Autoimmune/inflammatory syndrome

Inflammatory and immune diseases Autoimmune disease (A,I), asthma (A), osteoarthritis (I), rheumatoid arthritis (I), septic shock (A,I), infections (A,I), familial cold auto-inflammatory syndrome (I), Muckle Wells syndrome (I), chronic infantile neurological cutaneous and articular syndrome/neonatal onset multisystemic inflammatory disease (CINCA/NOMID) (I), Crohn s disease (I), gout (I), acute renal failure (A,l)... 

Zafrir Y, Agmon-Levin N, Paz Z, Shilton T, Shoenfeld Y. Autoimmunity following hepatitis B vaccine as part of the spectrum of Autoimmune (Auto-inflammatory) syndrome induced by Adjuvants (ASIA) analysis of 93 cases. Lupus 2012 21(2) 146-52. 

The eosinophilia myalgia syndrome (EMS) is a complex systemic syndrome with inflammatory and autoimmune components that affects the skin, fascia. 

The autoimmune rheumatic diseases consists of Rheumatoid Arthritis (RA), Spondylarthritis (SpA), Systemic Lupus Erythematosus (SLE), Polymyositis, Dermatomyositis, Polymyalgia Rheumatica, Acute Temporal Arteritis, Giant Cell Arteritis, Behcet s Disease, Sjorgren s Syndrome, Felty s Syndrome and Mixed Connective Tissue Disease (MCTD). Spondylarthritis (SpA) can be subdivided in Reactive Arthritis (ReA), Ankylosing Spondylitis (AS), Psoriatic Arthritis (PsA), Arthritis associated with the inflammatory bowel diseases are Crohn s disease and Ulcerative Colitis (IBD), Undifferentiated SpA (UspA) and Sacro-ilitis, Juvenile SpA and Acute Anterior Uveitis (AAU). 

The most frequent adverse reactions associated with the administration of proleukin include fever, chills, fatigue, malaise, nausea and vomiting. It has also been associated with capillary leak syndrome (CLS). CLS is defined as a loss of vascular tone and effusion of plasma proteins and fluids into the extravascular space. This leads to hypotension and decreased organ perfusion, which may cause sudden death. Other side effects include anaphylaxis, injection site necrosis and possible autoimmune and inflammatory disorders. 

An estimated 500,000 Americans have Crohn s disease, an inflammatory bowel syndrome (IBS) that causes chronic inflammation of the intestinal tract. Unlike many autoimmune diseases, Crohn s disease affects men and women equally. About 20% of people with Crohn s disease have a blood relative with some form of IBS. Crohn s disease and ulcerative colitis are similar and are often mistaken for one another. Both involve inflammation of the lining of the digestive tract, and both can cause severe bouts of watery or bloody diarrhea and abdominal pain. However, Crohn s disease can occur anywhere in the digestive tract, often spreading deep into the layers of affected tissues. Ulcerative colitis, on the other hand, usually affects only the Lining of the large intestine (colon) and rectum. 

Histologically, non-alcoholic steatohepatitis shows moderate to high-grade, mainly macrovesicular fatty degeneration of the liver cells with inflammatory infiltrates and formation of fibrosis. Cirrhosis frequently develops. Despite the morphological similarity to alcohol-induced fatty liver hepatitis, there is no (noteworthy) alcohol consumption involved in NASH. Viral or autoimmune hepatitis are not detectable either. There are no or only moderate subjective complaints. The transaminases are normal or slightly increased. NASH is mostly associated with obesity and/or type II diabetes, thus NASH is regarded as the hepatic manifestation of a metabolic syndrome. 

Reiter s Syndrome is an inflammatory arthritis that produces pain, swelling, redness and heat in the joints. It is one of a family of arthritic disorders, called spondylarthropathies, affecting the vertebral joints The symptoms of Reiter s disease include fever, weight loss, skin rash, inflammation, ulcerations, and pain. Unlike many autoimmune disorders, Reiter s syndrome usually affects young white men between the ages of 20 and 40. 

Te use of NSAIDS and other anti-inflammatory therapies are similar to those used in other autoimmune arthritic disorders. Corticosteroid injections for severe pain and inflammation at specific joints are standard therapy. For severe forms of the disease immunomodulating anti-rheumatic drugs such as methotrexate and sulfasalazine are effective. As with other similar disorders, the biologic TNF a inhibitors are currently prescribed for severe Reiter s syndrome. 

AID AIDP AIDS AIF AIRE AIS AES AMAN AMN AMPA AMSAN activation-induced (cytidine) deaminase acute inflammatory demyelinating polyradiculoneuropathy acquired immunodeficiency syndrome apoptosis inducing factor autoimmune regulator anterior chamber associated immune deviation (ACAID)-inducing signal amyotrophic lateral sclerosis acute motor axonal neuropathy adrenomyeloneuropathy a-amino-3 -hydroxy-5-methylisoxazole- 4-propionic acid acute motor-sensory axonal neuropathy... 

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