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Chitosan wound healing

Chitosan acetate and lactate salt films have been tested as wound-healing materials. Mechanical, bioadhesive and biological evaluation of the films were carried out. The results were compared to Omiderm . Chitosan lactate exhibited a lower tensile strength, however, it was more flexible and bioadhesive than chitosan acetate. Chitosan lactate and Omiderm did not cause any allergic reactions in contrast, chitosan acetate produced skin irritation clearly due to the anion. Nevertheless, no sign of toxicity was encountered when the extracts of three preparations were administered parenterally [244]. [Pg.185]

More recently chitosan polymers which are derivatives of chitin materials have evoked interest due to their bioactivity and biodegradability. For example, N-carboxybutyl chitosan has been show to effectively promote wound healing (9). Acetate, and butyrate derivatives of chitosan have decreased blood clotting time significantly (10). [Pg.11]

Shigemasa, Y. (1993). Effects of chitosan on wound healing. In "Carbohydrates and... [Pg.118]

Ueno, H., Mori, T., and Fujinaga, T. (2001). Topical formulations and wound healing applications of chitosan. Adv. Drug Deliv. Rev. 52,105-115. [Pg.136]

For other polysaccharides such as chitosan a high antimicrobial activity has been described - mainly against Escherichia coli and Staphylococcus aureus [153,154]. This activity of chitosan is the basis for the development of materials for wound healing, e.g., in combination with N,0-(carboxymethyl)chitosan and collagen [155]. [Pg.83]

Wound healing - High degree of deacetylation (DD) chitosan preferred over chitin - Low molecular weight samples (oligomers)... [Pg.99]

Altman et al. utilized a composite silk fibroin/chitosan scaffold for seeding and in vivo delivery of human ADSCs in a murine cutaneous wound model, and the delivery technique conferred physiological benefits to accelerated wound closure. ADSC seeded on a silk fibroin/chitosan scaffold differentiated into fibrovascular, endothelial, and epithelial components of restored tissue and enhanced the wound healing process [219]. [Pg.52]

Grafted chitosans have great utility in controlled drug release [115], tissue engineering [116], wound-healing [117] and cardiovascular applications [118-119]. Moreover, there are several reports regarding the use of enzymes in polymer s)m-thesis and modification [120-121]. In fact, enz)mies offer the potential advantage... [Pg.141]

The rapid healing of wounds is desirable for patients, especially those suffering from diabetes, because they show an extremely slow rate of healing. Chitin and chitosan have been investigated by many researchers for a long time as possible wound-healing accelerators [143,144]. Chitin and its derivatives can be applied safely to animals, as well as the humans. [Pg.145]

Minagawa T, Okamura Y et al (2007) Effects of molecular weight and deacetylation degree of chitin/chitosan on wound healing. Carbohydr Polym 67 640-644... [Pg.38]

Sung JH, Hwang MR et al (2010) Gel characterisation and in vivo evaluation of minocycline-loaded wound dressing with enhanced wound healing using polyvinyl alcohol and chitosan. Int J Pharm 392 232-40... [Pg.43]

Wound healing rate of the PDLLA/ Du et al. chitosan group was higher than in [134] the other groups. PDLLA/chitosan promoted wound healing of alkali-burned corneas in vivo and also decreased scar tissue formation... [Pg.69]

ArchanaD, Dutta J, Dutta PK (2010) Chitosan-pectin-titanium dioxide nano-composite film an investigation for wound healing applications. Asian Chitin J 6 45-46... [Pg.74]

Sathirakul K, How NC, Stevens WF et al (1996) Application of chitin and chitosan bandages for wound-healing. In Domard A, Jeauniaux C, Muzzarelli R, Roberts G (eds) Proceedings of the first international conference of the European Chitin Society. Advances in chitin science, vol 1. Jacques Andre Fhiblisher, Lyon... [Pg.75]

See other pages where Chitosan wound healing is mentioned: [Pg.152]    [Pg.152]    [Pg.152]    [Pg.193]    [Pg.193]    [Pg.194]    [Pg.199]    [Pg.74]    [Pg.479]    [Pg.495]    [Pg.278]    [Pg.357]    [Pg.108]    [Pg.111]    [Pg.162]    [Pg.473]    [Pg.159]    [Pg.172]    [Pg.171]    [Pg.96]    [Pg.97]    [Pg.175]    [Pg.113]    [Pg.224]    [Pg.231]    [Pg.232]    [Pg.94]    [Pg.114]    [Pg.114]    [Pg.115]    [Pg.118]    [Pg.146]    [Pg.146]    [Pg.147]    [Pg.140]    [Pg.35]    [Pg.52]    [Pg.53]   
See also in sourсe #XX -- [ Pg.22 ]



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