Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Epidermal growth factor family

Higashiyama S, Horikawa M, Yamada K, Ichino N, Nakano N, et al. 1997. A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4. J Biochem 122 675-680. [Pg.261]

Tolgay Ocal I, Doiled-Filhart M, D Aquila TG, et al. Tissue microarray-based studies of patients with lymph node negative breast carcinoma show that met expression is associated with worse outcome but is not correlated with epidermal growth factor family receptors. Cancer 2003 97 1841-48. [Pg.794]

Trastuzumab (Herceptin) is a humanized monoclonal antibody against the HER2/neu (ErbB-2) member of the epidermal growth factor family of cellular receptors. The internal domain of the HER2/neu glycoprotein encodes a tyrosine kinase that activates downstream signals and enhances metastatic potential and inhibits apoptosis. HER2/neu is overexpressed in up to 30% of breast cancers and is associated with clinical resistance to cytotoxic and hormone therapy. A number of mechanisms of action have... [Pg.701]

Betacellulin (BTC), a member of the epidermal growth factor family purified from mouse beta tumor cells (betaTC-3). BTC can bind receptor tyrosine kinase, EGF receptor (ErbBl) and ErbB4. Besides other actions, a critical involvement of BTC in vascular remodeling has been reported [J. Miyagawa et al., Endocr. J. 1999, 46, 755 ... [Pg.46]

ECF family, epidermal growth factor family, a member of the gastroenteropancreatic peptide families. This family comprises... [Pg.115]

Epidermal Growth Factor Receptor Family Growth Factors... [Pg.482]

Epidermal Growth Factor (EGF) Receptor Family Epidermal Growth Factor Receptor 2 (ErbB2) Epidural (Space)... [Pg.1491]

Kane, S. 2006. Cancer therapies targeted to the epidermal growth factor receptor and its family members. Expert Opinion on Therapeutic Patents 16(2), 147-164. [Pg.289]

Anthelmintic, antiprotozoal, anti-neoplastic, and antiviral agent Binds many proteins, i.e., cytokines. epidermal growth factor, and members of the FGF family inhibits dengue virus infec-tivity of host cells very long in vivo half-life, exhibits a wide range of toxic side effects 40-47... [Pg.286]

Sartor CL Biological modifiers as potential radiosensitizers targeting the epidermal growth factor receptor family. Semin Oncol 2000 27(6 Suppl 11) 15-20. [Pg.22]

Montgomery RB, Guzman J, O Rourke DM, Stahl WL. Expression of oncogenic epidermal growth factor receptor family kinases induces paclitaxel resistance and alters beta-tubulin isotype expression. J Biol Chem 2000 275 17,358-17,363. [Pg.250]

Fry DW. Inhibition of the epidermal growth factor receptor family of tyrosine kinases as an approach to cancer chemotherapy progression from reversible to irreversible inhibitors. Pharmacol Ther 1999 82 207-218. [Pg.334]

Receptor Tyrosine Kinases and Their Role in Malignancy Targeting the Epidermal Growth Factor Receptor Family Clinical Trials with Anti-HER-2 Strategies Clinical Trials Targeting the EGFR (HER-1)... [Pg.339]

TARGETING THE EPIDERMAL GROWTH FACTOR RECEPTOR FAMILY... [Pg.340]

See other pages where Epidermal growth factor family is mentioned: [Pg.227]    [Pg.222]    [Pg.515]    [Pg.123]    [Pg.177]    [Pg.227]    [Pg.222]    [Pg.515]    [Pg.123]    [Pg.177]    [Pg.281]    [Pg.478]    [Pg.478]    [Pg.565]    [Pg.706]    [Pg.709]    [Pg.1192]    [Pg.1254]    [Pg.1258]    [Pg.223]    [Pg.93]    [Pg.27]    [Pg.419]    [Pg.481]    [Pg.267]    [Pg.506]    [Pg.230]    [Pg.66]    [Pg.166]    [Pg.113]    [Pg.308]    [Pg.342]    [Pg.54]    [Pg.99]    [Pg.169]    [Pg.86]    [Pg.17]    [Pg.325]    [Pg.327]   
See also in sourсe #XX -- [ Pg.184 ]



SEARCH



Epidermal

Epidermal growth factor

Epidermal growth factor receptor family

Epidermal growth factor receptor family targeting

Growth Factor Families

© 2024 chempedia.info