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Medication-drug interaction

Trazodone has relatively few drug interactions. Medications that induce or inhibit first-pass metabolism may affect trazodone s plasma concentration. Even though trazodone is commonly used for SSRI-induced insomnia, it may be counter productive. Compounds such as... [Pg.301]

Please outline any concomitant medications that are permitted for the duration of the trial. If the medicinal product (s) is currently licensed it is recommended that the current summary of producf characteristics (Previously known as the data sheet) is consulted for information on potential drug interactions. [Pg.83]

However, pervasive computing will ultimately do much more it will change the very way in which new drugs are tested. At present, all drugs go through three clinical phases, but the process is both very costly and very inefficient. Clinical trials cannot detect rare side effects and drug interactions, or sometimes even fairly common reactions. In fact, one recent study conducted by Harvard Medical School and Public Citizen, the US consumer advocacy... [Pg.768]

Review medication profile for drug-drug interactions (extensive lists may be found at www.drug-interactions.com)... [Pg.43]

Review medication profile daily for drug-drug interactions... [Pg.65]

Interview the patient to assess complementary or alternative medication use. Counsel appropriately based on indications and drug interactions. [Pg.104]

Evaluate the patient s medical record and medication history, and conduct a patient interview to assess for the presence of drug allergies, adverse drug reactions, and drug interactions. [Pg.104]

Provide patient education with regard to CAD, Ml, indications for medications, and potential adverse effects and drug interactions. [Pg.104]

Inform the patient about the potential drug-drug interactions with warfarin, including over-the-counter medications and dietary supplements (Tables 7-8, 7-9, and 7-10). Instruct the patient to call the health care practitioner responsible for monitoring warfarin therapy before starting any new medications or dietary supplements. [Pg.158]

Use of zileuton is uncommon due to the need for dosing four times a day, potential drug interactions, and the potential for hepatotoxicity with the resulting need for frequent monitoring of liver enzymes. In patients started on zileuton, serum alanine aminotransferase concentrations should be monitored before treatment begins, monthly for the first 3 months, every 2 to 3 months for the remainder of the first year, and then periodically thereafter for as long as the patient continues to receive the medication. Zileuton also inhibits the cytochrome P-450 (CYP) mixed function enzyme system and has been shown to decrease the clearance of theophylline, R-warfarin and propranolol.34... [Pg.222]

Theophylline is a non-specific phosphodiesterase inhibitor that increases intracellular cAMP within airway smooth muscle resulting in bronchodilation. It has a modest bronchodila-tor effect in patients with COPD, and its use is limited due to a narrow therapeutic index, multiple drug interactions, and adverse effects. Theophylline should be reserved for patients who cannot use inhaled medications or who remain symptomatic despite appropriate use of inhaled bronchodilators. [Pg.238]

Evaluate the medication regimen for drug interactions, adverse reactions, and allergies. [Pg.255]

Monitor for adverse drug reactions, drug-drug interactions, and compliance with the therapeutic regimen initially and any time there is a change in symptoms or medications. [Pg.266]

Assess for potential drug interactions whenever there is a change in the patient s medications, particularly for patients taking cimetidine, omeprazole, or sucralfate. [Pg.279]

Develop a treatment plan with the patient and other health care professionals if appropriate. Choose therapeutic options based on the underlying cause of nausea and vomiting, duration and severity of symptoms, comor-bid conditions, medication allergies, presence of contraindications, risk of drug-drug interactions, and treatment adverse-effect profiles. [Pg.305]

Mechanisms of action, effectiveness for specific seizure types, common adverse effects, and potential for drug interactions are key elements in selecting medications for individual patients. [Pg.443]

Frequently monitor the patient for signs of drug toxicity and seizures until the patient s drug concentrations have stabilized. Drug interactions are likely when patients are on more than one AED therefore, closely evaluate the patient s entire medication profile, and change medications or doses to minimize the interaction, if possible. [Pg.470]

Determine whether there are any drug interactions with the patient s current or home medication regimens. Do you need to adjust the dose of any medications for toxic or subtherapeutic concentrations from the drug interaction ... [Pg.470]

The major drug interactions of antidepressants are shown in Table 35—6.9,19,30 Antidepressants cause both pharmacodynamic (e.g., additive pharmacologic effects) and pharmacokinetic (e.g., changes in drug levels) interactions with other medications. [Pg.575]

Each antidepressant has a response rate of approximately 60% to 80%, and no antidepressant medication or class has been reliably shown to be more efficacious than another 22 MAOIs may be the most effective therapy for atypical depression, but MAOI use continues to wane because of problematic adverse effects, dietary restrictions, and possibility of fatal drug interactions.22,28 There is some evidence that dual-action antidepressants, such as TCAs and SNRIs, may be more effective for inpatients with severe depression than are the single-action drugs such as SSRIs,22,28 but the more general assertion that multiple mechanisms of action confer efficacy advantages is quite controversial.33... [Pg.578]

Review the patient s medication profile to ensure that there are no potential/actual pharmacotherapy problems related to dosing, disease-state precautions or contraindications, drug-drug interactions, unnecessary therapeutic duplication, etc. [Pg.582]

Treatment of elderly patients with bipolar disorder requires special care because of increased risks associated with concurrent non-psychiatric medical conditions and drug-drug interactions. General medical conditions including endocrine,... [Pg.601]

Vigilance for drug-drug interactions is required because of the greater number of medications prescribed to elderly patients and enhanced sensitivity to adverse effects. Pharmacokinetic interactions include metabolic enzyme induction or inhibition and protein binding displacement interactions (e.g., divalproex and warfarin). Pharmacodynamic interactions include additive sedation and cognitive toxicity, which increases risk of falls and other impairments. [Pg.602]

It is important to review patient medication profiles for drugs that may aggravate sleep disorders. Patients should be monitored for adverse drug reactions, potential drug-drug interactions, and adherence to their therapeutic regimens. [Pg.621]

Are there any medication problems, including presence of adverse drug reactions, drug allergies, and drug interactions ... [Pg.665]

A thorough medical history with emphasis on cardiac disease must be taken before starting any treatment for ED to assess for ability to safely perform sexual activity and to assess for possible drug interactions. [Pg.779]

Check the patient profile and talk with the patient to ensure that there are no significant drug interactions with other concurrent medications and therapies. [Pg.958]


See other pages where Medication-drug interaction is mentioned: [Pg.78]    [Pg.10]    [Pg.45]    [Pg.665]    [Pg.271]    [Pg.5]    [Pg.79]    [Pg.80]    [Pg.150]    [Pg.189]    [Pg.263]    [Pg.458]    [Pg.470]    [Pg.480]    [Pg.532]    [Pg.564]    [Pg.564]    [Pg.573]    [Pg.578]    [Pg.630]    [Pg.781]    [Pg.786]    [Pg.792]    [Pg.1028]   


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Medication interaction

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