Awareness training package

The precursor was identified in the maintenance sub-process. In practice, the operators from technical support observed the presence of substances inside the packaging machines. Subsequently, they consulted the chief operator on how to remove the substances from the machines and perform the most suitable intervention. These actions correspond with the control elements on the operational control level. The actions were performed in order to resume production quickly, and adhere to planned schedules. Additionally, experience and training provided the operators with guidelines on how to perform the maintenance effectively. In practice the production manager, responsible for any preventive solutions was not aware of the existence of this precursor and consequently had no overview of these deviations even though the company s quality and safety standards required an overview of all deviations and... 

Normally, the rate of production of lead azide is geared to the rate at which it can be incorporated in explosive trains. In this manner the total quantity on hand is minimized and is broken down into small lots and packaged so that the accidental detonation of one component will be less likely to result in the sympathetic detonation of large stores. However, during the South East Asia conflict a substantial overproduction of lead azide occurred, and bulk quantities were produced far in excess of normal rates. This situation required a special awareness of three problems which, although always of concern, do not normally assume such proportions. These were the problems associated with bulk storage and handling of the finished product with the accumulation of hazardous waste... 

A number of comparative/validation smdies have been conducted using external data or prospective bioassay smdies from the US NTP [e.g., Benigni and Zito (2004), Mayer et al. (2008)]. Essentially, the predictive performance may differ from different batches of chemicals. Each of these software packages has its own unique strengths and weaknesses for which the user should be aware. It is advisable to test drive the software using tested chemicals that are structurally related to your query chemical to ascertain that the software is properly trained. Use of more than one software is also advisable to compare and contrast in light of the rationales given. 

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