Aphthous stomatitis

Ocular complications (iritis, episcleritis, and conjunctivitis) occur in up to 10% of patients. Five percent to 10% of patients experience dermatologic or mucosal complications (erythema nodosum, pyoderma gangrenosum, aphthous stomatitis). 

Q59 Cigarette smoking should stop completely before starting varenicline. Varenicline may cause dry mouth, taste disturbance and aphthous stomatitis as side-effects. 

Varenicline is a selective nicotine receptor partial agonist that is used in smoking cessation. It is started 1-2 weeks before target stop date. It may cause gastrointestinal disturbances, dry mouth, taste disturbance and, less commonly, aphthous stomatitis. 

Orai uicerations Oral ulcerations may develop that may have the appearance of aphthous stomatitis. Although rare, cheilosis, glossitis, and gingivostomatitis have been reported. 

Nasal spray Bitter taste conjunctivitis epistaxis eye abnormality eye pain glossitis increased ALT nasal burning rhinitis paroxysmal sneezing taste loss temporomandibular dislocation ulcerative and aphthous stomatitis watery eyes. 

Ulcerating lesions Topical treatment of ulcerating lesions of the oral cavity, such as recurrent aphthous stomatitis (canker sores). 

Vitamin B complex preparations are indicated in vitamin deficiency states. Specific vitamin B preparations can be used as per indications mentioned above in the pharmacological write up as an adjuvant to antibiotic therapy combination with lactobacillus are indicated in aphthous stomatitis, thrush. 

Aphthae, recurrent aphthous stomatitis, periodontitis, gastritis, constipation. 

Site-specific drug delivery, which has the potential for local (topical) therapy of several conditions, such as aphthous stomatitis, gastric ulcer, esophageal cancer, toothache, and dental sores, as well as the potential for the treatment of systemic diseases such as diabetes mellitus and angina pectoris. ... 

A wide range of skin lesions has been reported, and most include skin dryness, rash, diffuse erythema, or urticaria, occurring in 5-12% of patients (20,281). However, severe dermatological complications are rare. In a prospective survey of 120 patients treated during 6-18 months for chronic viral hepatitis, only three developed lichen planus and one relapsing aphthous stomatitis (282). 

A convincing case of severe aphthous stomatitis has been reported in a patient receiving interferon gamma (SEDA-20, 333). 

Levamisole has been used in the treatment of recurrent aphthous stomatitis (2) and its value reviewed (3). In four of seven placebo-controlled studies there was a reduction... 

Stomatitis is a troublesome adverse effect of DMARDs. Ulcers of the oral mucosa are not uncommon in patients taking penicillamine (188,173) and lead to withdrawal in 3.1% of patients (174). However, stomatitis may be a consequence of multiple factors, including hematinic deficiency, virus or Candida infection, recurrent aphthous ulceration, or Sjogren s syndrome. Moreover, aphthous stomatitis often occurs in users of non-steroidal antiinflammatory drugs (175). 

In 58 Japanese patients with typhoid fever, 42 with paratyphoid fever, and one with both typhoid fever and paratyphoid fever, almost 80% of whom were treated with tosufloxacin, there were adverse effects (nausea, urticaria, aphthous stomatitis) in 3.6% and raised serum amylase in 8.3% (1). All the adverse reactions resolved with or without a change in drug therapy. 

Monoamine oxidase inhibitors are used to treat depression, atypical depression, bulimia, posttrau-matic stress reactions, obsessive-compulsive disorder, panic attacks, narcolepsy, phobias, hypochondria, anxiety, and many other psychiatric disorders as well as night tremors, parkinsonism, postural hypotension, headache, and aphthous stomatitis. 

Fitzgerald DA, Clin Exp Dermatol 18, 196 (passim) Aphthous stomatitis (<2%)... 

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