Cigarettes initiation

Calcium Hypochlorite. High assay calcium hypochlorite [7778-54-3] was first commercialized in the United States in 1928 by Mathieson Alkali Works, Inc. (now Olin Corp.) under the trade name HTH. It is now produced by two additional manufacturers in North America (Table 5). Historically, it usually contained about 1% water and 70—74% av CI2, so-called anhydrous product, but in 1970, a hydrated product was introduced (234). It is similar in composition to anhydrous Ca(OCl)2 except for its higher water content of about 6—12% and a slightly lower available chlorine content. This product has improved resistance to accidental initiation of self-sustained decomposition by a Ht match, a Ht cigarette, or a small amount of organic contamination. U.S. production in the 1990s consists primarily of partially hydrated Ca(OCl)2, which is sold as a 65% av CI2 product mainly for swimming pool use. Calcium hypochlorite is also sold as a 50% av CI2 product as a sanitizer used by dairy and food industries and in the home, and as a 32% product for mildew control. 

The ignition temperature is the minimum temperature required to initiate or cause self-sustained combustion. Table 2 also Hsts ignition temperatures of several common ethers. Attention is directed to the particularly low ignition temperature of ethyl ether, especially with reference to some common ignition sources such as a lighted cigarette (732°C) or a pressurized (0.7 MPa or 100 psi) steam line (180°C). 

Nicotine is the main psychoactive ingredient of tobacco and is responsible for the stimulant effects and abuse/ addiction that may result form tobacco use. Cigarette smoking rapidly (in about 3 sec ) delivers pulses of nicotine into the bloodstream. Its initial effects are caused by its activation of nicotinic acetylcholine (nACh) receptors. nACh receptors are ligand-gated ion-channels and pre- and postsynaptically located. Reinforcement depends on an intact mesolimbic dopamine system (VTA). nACh receptors on VTA dopamine neurons are normally activated by cholinergic innervation from the laterodorsal tegmental nucleus or the pedunculopontine nucleus. 

All patients should be treated for acute attacks and maintained on prophylactic treatment for 6 to 12 months after the initial episode. Aggravating factors such as alcohol or cocaine use and cigarette smoking should be stopped. 

Water-soluble nickel salts enter the cells with relative ease but are less effective than crystalline particulates in the cell transformation assay, when using hamster cells [429, 430]. However, an enhancement of viral transformation of cells has been found [431, 432], In addition, a synergistic effect of cigarette smoke extracts, benzo[a]pyrene and nickel sulphate on the morphological transformation of hamster embryo cells has also been obtained [433], It was suggested that nickel salts are more potent as promoters than they are as initiators [434],... 

Galliant and Schubert (2007) 13 16 9 NR 15.1 Glu in hippocampus or ACC did not differ between groups. In current smokers, number of cigarettes per day, pack-years, age of smoking initiation did not correlate with Glu. 

Milberger S, Biederman J, Faraone SV, Chen L, Jones J (1997) ADHD is associated with early initiation of cigarette smoking in children and adolescents, J Am Acad ChUd Adolesc Psychiatry 36(1) 37 4... 

Wayne GF, Connolly GN (2002) How cigarette design can affect youth initiation into smoking camel cigarettes 1983-93, Tob Control 11 132-139... 

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