Bladder, overactive incontinence

Bladder overactivity is known as urge UI (UUI) and is associated with increased urinary frequency and urgency, with or without urge incontinence. The detrusor muscle is overactive and contracts inappropriately during the filling phase. 

Mixed incontinence includes the combination of bladder overactivity and urethral underactivity. 

The adverse effects of tolterodine and other antimuscarinic anticholinergic drugs have been reviewed in patients with incontinence and bladder overactivity (3-6). 

Anticholinergic/antispasmodic agents are the therapies of choice for bladder overactivity (urge incontinence). 

Various types of UI may coexist in the same patient. The combination of bladder overactivity and urethral underactivity is termed mixed incontinence. This is often a difficult diagnosis to make because of the often-confusing array of presenting symptoms. Bladder overactivity may also coexist with impaired bladder contractility. This is most common in the elderly and is termed detrusor hyperactivity with impaired contractility. ... 

CLINICAL PRESENTATION OF URINARY INCONTINENCE RELATED TO BLADDER OVERACTIVITY... 

UI may present in the setting of concurrent, seemingly unrelated illnesses. New-onset UI may be the initial manifestation of certain systemic illnesses such as diabetes meUitus, metastatic malignancies, multiple sclerosis, and other neurologic illnesses. Central nervous system disease, or injury above the level of the pons, generally results in symptoms of bladder overactivity and UUI. Spinal cord injury or disease may manifest as bladder overactivity and UUI or as overflow incontinence, depending on the spinal level and completeness of the injury or disease. 

The Urological Sciences Research Foundation is a nonprofit organization based in California. It solicits money to fund clinical trials, focusing on prostate disease, erectile dysfunction, overactive bladder, and incontinence. Many of its industry sponsors are well-known pharmaceutical and medical device companies. 

Overflow Urinary Incontinence (OUI) (Urethral Overactivity and/or Bladder Underactivity)4... 

Clinical Presentation of Urinary Incontinence Related to Urethral Overactivity and/or Bladder Underactivity4 ... 

Urethral overactivity and/or bladder underactivity is known as overflow incontinence. The bladder is filled to capacity but is unable to empty, causing urine to leak from a distended bladder past a normal outlet and sphincter. Common causes of urethral overactivity include benign prostatic hyperplasia (see Chap. 82) prostate cancer (see Chap. 65) and, in women, cystocele formation or surgical overcorrection after UI surgery. 

Bladder instability/Overactive bladder For the relief of symptoms of bladder instability/treatment of overactive bladder associated with voiding in patients with uninhibited and reflex neurogenic bladder (eg, urgency, freguency, urinary leakage, urge incontinence, dysuria). 

Overactive bladder Treatment of patients with an overactive bladder with symptoms of urinary frequency, urgency, or urge incontinence. 

Overactive bladder For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary freguency. 

Solifenacin Succinate Tablet For overactive bladder with urge urinary incontinence urgency urinary frequency... 

Indications Overactive bladder syndrome, Urinary incontinence Category Muscarinic antagonist Half-life 7 hours... 

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