Black cumin seeds

In ancient times, the alkaloids were used also for other purposes. It is known that black cumin seeds contain dopamine, which has been used historically in the Middle East and India as traditional tonic for many aliments, in confectionery, and in bakeryNowadays, research confirms that these seeds also have a lot of biological compounds also in the seed coat, including sesquiterpene and indazole alkaloids. 

Black cumin seed oil Nigella sativa L., Ranunculaceae) was tested for its penetration enhancer activity on carvedilol using excised albino Wistar rat abdominal skin. At a concentration of 5% the EO showed the most potent enhancing effects. The transdermal ux and the permeability coef -dent were higher than in the control group (Saima et al., 2010). 

A further study was carried out on the anti-inflammatory effect of the EO of Iranian black cumin seeds (BCS) (N. sativa L. Ranunculaceae) by Hajhashemi et al. (2004). p-Cymene (37.3%) and thymoquinone (13.7%) were found to be the main compounds. For the detection of the anti-inflammatory activity, carrageenan-induced paw edema test in rats was used and also the croton oil-induced ear edema in mice. After oral administration of this EO at various doses no significant anti-inflammatory effect could be observed in the carrageenan test, whereas i.p. injection of the same doses significantly reduced carrageenan-induced paw edema. At doses of 10 and 20 pL/ear, BCS-EO also caused a reduction of a CTOton oil-induced edema. An anti-inflanunatory effect could be observed after both systanic and local administration and thymoquinone seemed to play an important role in this pharmacological effect. 

Hajhashemi, V., A. Ghannadi, and H. Jafarabadi, 2004. Black cumin seed essential oil, as a potent analgesic and antiinflammatory drug. Phytother. Res., 18(3) 195-199. 

Linoleic acid (18 2n-6) is an essential fatty acid that must be obtained through diets. In this section, fruit, spice, and herb seed oils rich in linoleic acids are summarized. These seed oils include watermelon, melon Cucumis melo and Colocynthis citrullus), goldenberry, grape, rose fruit, paprika, red pepper, onion, black cumin, and Onagraceae seed oils. Several seed oils may be listed in other sections if they contain significant level of a special fatty acid. For example, pumpkin seed oils rich in both oleic acid and linoleic acid, are listed under the section named, Edible seed oils rich in oleic acid (18 ln-9). ... 

Red pepper, Onion, Black cumin, and Onagraceae stand for red pepper, onion, black cumin, and Onagraceae seed oil. Numbers correspond to the references cited, nd stands for not detected. 

In contrast to the thousands of alkaloids containing an indole, or 2,3-dihydroindole, nucleus, there is only a handful that contain an indazole moiety the sulfate 30, for example, was isolated from black cumin, Nigella sativa (2008JNP1111), the seeds of which are used as a spice. 

Panch Puran Fenugreek seed, nigella, cumin seed, black mustard seed, fennel seed... 

Salim El, Fukushima S (2003) Chemopreventive potential of volatile oil from black cumin (Nigella saliva L.) seeds against rat colon carcinogenesis. Nutr Cancer 45 195 Schera JM, Burgessb EJ, Lorimerb SD, Perry NB (2002) A cytotoxic sesquiterpene and unprecedented sesquiterpene-bisbibenzyl compounds from the liverwort Schistochila glaucescens. Tetrahedron 58 7875... 

Spices Allspice (Jamaica, Whole), Anise Seed, Basil (Sweet), Bay Leaves. Caraway Seed, Celery Seed, Cinnamon (Stick), Coriander (Whole), Cumin Seed, Dill Seed, Fennel Seed (Whole), Marjoram, Mustard (Mayonnaise), Oregano, Parsley (Shredded), Black Pepper (Whole), Cayenne Pepper R No ... 

Mole Negro GuajiUo chiUi, mulato pasiUa chilli, chdle chipotle mora, sesame seed, peanut, almond, walnut, pecan, raisin, semi-sweet role, cinnamon, black pepper, clove, cumin, thyme, Mexican oregano, bay leaf... 

Dukkha Hazelnut, cumin, sesame, coriander seed, black pepper... 

Spices had TPC ranging from 11,319 to 24,390 for cloves, 7,500-11,900 for Ceylon cinnamon, 230-9,000 for cumin, 610-6,750 for caraway, 3,600 for capers, 148-2,420 for cardamom, 1,610-2,200 for nutmeg, 2,117 for dried turmeric, 1,600-2,020 for star anise, 300-1,700 for black pepper spice, 134—1,250 for coriander seed, 830 for fenugreek seed, 780 for white pepper spice, 317-630 for dried ginger, 380 for green pepper spice, 201-221 for fresh ginger, and 90 for dried horseradish. Curry powder had TPC of 1,075 among spice blends. 

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