Acute interstitial pneumonia pathology

Silva Cl, Churg A, Muller NL. Hypersensitivity pneumonitis spectrum of high-resolution CT and pathologic findings. AJR Am J Roentgenol 2007 188 334-344. Vourlekis JS. Acute interstitial pneumonia. Clin Chest Med 2004 25 739-747. Bouros D, Nicholson AC, Polychronopoulos V, et al. Acute interstitial pneumonia. Eur Respir J 2000 15 412 18. 

Ichikado K, Johkoh T, Ikezoe J, et al. Acute interstitial pneumonia high-resolution CT findings correlated with pathology. AJR Am J Roentgenol 1997 168(2) 333-338. 

Sometimes HP has the pathological characteristics of NSIP (Fig. 13.11). The patients with desquamative interstitial pneumonia have often widespread ground-glass opacity indistinguishable from some cases of acute or subacute HP (Lynch et al. 1995). 

Research studying the results of airway clearance is often difficult to evaluate because the components of a given treatment have not been standardized. Availability of equipment or education about a technique, as well as cultural differences in its application, confound the results. CPT does not appear to benefit patients during recovery from acute exacerbations of COPD or pneumonia. These conditions are characterized by interstitial pathology, which cannot be influenced by physical interventions in the airways (16,22,49). Further studies are needed to identify the patients, and more circumstances, who are at risk from complications or adverse effects of CPT. 

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