Autoregulation

Resistance of LEW rats to mercury-induced autoimmunity is due neither to CD8+ suppressor cells since treatment with an anti-CD8 mAb does 

Aten J (1992) Autoreactivity to renal antigens in models of polyclonal B cell activation. Thesis, University of Leiden, p 22 

Aten J, Bosman CB, Rozing J, Stjnen T, Hoedemaeker PJ, Weening JJ (1988) Mercuric chloride-induced autoimmunity in the Brown Norway rat. Cellular kinetics and major histocompatibility complex antigen expression. Am J Pathol 133 127-138 

Aten J, Veninga A, de Heer E, Rozing J, Nieuwenhuis P, Hodemaeker P, Weening JJ (1991) Susceptibility to the induction of either autoimmunity or immunosuppression by mercuric chloride is related to the MHC haplotype. Eur J Immunol 21 611-616 

Aten J, Veninga A, Bruijn JA, Prins FA, De Heer E, Weening JJ (1992) Antigenic specificities of glomerular-bound autoantibodies in membranous glomerulopathy induced by mercuric chloride. Clin Immunol Immunopathol 63 89-102 

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S. Kalsner and T. C. Westfall, eds., Presynaptic Receptors and the Question of Autoregulation of Meurotransmitter Release, Vol. 604, Annals of the New York Academy of Science, New York, 1990. 

So this research reveals new mechanisms of bacterial autoregulation under extreme conditions, controlled by low weight molecules - alkyiresorcinols. It applied aspects are defined by developing of methods for DNA protection in vitro and elongators of bacterial cells viability at UV exposure. 

The role of bacterial growth autoregulators (alkyl hydroxybenzenes) in the response of Staphylococci to stress. Microbiology, Vol.71, No.l, Qanuary 2002), pp.23-29, ISSN 1350-0872... 

Tseng MY, Czosnyka M, Richards H, Pickard JD, Kirkpatrick PJ. Effects of acute treatment with pravastatin on cerebral vasospasm, autoregulation, and delayed ischemic deficits after aneurysmal subarachnoid hemorrhage a phase II randomized placebo-controlled trial. Stroke 2005 36 1627-1632. 

The different growth modes discussed above have been exemplified also from structural studies. Froment and Lincot [247] used structural characterization methods, such as TEM and HRTEM, to determine the formation mechanisms and habits of chemically deposited CdS, ZnS, and CdSe thin film at the atomic level. These authors formulated reaction schemes for the different deposition mechanisms and considered that these should be distinguished to (a) atom-by-atom process, providing autoregulation in normal systems (b) aggregation of colloids (precipitation) ... 

Favelyukis, S., Till, J. H., Hubbard, S. R., and Miller, W. T., Structure and autoregulation of the insulin-like growth factor 1 receptor kinase, Nat. Struct. Biol., 8, 1058-1063, 2001. 

Explain how the myogenic mechanism causes autoregulation of blood flow... 

Interestingly, RBF remains relatively constant when MAP changes in the range of 85 to 180 mmHg. This ability to maintain a constant blood flow in spite of changes in MAP is referred to as autoregulation. The mechanism of... 

Autoregulation of RBF is an intrarenal response. In other words, the mechanisms responsible for autoregulation function entirely within the kidney and rely on no external inputs. Two mechanisms elicit this response ... 

Chen N., Reith M. Autoregulation and monoamine interactions in the ventral tegmental area in the absence and presence of cocaine a microdialysis study in freely moving rats. J. Pharmacol. Exp. Ther. 271 1597, 1994. 

Cunningham K., Paris J., Goeders N. Chronic cocaine enhances serotonin autoregulation and serotonin uptake binding. Synapse. 11 112, 1992. 

Blood pressure lowering drugs reduce risk of stroke (and myocardial infarction and death) in middle aged patients and even better in the elderly (NNT 86 vs 29 over 5 years) (Pearce 1998). However in the elderly the dysfunction in the autoregulation of brain blood flow, salt and fluids, and increased sensitivity to adverse effects and symptoms may change the picture. 

Mercuric chloride in the BN rat gives a lymphoproliferation in spleen and lymph nodes, including B and T helper cells, an increase in the number of Ig containing cells resulting in a rise in all serum Ig isotypes and an early thymic atrophy [196]. The kinetics of the increase in the serum level of various Ig isotypes were similar to that observed for IgE, suggesting spontaneous autoregulation, which could involve suppressor T cells [ 197, 198] and/or auto-anti-idiotypic antibodies [ 199]. 

In support of the association theory, colloid chemists cited non-reproduceable cryoscopic molecular weight determinations (which were eventually shown to be caused by errors in technique) and claimed that the ordinary laws of chemistry were not applicable to matter in the colloid state. The latter claim was based, not completely without merit, on the ascerta-tion that the colloid particles are large aggregates of molecules, and thus not accessible to chemical reactants. After all many natural colloids were shown to form double electrical layers and adsorb ions, thus they were "autoregulative" by action of their "surface field" (29). Furthermore, colloidal solutions were known to have abnormally high solution viscosities and abnormally low osmotic pressures. 

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