Bone mineral content

Since dietary cereals are low in sulfur-containing amino acids, they produce an alkaline urine which favors the retention of bone minerals. In post-menopausal women, there appears to be some interaction between the diet and the effect produced by estrogens on bone mineral content (28). 

ANDERSON J J, CHEN X, BOASS A, SYMONS M, KOHLMEIER M, RENNER J B, GARNER S C (2002) Soy isoflavones no effects on bone mineral content and bone mineral density in healthy, menstruating young adult women after one year. J Am Coll Nutr 21, 388-393. 

Postmenopausal women (mean 66 y) N=912 Observational Bone mineral content of radius, ulna, Os calcis 24-hour diet recall and food frequency data Inverse relationship between bone mineral content of distal radius and ulna and high caffeine intake. 

No overall association between bone mineral content or coffee intake. 

In association with caffeine intake a lower bone mineral content was shown bivariately, but not multivariately, however, there was no relationship between coffee and fracture risk Caffeine intake unrelated to hip or wrist fracture. 

Finally, Yano et al.18 reported a significant negative association between forearm bone mineral content and current caffeine intake among a group of elderly Japanese-American women living in Flawaii, after controlling for intake of milk, calcium, and vitamin D. 

Yano, K., Heilbrun, L. K., Wasnich, R. D., Hankin, J. H., Vogel, J. M., The relationship between diet and bone mineral content of multiple skeletal sites in elderly Japanese-American men and women living in Hawaii, American Journal of Clinical Nutrition, 42, 877, 1985. 

Picard, D., Ste-Marie, L. G., Coutu, D., Carrier, L., Chartrand, R., Lepage, R., Fugere, P., Damour, P., Premenopausal bone mineral content relates to height, weight, and calcium intake during early adulthood, Bone and Mineral Research, 4, 299, 1988. 

However, results obtained by Koo et al. (1991) indicate that low to moderate lead exposure (average lifetime PbB level range of 4.9-23.6 pg/dL, geometric mean of 9.8 pg/dL, n=105) in young children with adequate nutritional status, particularly with respect to calcium, phosphorus, and vitamin D, has no effect on vitamin D metabolism, calcium and phosphorus homeostasis, or bone mineral content. The authors attribute the difference in results from those other studies to the fact that the children in their study had lower PbB levels (only 5 children had PbB levels >60 pg/dL and all 105 children had average lifetime PbB levels <45 pg/dL at the time of assessment) and had adequate dietary intakes of calcium, phosphorus, and vitamin D. They concluded that the effects of lead on vitamin D metabolism observed in previous studies may, therefore, only be apparent in children with chronic nutritional deficiency and chronically elevated PbB levels. Similar conclusions were reached by IPCS (1995) after review of the epidemiological data. 

Fentiman ES, Caleffi M, Rodin A, et al. (1989) Bone mineral content of women receiving Tamoxifen for mastalgia. Br J Cancer 60 262-264... 

Gotfredsen A, Christiansen C, Palshof T (1984) The effect of Tamoxifen on bone mineral content in premenopausal women with breast cancer. Cancer 53 853-857... 

Akesson, K., Grynpas, M.D., Hancock, R. G. V., Odselius, R., and Obrant, K. J. (1994). Energy-dispersive X-ray-microanalysis of the bone mineral content in human trabecular bone - a comparison with ICP-ES and neutron-activation analysis. Calcified Tissue International 55 236-239. 

In the same study by Lloyd et al. (1996), but after 2 years of CCM supplementation, the Ca group versus the placebo group demonstrated significantly higher BMD (12.2% vs 10.1% p =. 005) and bone mineral content increases (BMC 39.9% vs 35.7% p =. 01) for total body, while bone area remained similar between groups (p =. 15). At the lumbar spine and pelvis, supplemental Ca improved bone accretion compared to placebo by as much as 12-24%. Annualized bone acquisition rate was highest in Ca supplemented subjects with above-median values for... 

Prentice, A., Jaqou, L. M., Cole, T. J., Stirling, D. M., Dibba, B., and Fairweather-Tait, S. (1995). Calcium requirements of lactating Gambian mothers Effects of a calcium supplement on breast-milk calcium concentration, maternal bone mineral content, and urinary calcium excretion. Am. J. Clin. Nutr. 62, 58-67. 

Evaluate total bone mineral content of axial and appendicular skeletal features. 

Bone mineral effect. Coffee, taken by 258 healthy occupationally active men aged 40-63 years, significantly reduced the trabecular bone mineral content. The extent of alcohol intake did not differentiate bone mineral content values at the distal radius, whereas the significant detrimental effects of both smoking and coffee drinking on trabecular (but not cortical and total) bone mineral content were revealed. Simultaneously, smokers and ex-smokers, when... 

Consumption by postmenopausal women (6-month parallel-group design) of soy protein (40g/day providing either 56 mg isoflavones/day or 90 mg isoflavones/day) compared to cesin and nonfat dry milk (40g/day) produced significant increases in bone mineral content and density in the lumbar spine (but not in any other parts of the body), but only in the higher isoflavone (90 mg/day) group compared to the control group.Daily intake for 2 years of... 

The long-term use of oxandrolone has been studied in children with very severe bums (covering 40% or more of the body surface). Under controlled conditions, 84 children (56 girls and 28 boys mean age 8 years) received treatment for 1 year with placebo or oral oxandrolone 0.1 mg/kg bd (92). At discharge (95% healed) and at 6, 9, and 12 months after the burn, oxandrolone improved lean body mass, bone mineral content, and bone mineral density compared with placebo and there was no adverse effect on hepatic transaminases. The latter finding, and the absence of other adverse effects, suggests that this treatment of very severely burnt children is defensible. 

Krolner B, Jorgensen JV, Nielsen SP. Spinal bone mineral content in myxoedema and thyrotoxicosis. Effects of thyroid hormone(s) and antithyroid treatment. Clin Endocrinol (Oxf) 1983 18(5) 439 16. 

Toh SH, Brown PH. Bone mineral content in hypothyroid male patients with hormone replacement a 3-year study. J Bone Miner Res 1990 5(5) 463-7. 

Landin-Wilhelmsen K, Nilsson A, Bosaeus I, Bengtsson BA. Growth hormone increases bone mineral content in postmenopausal osteoporosis a randomised placebo-con-trolled trial. J Bone Mineral Res 2003 18 393 105. 

Other Agents That Promote Bone Mineral Content... 

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