Charge-coupled devices detection

Fig. 8 PossibUities for on-line coupling of thin-layer chromatography with physical measurement and determination methods. CCD = Charge Coupled Device Detection.

V. Hlady, J. N. Lin, and J. D. Andrade, Spatially resolved detection of antibody-antigen reaction on solid/liquid interlace using total internal reflection excited antigen fluorescence and charge-coupled device detection, Biosens. Bioelectron. 5,291-301 (1990). 

D. A. Sadler and D. Littlejohn, Use of multiple emission lines and principal component regression for quantitative analysis in inductively coupled plasma atomic emission spectrometry with charge coupled device detection, J. Anal. At. Spectrom., 11, 1996, 1105-1112. 

Qin, J., Fung, Y, Zhu, D. and Lin, B. (2004) Native fluorescence detection of flavin derivatives by microchip capillary electrophoresis with laser-induced fluorescence intensified charge-coupled device detection. J Chrom A, 1027 (1-2), 223-229. 

Jose, A.M.P., Luisa, F.G.B., and Nieves, M.S.G., 2011. Flow injection chemiluminescence determination of vitamin B using on-line UV-persulfatephotooxidation and charge coupled device detection. Luminescence. 26 536-542. 

Cosgrove, J. A., and Bilhom, R. B. (1989). Spectrometric analysis of planar separations using charged-coupled device detection. J. Planar Chromatogr.—Mod. TLC 2 362-367. 

Garcia Sanchez, F., Navas Diaz, A., and Fernandez Correa, M. R. (1993). Image analysis of photochemically derivatized and charge-couple-device-detected phenothiazines separated by thin layer chromatography. J. Chromatogr. 655 31-38. 

ConnaUy R., J. Piper. Sohd-state time-gated luminescence microscope with ultraviolet light-emitting diode excitation and electron-multiplying charge-coupled device detection, J. Biomed. Opt., 13, 034022-1 to 034022-6 (2008). 

The analytical capabilities of LIBS and LA-MIP-OES were recently noticeably improved by use of an advanced detection scheme based on an Echelle spectrometer combined with a high-sensitivity ICCD (intensified charge-coupled device) detector. 

Jackson, P., The use of polyacrylamide-gel electrophoresis for the high-reso-lution separation of reducing saccharides labeled with the fluorophore 8-ami-nonaphthalene-l,3,6-trisulfonic acid. Detection of picomolar quantities by an imaging system based on a cooled charge-coupled device, Biochem. ]., 270, 705, 1990. 

In recent years no truly new basic principles have been introduced for the detection of luminescence. However, the technical evolution in the field of microelectronics and optoelectronics, charge coupled device (CCD) detectors, fiberoptics, assembly techniques, and robotics resulted in the introduction on the market of new generations of instruments with increased performance, speed, and ease of handling. In this chapter, some of their typical features will be reviewed. To keep this presentation at a concrete level and to illustrate some specific item, instruments of different makes will be referred to. However, this does not imply they are better than those not cited. It is more a matter of availability of recent documentation at the time of writing. Note that numerical values cited typically relate what can be done today and may vary from one instrument to another from the same company. 

Phaseolicola by charge coupled-device-enhanced microscopy Nitric-oxide-releasing compounds detection by bioluminescent Escherichia 206... 

Using the same PAbs an optical biosensor system has been developed for 2,4,6-TCP [224]. The principle is the detection of laser-induced fluorescence (LIF) in single microdroplets by a homogeneous quenching fluorescence immunoassay (QFIA). The competitive immunoassay occurs in microdroplets (d=58.4 mm) produced by a piezoelectric generator system. A continuous Ar ion laser (488 nm) excites the fluorescent tracer and its fluorescence is detected by a spectrometer attached to a cooled, charge-coupled device (CCD) camera... 

---