Antistress activities

Antistress activity. The leaf smoke, in combination with hashish smoke, administered to rats housed in a wire cage inside a larger cage with a cat, was equivocal. The... 

Throughout history, the root has been used as a treatment for asthenia, atherosclerosis, blood and bleeding disorders, colitis, and relief of symptoms associated with aging, cancer, and senility. Ginseng is also widely believed to be an aphrodisiac. It is promoted as a tonic capable of invigorating the user physically, mentally, and sexually. It is also said to have antistress activity (see Chapter 60 and page 95). 

Brassinosteroids (BSs) represent a new group of plant hormones that possess a broad spectrum of physiological activities (1,2). A most Intriguing property of BSs Is their capacity to Increase stress resistance In plants, but the mechanism of such an antistress activity still remains unknown (1). As cell stress resistance Is usually associated with stress protein synthesis (3 4) our aim was to study the BS effect on protein synthesis and ultrastructure of wheat leaf cells at normal temperature and under heat shock conditions. We have also studied the Influence of BSs on mesophyll cell ultrastructure under saline stress. 

Licorice has shown distinct antifatigue and antistress activity, and in vivo studies have shown strong activity against cancerous tumors and some protection from the effects of radiation. Perhaps it is best known for its estrogenic effects, which make it a useful herb for menopause, and its antiulcer activity, making it an herb of choice for both stomach and duodenal ulceration. Because it stimulates expectoration and is powerfully healing for mucous membrane systems, it has a long history of use for upper respiratory infections. 

Bhattacharya, S.K., R.K. Goel, R. Kaur, and S. Ghosal. 1987. Antistress activity of Sitoindosides VII and VIII, new acylsteryl-glucosides from Withania somnifera. Phytother. Res. 1 (l) 32-37. 

Patil M, Patki P, Kamath HV, Patwardhan B (1997) Antistress activity of Tinospora cordifolia (wild) Miers. Indian Drugs 34(4) 211-215... 

Neurotropic and antistress properties of 2,4-dimethylpyrido[l, 2-u]pyr-imidinium perchlorate were compared with those of piracetam (95MI7). AH-Pyrido[l,2-u]pyrimidin-4-one binds selectively to rat A3 receptors with a A", value of 48/xM. No affinities were observed to rat Ai and A2 receptors (96MI17). 4-Oxo-4//-pyrido[l,2-u]pyrimidine-3-carboxylic acid and -3-carbonitrile did not exhibit significant antibacterial activities (97MI6). 

Piccirillo et al. 1994). The effects of thromboxane A2 were examined in nondepressed, normai individuals. Thromboxane A2 was found to have direct CNS effects on hemodynamic, ACTH, and cortisol responses (Cudd 1998). Whether ginger has a significant effect on these processes and whether it has an antistress or antidepressant effect is speculative, but the eicosanoid activities of ginger and relationship to depression warrant further investigation. 

Antistress effect. Smoke of the dried leaf, administered to rats at variable doses, produced equivocal activity. Smoke, adminis-... 

Eleutherococcus senticosus (Rupr. ex Maxim.) Maxim. Ci Wu Jia (Siberian ginseng) (bark, root) Eleutherosides, beta-sitosterol glucoside, 1-sesamen, syringareinol.7-33 Central nervous system activating and antistress action. 

On the other hand, Fowler ef al. recently measured MAO-A and MAO-B activities in the human brain using positron emission tomography and ["CJdorgyline and ["C]L-deprenyl-D2, and showed that administration of EGb (120 mg/day, for 1 month) to 10 subjects had no influence on brain MAO-A and MAO-B [166]. Moreover, for the same dosages at which EGb (25, 50, and 100 mg/kg, p.o., for 5 days) exerted antistress properties, EGb did not exhibit any activity indicative of MAO inhibition in mice [167]. Therefore, there is uncertainty about whether MAO inhibition is the mechanism responsible for the anti-stress activity of EGb. This will be the subject of further study. 

Patil, R. A., S.C. Jagdale, and S.B. Kasture. 2006. Antihyperglycemic, antistress and nootropic activity of roots of Rubia cordifolia Linn. Indian J. Exp. Biol. 44(12) 987-992. 

Chowdhuri DK, Parmar D, Kakkar P, Shukia R, Seth PK, Srimal RC (2002) Antistress effects of bacosides of Bacopa monnieri modulation of Hsp70 expression, superoxide dismutase and cytochrome P450 activity in rat brain. Phytother Res 16 639-645... 

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