies, as the Associacion de Economla de la Salud (AES) commissioned a separate review on this subject. 

By means of appropriate thermochemical cycles, it is possible to calculate proton affinities for species for which experimental values are not available. For example, using the procedure illustrated by the two foregoing examples, the proton affinities ofions such as HC03-(g) (1318 k J mol-1) and C032-(g) (2261 kj mol-1) have been evaluated. Studies of this type show that lattice energies are important in determining other chemical data and that the Kapustinskii equation is a very useful tool. 

Lippman ME, Krueger KA, Eckert S et al. (2001) Indicators of lifetime estrogen exposure effect on breast cancer incidence and interaction with Raloxifene therapy in the multiple outcomes of Raloxifene evaluation study participants. J Clin Oncol 19(12) 3111—3116... 

Hendershot, Dennis C., 1992. "Documentation and Utilization of the Results of Hazard Evaluation Studies," prepared for presentation at the AIChE 1992 Spring National Meeting, New Orleans, LA. Rohm and Haas Company, Bristol, PA. 

During the evaluation phase, the various types of existing control measures and their effectiveness are also studied. Control techniques are presented in more detail in section 3-4. During the evaluation study, the likelihood of large and small leaks must be considered. 

Five of the seven respondents who use a matrix also use chemical testing results as a data source. A similar number review the matrix during qualitative hazard evaluation studies (i.e., hazard and operability [HAZOP] studies, what-if, checklist, etc.). 

Most survey respondents indicated that they perform reactive hazard evaluation studies during specific life-cycle phases of a process or product. These phases include process development, commercial process design, periodic re-evaluation, and before proposed modifications. The protocol for hazard evaluation of reactive systems varies from company-to-company. At a minimum, all surveyed companies employ qualitative hazard evaluations.58... 

From the available literature it becomes clear that method evaluation studies do not surpass the level of within-laboratory performances. Although several of these (see Table 3.3.1) reveal satisfactory levels of quality and environmentally relevant limits of detection, a genuine quality assurance of these methods is still lacking. There are no reports of interlaboratory studies and certified reference materials for surfactants are not available on the market yet. It can therefore be concluded that there remains much to be done in the field of improving and evaluating quality of analytical measurements of surfactants in biota. 

Flosequinan has a positive inotropic effect and shows a tendency to increase the heart rate, atrioventricular conduction in patients with atrial fibrillation and neurohormonal activation. Although the precise mechanisms involved have remained unclear up to now [29], this drug has been used to treat congestive heart failure (CHF). The FDA approved flosequinan (Manoplax) in 1993. However, the drug was withdrawn a year later because the PROFILE (prospective randomized flosequinan longevity evaluation) study indicated that flosequinan had adverse effects on survival, and that beneficial effects on the symptoms of heart failure did not last beyond the first 3 months of therapy, after which patients on the dmg had a higher rate of hospitalization than patients taking a placebo [14]. 

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