Bacterial enhancers

Systemic antibiotics are indicated for moderate-severe inflammatory acne not responding to topical treatments. Systemic antibiotics act on 1) suppression of P. acnes growth 2) inhibition of bacterial lipases 3) reduction of free fatty acids and 4) reduction of inflammation. Oxytetracycline and its derivatives are the most commonly used oral antibiotics. Second-generation tetracyclines such as minocycline, doxy-cycline and lymecycline present longer half-lives, enhanced bacterial activity and lower... 

IgG Main antibody in the secondary response. Opsonizes bacteria, making them easier to phagocytose. Fixes complement, which enhances bacterial killing. Neutralizes bacterial toxins and viruses. Crosses the placenta. 

Song, ZJ. et al., Ginseng treatment enhances bacterial clearance and decreases lung pathology in athymic rats with chronic P. aeruginosa pneumonia, Apmis, 105, 438, 1997. 

Li L, Steffens JC. 2002. Overexpression of polyphenol oxidase in transgenic tomato plants results in enhanced bacterial disease resistance. Planta 215 239-247. 

Lindell, M. J., W. Graneli, and L. J. Tranvik. 1995. Enhanced bacterial growth in response to... 

Rolls, J. K., Lei, D., Nelson, S., Summer, W. R. and Shellito, J. E. (1997). Pulmonary cytokine gene therapy. Adenoviral-mediated murine interferon gene transfer compartmentally activates alveolar macrophages and enhances bacterial clearance. Chest 111, 104S. 

ER. Neutrophils from patients with heterozygous germline mutations in the von Hippel Lindau protein (pVHL) display delayed apoptosis and enhanced bacterial phagocytosis. Blood 2006 108 3176-3178. 

Enhanced bacterial growth rate and increased rate of n-alkane consumption Surfactant solubilization increases aqueous solubility of hydrocarbon 24... 

This chapter describes dental caries (tooth decay) and its causes. Sucrose and other mono- and disaccharides are metabolized to acid (lactate) by bacteria that remain in stagnation areas of the teeth. Rats and hamsters fed a 50% sucrose diet developed a caries-sensitive, predominantly gram-positive microbiota that became caries resistant when the rodents were fed penicillin (Sect. 1). Further studies identified Streptococcus mutans (S. mutans) as the etiological agent. This organism synthesizes an insoluble polysaccharide capsule that is stable and retains lactate at the enamel surface (Sect. 2). The key enzyme, glucosyl transferase, is related to salivary amylase which adheres to oral bacteria and enhances bacterial acid production. The chapter concludes with a discussion of salivary and other factors responsible for the marked variation observed in individual caries experience (Sect. 3). 

Luminous bacteria are bioluminescent microorganisms whose luciferase genes (lux), proteins and intact cells are widely used in applied research and commercial products. Acknowledging the commercial value of luminescent cells also in entertainment and education, we have conducted research on luminous bacteria from marine samples and have isolated Photobacterium phosphoreum (strain RL-1) from coastal marine sediment. In order to maximize the luminescence activity of RL-1, we examined a series of extracts prepared from dried marine foodstuff. Because chitinous compounds and some amino acids are known to be abundant in dried squid and shrimp, we also tested the effects of those compounds on the luminescence activity. Among the supplemental compounds tested, chitosan, cysteine, and aspartic acid were found to enhance the luminescence activity of RL-1. The present results indicate that some amino acids and chitinous compounds are effective supplements for further enhancing bacterial light production in an enriched medium (SWC ). 

Lahteenmaki, K., Virkola, R., Saren, A., Emody, L., Korhonen, T.K. 1998. Expression of plasminogen activator pla of Yersinia pestis enhances bacterial attachment to the mammalian extracellular matrix. Infect. Immun. 66 5755-5762. 

Brodsky, I.E., Medzhitov, R. 2008. Reduced secretion of YopJby Yersinia limits in vivo cell death but enhances bacterial virulence. PLoS Pathog. 4 el000067. 

This was by far the greatest crisis the earth has ever endured. Many kinds of microbes were immediately wiped out. Microbial life had no defence against this cataclysm except the standard way of DNA replication and duplication, gene transfer and mutation. From multiple deaths and an enhanced bacterial sexuality that is characteristic of bacteria exposed to toxins came a reorganisation of the superorganism we call the microcosm. The newly resistant bacteria multiplied, and quickly replaced those sensitive to oxygen on the Earth s surface as other bacteria survived beneath them in the anaerobic layers of mud and soil. From a holocaust that rivals the nuclear one we fear today came one of the most spectacular and important revolutions in the history of life. 

Accelerated thermogenesis—The nutrients provided by the supplements act as a "supercharger" for the microbial populations. Consequently their increased activity generates more heat. Specifically, supplementation with vegetable oil (cottonseed oil) increased populations of actinomycetes and thermophilic fungi (Schisler and Patton, 1 970) while soluble carbohydrates (molasses) enhanced bacterial populations (Hayes and Randle. 1968). 

Olszanowski A, Piechowiak K. (2006).The use of an electric field to enhance bacterial movement and hydrocarbon biodegradation in soils. Polish Journal of Environmental Studies 15(2) 303-309. 

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