Automated screening

The enormous increase in the number of groups working in this domain, in concert with the advances in the fundamental techniques of chromatography and laboratory automation (screening technologies) have led to the rapid and unprecedented accumulation of data [1]. 

Automated Screening of Cationic Lipid Formulations for Transfection... 

Sumi S, Kidouchi K, Ohba S et al. Automated screening system for purine and pyrimidine metabolism disorders using high performance liquid chromatography. J Chromatogr B Biomed Sci Appl 1995 672 233-239. 

The development and innovation of the agricultural and food industry rely generically on two fundamental axes food safety and food quality. The more and more complexity of the food chain demands the development of efficient traceability systems which guarantee the firmness of all chain links. In this context, a clear priority is defined in the development of molecular methods of detection, analysis and diagnosis. These methods should be rapid, of high sensitivity and should permit automated screening. 

In this chapter some of the recent developments in crystallization-induced resolution are presented. After an introduction to the state-of-the-art of resolution by diastereoisomeric salt formation and some recent developments in identifying new resolving agents, the new and coming generation of automated screening and speed in development will be discussed. 

In general, however, the pure enantiomers of the racemate under study are not available to prepare the diastereoisomerically pure salts. Therefore, the automated screening described earlier has limited application. 

The Chemspeed ASW2000 equipment consists of vortex stirred units of 16 vessels of 10 ml, designed for automated screening and high throughput experimentation. 

Particle Concentration Fluorescence Immunoassay. The PCFIA is a solid-phase immunoassay in which proteins are attached to polystyrene particles by adsorption or covalent coupling for the solid phase and fluorescent-labeled reagents are utilized for product detection.22 The general principles of the assay are similar to those of the enzyme-linked immunosorbent assay (ELISA), which has been reviewed extensively elsewhere.23 PCFIAs are performed in specially designed 96-well format Fluoricon assay plates utilizing an automated Screen Machine (Idexx Corporation, Research Product Division, Portland, ME). 

Batch Executed Semi-Automated Screen Format.190... 

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