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Anti-thymocyte

Anti thymocyte globulin Antitrypsin Anti tuberculin agents Antitumor activity... [Pg.65]

ANTI THYMOCYTE GLOBULINE ALLOWS FOR SUCESSFUL TRANSPLANTATION FROM HLA MISMATCHED UNRELATED DONORS... [Pg.263]

Anti-thymocyte globulin (ATG) is a purified immunoglobulin from horse, rabbit, sheep, or goat serum after immunization with human thymocytes. The administration of anti-thymocyte globulin results in a depletion of T-cells as a result of complement dependent lysis and opsonization by the macrophage-monocyte system. The depletion of CD4 positive cells is long lasting and results in an inversion of the CD4/CD8 ratio. There are hardly... [Pg.468]

Immune globulins anti-thymocyte globulin (equine)... [Pg.612]

Thymoglobulin, anti-thymocyte globulin (rabbit), purified rabbit IgG against human thymocytes... [Pg.475]

Parenteral 30 mg/3 mL vial for IV injection Anti-Thymocyte Globulin (Thymoglobulin)... [Pg.1359]

Anti-thymocyte globulin (rabbit) selective depletion of T cells... [Pg.958]

Okuda et al. (1990) provided evidence of an elevated expression of transforming growth factor-, proteoglycans and fibronectin in glomerulonephritis induced in rats by injection of anti-thymocyte serum. [Pg.130]

Immuno globulins (IG) pertusssis IG, rabies IG, tetanus IG, hepatitis B IG, varicella zoster IG, rho(D) IG, normal immune globulin, lymphocyte anti-thymocyte, IB (equine)... [Pg.36]

Jocks T, Zahner G, Freudenberg J, Wolf G, Thaiss F, Helmchen U, Stahl RA Prostaglandin El reduces the glomerular mRNA expression of monocyte- chemoattractant protein 1 in anti-thymocyte antibody-induced glomerular injury. J Am Soc Nephrol... [Pg.221]

Thymoglobulin (ATG) Anti-thymocyte globulin - Acute kidney and liver allograft rejection - Acute renal failure 110,111... [Pg.684]

Anti-thymocyte globulin (ATG, thymoglobulin) is a polyclonal rabbit antithymocyte globulin that has been used as an immunosuppressive agent in kidney and hver transplant patients. Despite a fairly high safety profile, reported side effects of ATG include hypertension, leucopenia and ARDS [109]. Renal adverse effects are extremely rare only two case reports describe the occurrence of acute renal failure in patients treated with ATG [110, 111]. Cessation of ATG therapy in both cases and plasmapheresis in one case resulted in full recovery. [Pg.693]

AHS aUopurinol hypersensitivity syndrome ATG anti-thymocyte globulin... [Pg.945]

France anti-thymocyte globulin antibody Thymo- globuline Thymoglobulin Polyclonal rabbit antithymocyte antibodies Immuno- suppressant... [Pg.460]

Anti-TAP-72 immunotoxin Antithrombin III Anti-thymocyte serum Antivenin Apomorphine HCl Aprotinin... [Pg.519]

Lymphocyte immune-, anti -thymocyte-globulin (Atgam) Horse IgG antibodies which selectively suppress T-lymphocytes (cell-mediated immunity) and humoral immunity. Prevention of organ transplant rejection, aplastic anemia. Fever, chills, leukopenia, throm -bocytopenia, skin reactions. Less often arthralgia, chest or back pain, dyspnea, nausea, vomiting, headache, night sweats (serum sickness). [Pg.138]

A8 Andersson, J. and Darzynkiewicz, Z. Nucleoprotein changes and uridine incorporation in rat thymus lymphocytes. I. Cellular characterization of age-dependent thymus involution. II. Effect of treatment with anti-thymocyte serum in vitro. Exp. Cell Res., 75, 410-416 417-423 (1972)... [Pg.49]

Finally, Wenzel et al. (20) examined the role of MCP-1 in an anti-thymocyte antiserum-induced model of GN. Using a neutralizing polyclonal antiserum against rat MCP-1, they demonstrated a significant reduction in macrophage, but not neutrophil, infiltration into the glomeruli 24 h after induction of disease. In addition, the monocyte chemotactic activity present in conditioned medium from inflamed glomeruli was reduced to control values in rats treated with the anti-MCP-1 serum. [Pg.55]

Wenzel, U., Schneider, A., Valente, A. J., Abboud, H. E., Thaiss, F., Helmchen, U. M., and Stahl, R. A. K. (1997) Monocyte chemoattractant protein-1 mediates monocyte/macrophage influx in anti-thymocyte antibody-induced glomerulonephritis. Kidney Int. 51,116-llf>. [Pg.63]

Park SH, Choi SM, Lee DG, Choi JH, Yoo JH, Kim SH, Kim HJ, Cho SG, Eom KS, Lee JW, Min WS, Shin WS, Kim CC. Infectious comphcations associated with alemtuzumab use for allogeneic hematopoietic stem cell transplantation comparison with anti-thymocyte globuhn. Transpl Infect Dis 2009 11(5) 413-23. [Pg.600]

Indicated and approved for the management of allograft rejection in renal transplant patients, antithymocyte globulin preparations are purified immune globulins (primarily IgG) from horses or rabbits immunized with human thymus lymphocytes. The resultant globulin preparations contain cytotoxic antibodies to human T lymphocytes which function as an immunosuppressive agent. As well as its use for the treatment of renal transplant rejection, anti-thymocyte globulin may be administered as an adjunct to other immunosuppressive... [Pg.382]

See other pages where Anti-thymocyte is mentioned: [Pg.1228]    [Pg.465]    [Pg.468]    [Pg.767]    [Pg.1721]    [Pg.1727]    [Pg.692]    [Pg.693]    [Pg.87]    [Pg.87]    [Pg.717]    [Pg.56]    [Pg.439]    [Pg.511]    [Pg.1]    [Pg.369]    [Pg.382]    [Pg.382]   
See also in sourсe #XX -- [ Pg.465 ]

See also in sourсe #XX -- [ Pg.87 ]



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