Intensified charge couple device

The analytical capabilities of LIBS and LA-MIP-OES were recently noticeably improved by use of an advanced detection scheme based on an Echelle spectrometer combined with a high-sensitivity ICCD (intensified charge-coupled device) detector. 

Alarie J.P., Stokes D.L., Sutherland W.S., Edwards A.C., Vo-Dinh T., Intensified charge coupled device-based fiberoptic monitor for rapid remote surface-enhanced Raman-scattering sensing, Appl. Spectrosc. 1992 46 1608-1612. 

The Experimental Technique chapter describes our experimental setup with the following main parts laser source (Ar, excimer, Nd-YAG, nitrogen, dye, OPO), imaging monochromator, gated detector (Intensified Charge Coupled Device) and computer with corresponding software. The main features of the experimental devices are described, which enable us to accomphsh time-resolved detection. 

The detonation wave diffraction at the initiator/main detonation tube was observed using high-speed Schlieren and CH -chemiluminescence imaging which utilized a 10-nanometer FWHM interference filter centered at 430 nm and both DRS Hadland and Princeton Instruments intensified charge-coupled device (CCD) cameras. 

Qin, J., Fung, Y, Zhu, D. and Lin, B. (2004) Native fluorescence detection of flavin derivatives by microchip capillary electrophoresis with laser-induced fluorescence intensified charge-coupled device detection. J Chrom A, 1027 (1-2), 223-229. 

A.B. Thompson, E.M. Sevick-Muracka, Near-infrared fluorescence contrast-enhanced imaging with intensified charge-coupled device homodyne detection measurement precision and accuracy, J. Biomed. Opt. 8, 111-120 (2003)... 

Since 1997, we have been using in our laboratory an intensified charge-coupled device (ICCD, Oriel model Instaspec V, with a minimum temporal gate of 2.2 ns) in a daily basis for time resolved luminescence studies. The detector has 512x128 pixels in a maximum spectral range of 200 to 900 nm. With a single laser pulse, a fluorescence or a phosphorescence spectrum can be instantaneously obtained, since the combined use of the delay unit and time gate enables one to separate prompt from delayed emissions. 

FRET fluorescence resonance energy transfer FCS fluorescence correlation spectroscopy TIRF total internal reflection fiuorescence PCFI photon counting histogram ICCD intensified charge coupled device EMCCD eiectron muitipiying charge coupled device CMOS complimentary metal oxide semiconductor AFM atomic force microscope. 

Time-resolved absorption spectra of samples of BZP/C12- 1700/EtOH and Cl 2-I5OO/H2O samples were obtained by the use of diffuse reflectance laser flash photolysis technique, developed by Wilkinson et al. [2-4]. In this study, the use of an intensified charge-coupled device as a detector allowed us to obtain time-resolved absorption spectra with nanometer spectral spacing (i.e., where the 200-900 scale is defined by the 512 pixels used for recording spectra in the array of the ICCD) [1,8-14]. 

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