Beilstein Information System

Beilstein Beilstein Information Systems, Inc. organic chemistry. nu- meric, struc- ture >8mio subst., >5 mio reactions 180 journals Beilstein Handbook MDL Information Systems GmbH commercial online, Chemweb, Crossfire quarterly wuAo.beilstein.- com... 

Bei/stein On-line, Beilstein Information Systems GmbH, Springer Vedag, Heidelberg, Germany. 

Chemical Abstracts online and its search module, SciFinder, are available from the American Chemical Society, http //www.cas.org/SCIFINDER/ 2004. The Beilstein Information Systems is available from http //www.beilstein.com/. 

Beilstein Handbook, Beilstein Information Systems, Frankfurt, Germany. 

The Beilstein Information Systems is available from, http //www. beilstein.com/, 2006. 

Current Facts in Chemistry Beilstein Information Systems, Inc. 

A new and valuable literature based database and search system, called NetFire, has recently been made available on the Internet by Beilstein Information Systems. It is the first attempt by Beilstein to provide chemical information outside the main area of extracted and evaluated data. The existing Beilstein system, provided via their CrossFire system, is an in-house system which has received wide acceptance since it was introduced in the mid 1990s. NetFire is a very new and different system, a valuable Internet resource. It is yet another example of the innovation of new and modem electronic products by Beilstein. NetFire provides free access to titles, abstracts, and authors from the organic chemical literature, from 1980 to the present. ... 

Beilstein Information Systems, NetFire Information, the Beilstein Abstracts Database, http //www.beilstein.com/netfire/netfire.html... 

Figure 8 Reaction record from the CrossFire plus Reactions database (reprinted with permission of Beilstein Information Systems. Inc.)...

Many producers and public hosts offer reduced rates for academics or full academic programs , making expensive retrieval systems and databases affordable for academic institutions (e.g., MDL, retrieval system ISIS plus several databases Beilstein Information Systems, CrossFire FIZ Chemie, reduced rates for both Cheminform RX in house and at the host STN Springer/Infochem Synopsys). However, CASREACT is unfortunately not included at this time in the otherwise very useful CAS academic program. ... 

AutoNom is distributed in Europe by Beilstein Informationssysteme GmbH and in the USA by Beilstein Information Systems, Inc. (see Beilstein informationssysteme GmbH). 

The ROSDAL (Representation of Organic Structures Description Arranged Linearly) syntax was developed by S. Welford, J. Barnard, and M.F. Lynch in 1985 for the Beilstein Institute. This line notation was intended to transmit structural information between the user and the Beilstein DIALOG system (Beilstein-Ohlme) during database retrieval queries and structure displays. This exchange of structure information by the ROSDAL ASCII character string is very fast. 

Specinfo, from Chemical Concepts, is a factual database information system for spectroscopic data with more than 660000 digital spectra of 150000 associated structures [24], The database covers nuclear magnetic resonance spectra ( H-, C-, N-, O-, F-, P-NMR), infrared spectra (IR), and mass spectra (MS). In addition, experimental conditions (instrument, solvent, temperature), coupling constants, relaxation time, and bibliographic data are included. The data is cross-linked to CAS Registry, Beilstein, and NUMERIGUIDE. 

Beilstein Database are described in The Beilstein System Strategies for Effective Searching, ed. S. R. Heller (Washington, DC American Chemical Society, 1997). In the 1990s, the Beilstein Institute together with MDL produced an Internet-based client-server system of the Beilstein Database, CrossFire Beilstein, which is now owned and updated by Elsevier Information Systems, Frankfurt. 

ROSDAL. Linear notation scheme devised by the Beilstein Institute. It can contain just connection table information, or it may also contain atom coordinates. Several chemical information systems can convert ROSDAL strings to other structure file formats. 

Fig. A.l. Structure Search for CrossFire Beilstein Beilstein Data Copyright (c) 1988-2006, Beilstein Institut zur Foerdening der Chemischen Wissenschaften licensed to Beilstein GmhH and MDL Information Systems GmbH. All rights reserved.

Vanco, J. (2003) The Beilstein CrossFire Information System and its use in pharmaceutical chemistry. Ceska Slov. Farm. 52, 68-72. 

Beilstein grid, example of entries, 8l-82,84f Beilstein Handbook entry, 8l main series, 8l supplementary series, 8l Beilstein information pool future concept, 89,90f state of progress, 88-89,90f Beilstein system... 

Four chapters on other operational substructure search systems follow. Jean Marcah and co-workers describe the Du Pont global technical information system Steve Welford and Clemens Jochum report on chemical structure registration for Beilstein Online Peter Rusch also covers Beilstein Onhne in a paper about substructure searching on Dialog and the DARC Toolkit which was described by Pascal Huguet is summarised in a chapter written by Bill Town with some suggestions from myself and Pierre Buffet of Questel. 

For the purpose of unambiguity in the selection of preferred names, the two most important producers and distributors of chemical information, i.e., CAS (see Chemical Abstracts Service Information System) and the Beilstein Institute (Beil-stein), devised nondocumented ad hoc sub-rules which only amplified the difficulty of uniquely naming organic compounds (see Factual Information Databases). These rules were necessary since lUPAC recommendations frequently allow more than one name for a given chemical compound. As a result, both institutions revised the lUPAC system and created their own systematic lUPAC-compatible rather than lUPAC-sanctioned nomenclatures. In addition, trivial or trade names, being shorter and more concise, have successfully replaced systematic names for a number of chemical compounds which are of commercial importance or are the subject of public concern, e.g., pharmaceuticals, insecticides, or pollutants. Both CAS and Beilstein claim to conform to the lUPAC rules and in general it is true. The lUPAC recommendations were consciously formulated to allow considerable freedom in... 

MDL Information Systems GmbH. The Beilstein Database. [Online]... 

Searching journal information continues to be the primary use of SciFinder for the medicinal chemist. One finds it especially useful for searching various topics, for instance, anti-inflammatory treatments. When performing structure/reaction-based searches, many chemists also use Beilstein CrossFire in conjunction with SciFinder. The reaction information from these systems is often complementary, and it is quite useful to have both SciFinder and CrossFire in a medicinal chemistry group. However, companies with restricted budget may have to choose one or the other. 

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