Chemicals dimethylformamide

The idea is to have everything in place before the oxygen is applied. So, lOOg of safrole is in the addition funnel and stirring around in the reaction flask are 10.6g of PdCU, 60g CuCI and 500mL of aqueous dimethylformamide (made by mixing 62.5mL dH20 and 437,5mL DMF). Dimethylformamide (DMF) is not the same as the watched chemical known as N-methylformamide. 

The dimethylformamide is available as technical grade DMF from the Grasselli Chemicals Department of E. I. duPont de Nemours and Company, Wilmington, Delaware. 

Snatzke has found that a solution prepared from chromium trioxide and dimethylformamide with a small amount of sulfuric acid has similar chemical properties as the Sarett reagent. It is useful with acid sensitive compounds and oxidation occurs at such a moderate rate that selective oxidations are often possible. Although the position allylic to a A -double bond is not attacked, the 3-hydroxy-A -system cannot be oxidized satisfactorily to the cor-... 

The fact that these kinds of chemical reactions occur during the processing were further demonstrated by the testing of the insoluble material in the blends. The data showed that after dimethylformamide (DMF) treatment and after processing, the solubles significantly increased, It also showed that the insoluble content is also related to the TPU content in the blending system. It peaks at the TPU content of 15%-20%, after which the amount drops dramatically. Accordingly, the mechanical properties of the material also showed the same trend. 

Polymer-supported amino alcohols and quaternary ammonium salts catalyze the enan-tioselective addition of dialkylzinc reagents to aldehydes (Table 31). When the quaternary ammonium salt F is used in hexane, it is in the solid state, and it catalyzes the alkylation of benzaldehyde with diethylzinc in good chemical yield and moderate enantioselectivity. On the other hand, when a mixture of dimethylformamide and hexane is used as solvent, the ammonium salt is soluble and no enantioselectivity is observed21. 

Under conditions where the rotation about the C-N bond of dimethylformamide is slow relative to the NMR time scale, the two methyl resonances will be separate singlets. Conversely, if the rotation is made to be very fast, the two methyl groups will be chemically equivalent. Their resonance will then appear as a sharp singlet. In between these extremes, kinetic information can be extracted from the line shapes. In most systems the parameter that is changed to go between these limits is the temperature. In some systems, pH or pressure has the same effect. 

N)-Ethy 1 lactate (98%) and imidazole (99+%) were purchased from Aldrich Chemical Co. TBDMSC1 was purchased from FMC Corporation (submitters) or Aldrich (checkers). A newly opened bottle of dimethylformamide (ACS Reagent grade, 0.02% water) was used as received. 

Lithol Rubine BK (E 180, Cl Pigment Red, Rubin Pigment, Carmine 6B) is a mono azo dye, chemical name calcium 3-hydroxy-4-(4-methyl-2-sulfonatopheny-lazo)-2-naphthalenecarboxylate. It is a red powder, slightly soluble in hot water (90°C), insoluble in cold water, insoluble in ethanol. The absorption maximum is 442 mn in dimethylformamide with Ej. = 200. It is not permitted in the US and is restricted to cheese coloring in the EU. "... 

Anhydrous N.N-dimethylformamide (water <0.005%) is purchased from the Aldrich Chemical Company, Inc., and transferred via cannula directly from the Sure/Seal bottle into the reaction flask. The solvent is deoxygenated by bubbling nitrogen through it for 45 min prior to the addition of compound 2. 

Dimethylformamide (Aldrich Chemical Company, Inc.) was distilled from phosphorus pentoxide and stored over molecular sieves. 

Zinc powder, obtainable from Mallinckrodt Chemical Works, St. Louis, Missouri, and Merck and Co., Rahway, New Jersey, is placed in a beaker and is washed consecutively and rapidly ( 10 seconds) with three 100-ml. portions of 3% hydrochloric acid, two 100-ml. portions of water, two 200-ml. portions of 2% aqueous copper sulfate (until blue color disappears), two 200-ml. portions of water, two 100-ml. portions of acetone, two 100-ml. portions of dimethylformamide, and is washed into the reaction vessel with dimethylformamide. This procedure is a modification of one described by Hennion and Sheehan.3... 

The first microscopical computation of a free energy curve for a chemical reaction in solution was performed by the Jorgensen s group [41,52,53] ten years ago. They studied the degenerate SN2 reaction of chloride anion with methyl chloride in gas phase, in aqueous solution and in dimethylformamide (DMF) ... 

