Biochemical significance of the

However, the biochemical significance of the latter studies is challenged by the fact that the transformation of transient purine and pyrimidine radicals into diamagnetic decomposition products is oxygen-independent in the solid state. Therefore, it is necessary to study the chemistry of one-electron nucleobase intermediates in aerated aqueous solutions in order to investigate the role of oxygen in the course of reactions that give rise to oxidation products within DNA and model compounds. In this respect, type I photo-... 

Biochemical Significance of the Phenylalanine-Cinnamate Pathway in Plants and Fungii... 

Lorimer, G. H., The carboxylation and oxygenation of ribulose-1,5-bisphosphate The primary events in photosynthesis and photorespiration. Ann. Rev. Plant Physiol. 32 349, 1981. Mechanisms and biochemical significance of the carboxylase and oxygenase reactions. 

Lenaz, G., Sechi, A. M., Masotti, L., and Parenti-Castelli, G. Lipid-protein interactions in mitochondria. II. On the nature and biochemical significance of the interaction between phospholipids and lipid-depleted mitochondria. Arch. Biochem. Biophys. 141, 89-97 (1970). 

It has been proposed that a low molecular weight phosphoprotein of phosvitin nature (47) which binds iron with high affinity may be involved in the cytosolic transport of iron in liver cells (48, 49), but no energized uptake of iron has been demonstrated such as in isolated rat liver mitochondria using a Fe(III)-phosvitin from avian egg yolk (mol wt 40,000) as the substrate (50). The biochemical significance of the cytosolic iron binding phosphoprotein is therefore still uncertain. 

Biochemical Significance of the Iron Transporting System of Mitochondria... 

Willumsen, B.M., Norris, K., Papageorge, A.G., Hubbert, N.L., and Lowy, D.R. (1984). Harvey murine sarcoma virus p21 ras protein biological and biochemical significance of the cysteine nearest the carboxy terminus. EMBO J 3 2581-2585. 

Attempts at identification of the activity of this protein have not been successful thus far. It does not have any activity akin to that of carbonic anhydrase, alcohol dehydrogenase, carboxypeptidase, or dehydropeptidase. In this sense, it can be compared to hepatocuprein, hemocuprein, or the copper protein of Mohamed and Greenberg (1954) (possibly identical with hepatocuprein), all metalloproteins without identified enzymatic activity. Further studies along these lines may reveal the biochemical significance of the presence of this protein. 

The biochemical significance of the nucleotides and nucleosides is unquestioned. In view of the Increasing use of diagnostic ultrasonics in medicine some interest has developed in the study of the acoustic properties of such molecules. The pH dependence of the acoustic absorption has been studied by Zana and coworkers (1). Our interest has been confined to the study of sound absorption in approximately neutral solutions of these molecules. Sound velocity studies have been of interest also (2)(3)(4) but will not be discussed here. 

The biochemical significance of the vitamin resides in its being a necessary precursor in the biosynthesis of CoA. Depending on the capabilities of the organism, pantoic acid (or /3-alanine), or pantothenic acid, or pantetheine must be supplied. 

Katayama, T. Volatile constituents of algae. XX. Pharmacological action of volatile constituents and biochemical significance of the existence of acrylic acid. Chem. Abstr. 62, 10822h (1965). 

The fireflies, railroad worms, and click beetles use the same luciferin in their luminescence reactions. Recent studies on the railroad worms and the click beetles have greatly contributed to the biochemical understanding of the firefly bioluminescence (see Section 1.2). Concerning luminous Diptera, significant progress has been made only recently. 

Table 1 shows some biochemical properties of the pectolytic enzymes present in pool 1. The pectin lyase/pectate lyase activities (pool I) and polygalacturonase activity (pool II) were not significantly affected by NH4+, Na+ and K+ (0,25 - 2,5mM), while Al +, p-mercaptoethanol, Hg2+, EDTA, Ba + and Zn+2 (2,5mM) inhibited 30-100% these activities. On the other hand, Ca2+, Mg + and Mn + at 2,5mM concentration activated 20-100% pectin/pectate lyases but Ca " " and Cu " " (2,5mM) inhibited polygalacturonase activity about 42 - 70%. 

Pullman, A., and B. Pullman. 1980. Electrostatic Effect of Macromolecular Structure on the Biochemical Reactivity of the Nucleic Acids. Significance for Chemical Carcinogenesis. Int. I. Quant. Chem., Quant. Biol. Symp. 7, 245. 

The synthesis of arginine from citrulline. The latter is produced from other amino acids in the small intestine and then released into the blood. The kidney takes up citrulline and converts it to arginine, which is then released into the blood for use by other tissues (Figure 8.18). Since arginine is a precursor for a number of important compounds, and aids wound healing, this is a significant biochemical role of the kidney. 

This covalent bonding arises as a result of biochemical oxidation of the thiol groups in two cysteine residues, and it may also be achieved chemically with the use of mild oxidizing agents. This modification of thiol groups may thus loop a polypeptide chain or cross-link two separate chains. It also significantly modifies the properties of a... 

TNO considered that the biological significance of the critical adverse effect in terms of its presumable health consequence should be considered in the selection of assessment factor (Hakkert et al. 1996). For example, a reversible change in a biochemical parameter of doubtful toxicological significance may warrant the use of an additional factor smaller than 1, whereas, e.g., microscopically visible tissue damage may indicate application of a factor higher than 1. The default value is 1. 

The true biochemical significance of this deamination, and the function of the secondary metabolic pathway originating from L-phenylalanine (6-... 

Bernheim, F. (1943). The significance of the amino groups for the oxidation of various compounds by the Cholera vibrio (V. comma). Arch. Biochem. 2, 125-133. 

---