Ofloxacin antibacterial spectrum

Thus quinolone antibacterial agents, such as ciprofloxacin CPFX 143 [201], ofloxacin OFLX144 [202],sparfloxacin SPFX145 [203] and trovaflaxin 146 [204] are members of a major class of antibacterial drugs. These fluoroquinolones show broad-spectrum antibacterial activity and are widely used to treat patients with infections, Eq. (58). 

Ofloxacin. < )-9-Fluoro-2,3-dihydro-3-methyt-1Q-(4-methyi-l -piperazinyl)- 7-oxo-7H-py ridof 1,2,3-de -l,4-bemoxazine-6-carbiixylit acid ofloxacine DL-8280 HOE 280 Flobacln Floxin Oflocet oflocin Oxaldin Tarivid Visiren. C.jH FN mol wt 361.38. C 59.82%, H 5.58%, F 5.26%, N 11.63%, O 17-71%. Broad spectrum. Huorinated qulnolone antibacterial. Prepn . Hayakawa et al. Ear. 

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