Collagen, bovine

Components/ mechanism of action Human plasma, fibrinogen and thrombin, virally inactivated, hemostat, sealant. Autologous fibrinogen -t-platelet-rich plasma, hemostatic gel. Bovine collagen, bovine thrombin, plus autologous human plasma, hemostatic agent. Bovine collagen and bovine thrombin. Expands 20% which aids in hemostatic effect. [Pg.1106]

Varnavides CK, Forster RA, Cunliffe WJ (1987) The role of bovine collagen in the treatment of acne scars. Br J Dermatol 116 199-206... [Pg.100]

Other treatments may include fluorouracil/epinephrine/bovine collagen gel, an intralesional injection that has been proven effective in clinical trials for refractory patients, or an intralesional injection of interferon. [Pg.1169]

A small number of biotechnology products are classified as medical devices and, hence, are regulated by the Center for Devices and Radiological Health (CDRH). The first approved biotech product to come under the auspices of the CDRH was OP-1 implant. Marketed by Stryker Biotech, OP-1 implant is a sterile powder composed of recombinant human oestrogenic protein-1 (OP-1) along with bovine collagen. It is used to treat fractured bones that fail to heal. The product is mixed with sterile saline immediately before application, and entails surgical insertion of the paste into the fracture. [Pg.95]

Volpin D and Veis A (1973) Cyanogen bromide peptides from insoluble skin and dentin bovine collagens. Biochemistry 12, 1452-1464. [Pg.31]

At day 21 after the first injection, mice are injected intraperi-toneally (i.p.) with bovine type II collagen diluted in saline. A 1 2 dilution of bovine collagen in saline results in a final concentration of 1 mg/ml. Each mouse is injected i.p. with 100 pi of this solution, resulting in a boost injection of 100 pg bovine type II collagen per mouse. [Pg.187]

Living, bi-layered skin substitute containing type 1 bovine collagen Extracted and purified from bovine tendons and viable allogeneic human fibroblast and keratinocytes cells isolated from human infant foreskin... [Pg.934]

In particular, acetylation experiments seemed to lend strong support. Gustavson (1954) found that complete iV-acetylation of bovine collagen does not affect the thermal shrinkage temperature of the fibers. On the other hand, combined iV- and 0-acetylation (blocking both amino and hydroxy groups) lowered T, by approximately 20°C. [Pg.77]

Similar conclusions were made by Gustavson (1962) after a detailed (comparison of bovine collagen with cod collagen, which is largely soluble in weak acid solutions. [Pg.116]

Collagen is a natural fibrous protein found in human cartilage, connective tissue, and bone. Glutaraldehyde cross-linked bovine collagen is a sterile, biocompatible, biodegradable, purified bovine dermocollagen cross-linked with glutaraldehyde, mixed in a phosphate-buffered saline solution. [Pg.885]

Purified solubilized bovine collagen is used as biomaterial for the treatment of soft tissue defects and has been used for the treatment of stress urinary incontinence since the late 1980s (1). Injected material precipitates at body temperature, forming a matrix allowing fibroblastic infiltration and formation of new tissue. It has been used for cosmetic purposes by injection in the dermis to correct scars and other contour deformities of the skin. [Pg.885]

Delayed hypersensitivity reactions after bovine collagen injection for stress urinary incontinence have been reported. [Pg.886]

Mullins RJ, Richards C, Walker T. Allergic reactions to oral, surgical and topical bovine collagen. Anaphylactic risk for surgeons. Aust NZ J Ophthalmol 1996 24(3) 257-60. [Pg.886]

Bonnet C, Charriere G, Vaquier J, Berlin P, Vergne P, Treves R. Bovine collagen induced systemic symptoms ... [Pg.886]

Hyaluronic acid is used topically to promote wound healing. A film containing hyaluronate sodium and carmel-lose is used to prevent surgical adhesion. Hyaluronic acid is increasingly being used in cosmetic dermatology to treat wrinkles in patients who are sensitive to bovine collagen. [Pg.1699]

Fig. 18a-c CRAMPS NMR spectra of bone (200 MHz spectrometer) a bovine collagen ... [Pg.259]

Marrow-Tech, Inc. (Elmsford, NY) has also developed a human skin model. Marrow-Tech s skin equivalent consists of (1) a dermal layer of fibroblasts and naturally secreted collagen and (2) an epidermal layer of keratinocytes separated by a dermal-epidermal junction. Whereas Testskin uses bovine collagen, Marrow-Tech s skin model consists solely of human tissue. [Pg.2652]

The small amounts of 3-hydroxyproline recently identified in bovine collagen do not influence the determination or significance of 4-hydroxyproline measurements (02). [Pg.214]

Rhee, W., et al. Bovine collagen modified by PEG, in J. M. Harris, Poly (ethylene glycol) Chemistry Biotechnical and Biomedical Applications, New York Plenum Press, 1992... [Pg.231]

Amino Acid Bovine collagen Bovine elastin Ichthyocol Herring scales Cornein Spongin ... [Pg.94]

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