Dimethylformamide (DMF), dioxane, piperidine, methylene chloride, acetonitrile, trimethyl orthoformate (TMOF), sodium borohydride, diisopropylcarbodiimide, and trifluoroacetic acid (TFA) were purchased from Aldrich Chemical Company, Inc. and used without further purification. All of the diversity reagents were purchased from Aldrich except for Fmoc-glycine-OH, which was purchased from Novabiochem. 

FIGURE 2.47. Polarograms obtained for the electrochemical reduction of the diphenyl-methyl radical produced by the reaction of diphenylmethyl chloride by photo-injected electrons in dimethylformamide are shown at two different measurements times (o, 7 ps , 500 pis) in the absence (a) and presence of 8.15 mM methanol (b). Adapted from Figure 1 of reference 50a, with permission from the American Chemical Society. 

Solid state oxidation, both of the a- and the 3-phase [8] of dihydroquinacridone, affords crude a-quinacridone. Subsequent milling with salt in the presence of dimethylformamide produces the 7-modification, while the 3-form evolves in the presence of xylene. Solution oxidation of dihydroquinacridone, possibly performed as air oxidation in the presence of 2-chloroanthraquinone [9], forms crude 3-quinacridone. Milling with xylene likewise affords 3-quinacridone pigment (see tables of chemical structures on p. 613). 

Valentine and Curtis (1975) extended the synthetic utility of potassium peroxide by reporting the successful solubilization of K02 in dry dimethyl sulfoxide using dicyclohexyl- 18-crown-6 ([20] + [21]). Corey et al. (1975) used 18-crown-6 to solubilize KOz in dimethylformamide, dimethoxyethane and diethyl ether, whilst Johnson and Nidy (1975) reported its solubilization in benzene. A wide variety of chemical transformations have been realized with K02 complexes of crown ethers. With alkyl halides the main reaction products are peroxides, alcohols and olefins (Johnson and Nidy, 1975). Peroxides are... 

These include hydrazine, dimethylsulfoxide (DMSO), formamide and some derivatives (N-methylformamide and dimethylformamide), acetamide and some derivatives, and pyridine N-oxide. Some salts such as potassium acetate also intercalate kaolinites. Once intercalated by one of these small molecules or salts, other molecules which normally do not directly intercalate kaolins can be introduced by replacement. Further, the exposure of the inner surfaces by intercalation gives one the opportunity to alter the interlayer bonding of the kaolin layers by chemical modification of the inner surfaces. 

The submitters used ethyl formate, 97%, available from Janssen Chimica, without further purification. Dimethylformamide (DMF) can be used instead of ethyl formate with the same operating conditions. The checkers used ethyl formate (99%), available from Aldrich Chemical Company, Inc., without further purification. 

G.L. Kennedy, H. Sherman, Acute and subchronic toxicity of dimethylformamide and dimethylacetamide following various routes of administration, Drug and Chemical Toxicology, 9 (1986) 147-170. 

What makes FHF an attractive species to investigate by nmr spectroscopy is that it consists of three nuceli each with spin 1/2 bonded directly. Also, the proton of the strong hydrogen bond should have an unusual chemical shift. Early work failed to detect the expected F doublet and H triplets (e.g. Soriano et al., 1969), and it was not until the importance of the solvent was appreciated that coupling was observed (Fujiwara and Martin, 1971, 1974a,b). Suitable media were found to be the dipolar aprotic solvents acetonitrile, nitromethane and dimethylformamide. 

Synonyms AI3-03311 BRN 0605365 Caswell No. 366A CCRIS 1638 Dimethylformamide Dimethylmethanamide 7V,N-Dimethylmethanamide DMF DMFA Dynasolve 100 EINECS 200-679-5 EPA pesticide chemical code 366200 W-Formyldimethylamine NC1-C60913 NSC 5536 U 4224 UN 2265. 

N,N-Dimethylformamide is distilled from calcium hydride at 71° (32 mm.) and stored under argon. The checkers used a freshly opened bottle of the product (white label grade) available from Eastman Organic Chemicals. 

N,N-Dimethylformamide, obtained from Allied Chemical Corporation, was purified by distillation under reduced pressure, b.p. 39-41° (6 mm.). 

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