Desquamative interstitial pneumonia

Freed JA, Miller A, Gordon RE, et al. 1991. Desquamative interstitial pneumonia associated with chrysotile asbestos fibers. Br J Ind Med 48(5) 332-337. 

Bone RC, Wolfe J, Sobonya RE, Kerby GR, Stechschulte D, Ruth WE, Welch M. Desquamative interstitial pneumonia following long-term nitrofurantoin therapy. Am J Med 1976 60(5) 697-701. 

Respiratory Bronchiolitis-Associated Interstitial Lung Disease 341 Desquamative Interstitial Pneumonia 341 Lymphoid Interstitial Pneumonia 342 Acute Interstitial Pneumonia 342 Sarcoidosis 343 Miscellaneous Rare Forms of Interstitial Lung Disease of Unknown Etiology 345 Pulmonary Langerhans Cell Histiocytosis 345 Lymphangioleiomyomatosis 345 Eosinophilic Pneumonia 346 Pulmonary Alveolar Proteinosis 348 Pulmonary Microlithiasis 348... 

The term idiopathic interstitial pneumonias refers to a group of seven entities with distinct histologic patterns idiopathic pulmonary fibrosis (IFF), characterized by the pattern of usual interstitial pneumonia (UIP) nonspecific interstitial pneumonia (NSIP) cryptogenic organizing pneumonia (COP) respiratory bron-chiohtis-associated interstitial lung disease (RB-ILD) desquamative interstitial pneumonia (DIP) lymphoid interstitial pneumonia (LIP) and acute interstitial pneumonia (AIP). 

Akira M, Yamamoto S etal. (1997) Serial computed tomographic evaluation in desquamative interstitial pneumonia. Thorax 52 333-337... 

Idiopathic pulmonary fibrosis Nonspecific interstitial pneumonia Cryptogenic organizing pneumonia Desquamative interstitial pneumonia Respiratory bronchioUtis-associated interstitial lung disease Lymphocytic interstitial pneumonia Acnte interstitial pnemnonia... 

Usual interstitial pneumonia Nonspecific interstitial pneumonia Organizing pneumonia Diffuse alveolar damage Respiratory bronchiolitis Desquamative interstitial pneumonia Lymphocytic interstitial pneumonia Idiopathic pulmonary fibrosis/cryptogenic fibrosing alveolitis Nonspecific interstitial pneumonia (provisional) Cryptogenic organizing pneumonia Acute interstitial pneumonia Respiratory bronchiolitis-associated interstitial lung disease Desquamative interstitial pneumonia Lymphocytic interstitial pneumonia... 

Figure 5 HRCT images demonstrating prominent ground glass opacities without architectural distortion in a patient with DIP. Abbreviations HRCT, high-resolution computed tomography DIP, desquamative interstitial pneumonia.

Abbreviations. DIP, desquamative interstitial pneumonia RB-ILD, respiratory bronchiolitis-associated interstitial lung disease GGO, ground glass opacities. Source. Adapted from Refs. 31, 34, and 39. 

Ryu JH, Myers JL, Capizzi SA, et al. Desquamative interstitial pneumonia and respiratory bronchiohtis-associated interstitial lung disease. Chest 2005 127(1) 178-184. 

Hartman TE, Primack SL, Swensen SJ, et al. Desquamative interstitial pneumonia thin-section CT findings in 22 patients. Radiology 1993 187(3) 787-790. 

Heyneman LE, Ward S, Lynch DA, et al. Respiratory bronchiolitis, respiratory bronchiolitis-associated interstitial lung disease, and desquamative interstitial pneumonia different entities or part of the spectrum of the same disease process AJR Am J Roentgenol 1999 173(6) 1617-1622. 

Hartman TE, Primack SL, Kang EY, et al. Disease progression in usual interstitial pneumonia compared with desquamative interstitial pneumonia. Assessment with serial CT. Chest 1996 110(2) 378-382. 

Yousem SA, Colby TV, Gaensler EA. Respiratory bronchiohtis-associated interstitial lung disease and its relationship to desquamative interstitial pneumonia. Mayo Clin Proc 1989 64(11) 1373-1380. 

Vassallo R, Jensen EA, Colby TV, et al. The overlap between respiratory bronchiolitis and desquamative interstitial pneumonia in pulmonary Langerhans cell histiocytosis high-resolution CT, histologic, and functional correlations. Chest 2003 124(4) 1199-1205. 

H. Desquamative Interstitial Pneumonia/Respiratory Bronchiolitis Interstitial Lung Disease... 

Desquamative interstitial pneumonia (DIP) and RBILD are clinicopathologic entities that occur mostly in current or former smokers (3,8,65,67,69-71). Because of their overlapping clinical features, pathogenesis, and histopathologic findings, most authorities regard these two entities as representing different ends of a spectrum of the same disease process (8,65,70,72,73). 

Travis WD, Matsui K, Moss J, et al. Idiopathic nonspecific interstitial pneumonia prognostic significance of cellular and fibrosing patterns survival comparison with usual interstitial pneumonia and desquamative interstitial pneumonia. Am J Surg Pathol 2000 24 19-33. 

Carrington CB, Gaensler EA, Coutu RE, et al. Natural history and treated course of usual and desquamative interstitial pneumonia. N Engl J Med 1978 298 801-809. Brown CH, Tumer-Warwick M. The treatment of cryptogenic fibrosing alveolitis... 

Respiratory Bronchiolitis-Associated Interstitial Lung Disease (RB-ILD) and Desquamative Interstitial Pneumonia (DIP)... 

Figure 2 High-resolution chest CT of desquamative interstitial pneumonia in a 58-year-old smoker. Extensive areas of ground-glass opacities are present hilateraUy.

Figure 3 Histopathology of desquamative interstitial pneumonia (DIP). Alveolar spaces are filled with pigmented macrophages.

Craig PJ, Wells AU, Doffman S, et al. Desquamative interstitial pneumonia, respiratory bronchiolitis and their relationship to smoking. Histopathology 2004 45 275-282. 

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