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Endocannabinoids signaling

Based on the role of endocannabinoids and cannabinoid receptors in several pathological conditions, the pharmacological manipulation of their levels or action is being developed as a therapeutic strategy. Enhancement of endocannabinoid signalling when this plays uniquely a protective role can be effected in a safer way using (i) cannabis extracts in which the presence of non-psychotropic cannabinoids with therapeutic activity per... [Pg.468]

Piomelli, D. The molecular logic of endocannabinoid signaling. Nature Rev. Neurosci. 4 873-884, 2003. [Pg.926]

Wilson RI, Nicoll RA Endocannabinoid signaling in the brain. Science 2002 296 678. [PMID 11976437]... [Pg.466]

Basavarajappa BS The endocannabinoid signaling system A potential target for next-generation therapeutics for alcoholism. Mini Rev Med Chem 2007 7 769. [PMID 17692039]... [Pg.506]

Retrograde Endocannabinoid Signaling in Short-Term Synaptic Depression.447... [Pg.435]

Azad SC, Monory K, Marsicano G, Cravatt BF, Lutz B, Zieglgansberger W, Rammes G (2004) Circuitry for associative plasticity in the amygdala involves endocannabinoid signaling. J Neurosci 24(44) 9953-61... [Pg.466]

A, Paul P, Gangadharan U, Hobbs C, Di Marzo V, Doherty P (2003) Cloning of the first sn 1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signalling in the brain. J Cell Biol 163 463-8... [Pg.467]

Bodor AL, Katona I, Nyiri G, Mackie K, Ledent C, Hajos N, Freund TF (2005) Endocannabinoid signaling in rat somatosensory cortex laminar differences and involvement of specific intemeuron types. J Neurosci 25 6845-56... [Pg.467]

Kreitzer AC, Malenka RC (2005) Dopamine modulation of state-dependent endocannabinoid release and long-term depression in the striatum. J Neurosci 25(45) 10537—45 Kreitzer AC, Regehr WG (2001) Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto purkinje cells. Neuron 29 717-27 Kreitzer AC, Carter AG, Regehr WG (2002) Inhibition of interneuron firing extends the spread of endocannabinoid signaling in the cerebellum. Neuron 34 787-96... [Pg.471]

Trettel J, Levine ES (2003) Endocannabinoids mediate rapid retrograde signaling at intemeuron-pyramidal neuron synapses of the neocortex. J Neurophysiol 89 2334-8 Trettel J, Fortin DA, Levine ES (2004) Endocannabinoid signalling selectively targets perisomatic inhibitory inputs to pyramidal neurones in juvenile mouse neocortex. J Physiol 556(Pt 1) 95-107... [Pg.476]

Tsou K, Brown S, Sanudo-Pena MC, Mackie K, Walker JM (1997) Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neurosci 83(2) 393 411 Van Beugen BJ, Nagaraja RY, Hansel C (2006) Climbing fiber-evoked endocannabinoid signaling heterosynaptically suppresses presynaptic cerebellar long-term potentiation. J Neurosci 26(32) 8289-94... [Pg.476]

Wilson RI, Kunos G. Nicoll RA (2001) Presynaptic specificity of endocannabinoid signaling in the hippocampus. Neuron 31(3) 453-62... [Pg.478]

Yin HH, Lovinger DM (2006) Frequency-specific and D2 receptor-mediated inhibition of glutamate release by retrograde endocannabinoid signaling. Proc Natl Acad Sci USA 103(21) 8251-6... [Pg.478]

Zhu PJ, Lovinger DM (2005) Retrograde endocannabinoid signaling in a postsynaptic neu-ron/synaptic bouton preparation from basolateral amygdala. J Neurosci 25(26) 6199-6207... [Pg.478]

Harkany T, Guzman M, Galve-Ropert I, Berghuis P, Devi LA, Mackie K (2007) The emerging functions of endocannabinoid signaling during CNS development Trends Pharmacol Sci... [Pg.571]

Most of the analytical approaches do not take into account the topological distribution of 2-AG in tissues, often missing out on critical information about the endocannabinoid signaling. For example, a physiological analysis of the... [Pg.48]

Ahn, K., McKinney, M., and Cravatt, B. (2008). Enzymatic pathways that regulate endocannabinoid signaling in the nervous system. Chem. Rea. 108, 1687-1707. [Pg.51]

Paria, B. C., Wang, H., and Dey, S. K. (2002). Endocannabinoid signaling in synchronizing embryo development and uterine receptivity for implantation. Chem. Phys. lipids 121, 201—210. [Pg.132]

INVOLVEMENT OF ENDOCANNABINOID SIGNALING IN THE NEUROPROTECTIVE EFFECTS OF SUBTYPE 1 METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS IN MODELS OF CEREBRAL... [Pg.337]

Bodor, A. L., Katona, I., Nyiri, G., Mackie, K., Ledent, C., Hajos, N., and Freund, T. F. (2005). Endocannabinoid signaling in rat somatosensory cortex Laminar differences and involvement of specific interneuron types. J. Neurosci. 25, 6845-6856. [Pg.347]

Chen, K., Neu, A., Howard, A. L., Foldy, C., Echegoyen, J., Hilgenberg, L., Smith, M., Mackie, K., and Soltesz, I. (2007). Prevention of plasticity of endocannabinoid signaling inhibits persistent limbic hyperexcitability caused by developmental seizures. J. Neurosci. 27, 46—58. [Pg.348]

See other pages where Endocannabinoids signaling is mentioned: [Pg.909]    [Pg.590]    [Pg.231]    [Pg.285]    [Pg.137]    [Pg.447]    [Pg.449]    [Pg.455]    [Pg.469]    [Pg.470]    [Pg.470]    [Pg.36]    [Pg.37]    [Pg.40]    [Pg.40]    [Pg.52]    [Pg.53]    [Pg.54]    [Pg.67]    [Pg.68]    [Pg.70]    [Pg.120]    [Pg.120]    [Pg.132]    [Pg.909]   
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See also in sourсe #XX -- [ Pg.366 , Pg.383 ]

See also in sourсe #XX -- [ Pg.469 , Pg.470 ]



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Endocannabinoids

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