Beilstein-Institut

The ROSDAL (Representation of Organic Structures Description Arranged Linearly) syntax was developed by S. Welford, J. Barnard, and M.F. Lynch in 1985 for the Beilstein Institute. This line notation was intended to transmit structural information between the user and the Beilstein DIALOG system (Beilstein-Ohlme) during database retrieval queries and structure displays. This exchange of structure information by the ROSDAL ASCII character string is very fast. 

Stmcture searching and display software are host-specific. The Softon Substmcture Search System (S4) was developed by the Beilstein Institute and Softon of Graefelfing Germany (50). It is a full stmcture and substmcture searching module. The S4 is used in-house by the Beilstein Institute and is operated by DIALOG. STN uses CAS ONLINE s messenger software for on-line stmcture searching of the Beilstein on-line database (51). 

Design Institute for Physical Properties Research, Project 801, Data Compilation 1995 Beilstein Online Beilstein Institute for Organic Chemistry, Springer-Vedag, Heidelberg, Germany, 1995. 

Dr. Gustav Penzlin Beilstein Institut (ur Literatur der Organischen Chemie VarrentrappstraBe 40—42 D-60486 Frankfurt... 

C. Helma, S. Kramer and L. De Raedt, The molecular feature Miner MOLFEA, in Proceedings of the Beilstein-Institut Workshop, ed. M.G Hicks and C. Kettner, Molecular Informatics Confronting Complexity, Logos Verlag, Berlin, 2003. 

We are most grateful to Evgeny Byvatov, Norbert Dichter, Uli Fechner, Alireza Givehchi, Lutz Franke, Steffen Renner, and Jochen Zuegge for valuable contributions to this chapter and many stimulating discussions. This work was supported by the Beilstein-Institut zur Forderung der Chemischen Wissenschaften. 

Beilstein Database are described in The Beilstein System Strategies for Effective Searching, ed. S. R. Heller (Washington, DC American Chemical Society, 1997). In the 1990s, the Beilstein Institute together with MDL produced an Internet-based client-server system of the Beilstein Database, CrossFire Beilstein, which is now owned and updated by Elsevier Information Systems, Frankfurt. 

Beilstein Journal of Organic Chemistry [BeilsteinJ. Org. Chem] (2005-). Electronic journal. Open access. Free online full-text archive from 2005. Publisher Beilstein-Institut, Frankfurt am Main, Germany. 

Beilstein uses a number of additional stereochemical descriptors for specialised situations. Examples are (RS), R, S, and H. For full details, see the booklet Stereochemical Conventions in the Beilstein Handbook of Organic Chemistry, issued by the Beilstein Institute, and Section 7.6. 

Begley, M. J., Crombie, L Griffiths, G. L. and Tone, R. C. F. (1981). Charge-transfer and non-charge-transfer crystal forms of (E)-(5,5 -dimesitylbifuranylidenediones and X-ray stractural investigation. J. Chem. Soc., Chem. Commun., 823-5. [216] Beilstein Institute (1978). How to use Beilstein. Beilstein handbook of organic chemistry. Beilstein Institute, Frankfurt. 

How to Use Beilstein, Beilstein Institute, Springer-Verlag, Berlin, 1978. 

The Beilstein Database. The Beilstein Database, with over 8 million structures, is the oldest in existence, based on the Beilstein Handbook of Organic Chemistry, and contains data that extend back to 1771. The database is produced by the independent Beilstein Institute... 

ROSDAL. Linear notation scheme devised by the Beilstein Institute. It can contain just connection table information, or it may also contain atom coordinates. Several chemical information systems can convert ROSDAL strings to other structure file formats. 

Fig. A.l. Structure Search for CrossFire Beilstein Beilstein Data Copyright (c) 1988-2006, Beilstein Institut zur Foerdening der Chemischen Wissenschaften licensed to Beilstein GmhH and MDL Information Systems GmbH. All rights reserved.

The Beilstein-Institut also took over the publication of Elsevier s Encyclopaedia of Organic Chemistry. Following the publication of four parts of Supplement V of the fourteenth volume of Elsevier on steroids and triterpenes (in English, but under the auspices of the Beilstein-Institut), further volumes will appear in the Beilstein Handbuch series. 

Beilstein. 1771-. Frankfurt, Germany Beilstein Institute. According to the Institute, this is the world s largest database in the area of organic chemistry. Coverage and includes over 35 million records with 9.3 million chemical structures. Chemical identiflcation for each record includes the chemical... 

We are indebted to Dr. A. J. Lawson (Managing Director of the Beilstein Institut, Frankfurt am Main, FRG) for valuable advice in preparing the manuscript. 

Organizations such as the Chemical Ahstacts Service and the Beilstein Institute that prepare indexes to the chemical literature must adopt a system for selecting unique names in order to avoid excessive cross referencing. Chemical Abstracts Service uses a system which groups together compounds derived from a single parent compound. Thus most index names are inverted (e.g.. Benzene, bromo rather than bromobenzene Acetic acid, sodium salt rather than sodium acetate). 

Beilstein-Institut, Varrentrappstr. 40-42, D-6000 FVankfurt 90, Federal Republic of Germany... 

Beilstein-Institut, 80,88 Chemical Abstracts Service, 128 Fachinformationszentrum Energie Physik Mathematik GmbH, 143 Fein-Marquart Associates, Inc., 62 G. D. Searle Co., 18 Hampden Data Services, 9... 

The authors are grateful for the cooperation of Dr Clemens Jochum and his co-workers at the Beilstein Institut in the testing of HTSS on large databases and gratefully acknowledge the advice of Dr S R Heller for a period of more than a decade. 

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