Anti-allergies

Desired effects. As anti-allergies, immunosuppressants, or anti-inflammatory drugs, glucocorticoids display excellent efficacy against undesired inflammatory reactions. 

Hydrocortisone exhibits anti-shock, anti-allergy, and anti-inflammatory action. It raises sugar content in the blood, increases potassium secretion, and lowers sodium excretion from the body. It exhibits anti-metaboUc action and reduces histamine synthesis in the body. 

Assay for Anti-Inflammatory and Anti-Allergie Compounds ... 

Farooqui A. A., Ong W. Y., Lu X. R., and Horrocks L. A. (2002). Cytosolic phospholipase A2 inhibitors as therapeutic agents for neural cell injury. Curr. Med. Chem. - Anti-Inflammatory Anti-Allergy Agents 1 193-204. 

Potential anti-allergy botanicals were first identified from the medical and eth-nopharmacological literature, from botanical products currently marketed around the world for allergy symptoms, and from discussions with raw-material suppliers. This produced a list of about 70 plant dehydrates, concentrates, or extracts. The potential ingredients were submitted to bioassay screening and regulatory review to narrow the potential active ingredients. 

A series of bioassays was utilized to screen a variety of single and combination botanical compounds for anti-allergy action in vitro. A combination of three ingredients—Herbal Blend—showed apparent synergistic inhibition of histamine. However, in vitro efficacy against allergic mediators does not ensure effectiveness in native disease—that is, in allergy sufferers in daily life. In addition, the commercial... 

Spanish needles have also been found to have anti-allergy action at the level of mast cells and other allergy mediators.4 Spanish needles contains quercetin and ethyl caffeate, both of which have previously been shown to possess in vitro anti-inflammatory or anti-allergic mediator action.23,24 Quercetin5 has also been shown to stabilize mast cells and basophils, decrease leukotriene formation, and reduce release of histamine and other mediators.24,25 Anti-inflammatory effects have been demonstrated in rats after receiving aqueous extracts of Spanish needles leaves and stems.26,27 A related species, Bidens parviflora, has been reported to inhibit histamine release from rat mast cells in vitro.6 Spanish needles have been shown to inhibit the inflammatory mediator nuclear transcription factor kappaB (NF-kappaB) and its downstream inflammatory mediators in vitro.23... 

GRAPEFRUIT JUICE ANTIHISTAMINES/ANTI-ALLERGY DRUGS ... 

Category Cs vaccinations and anti-allergies are included in this category. The co-payment is 60 percent. 

Bronchodilating Agents, Cards 177-180 Mucolytic/Expectorant Agents, Cards 181-182 Anti-Allergy/Anti-Inflammatory Agents, Cards 183-185... 

The oligosaccharides prepared from alginate can exhibit a variety of biological activities, including anti-allergy properties, anti-hypertensive activity, an ability to enhance the growth of human endothelial cells and keratinocytes, and an ability to induce cytokine production [157]. 

Sleeping pills Most of these have anti-allergy components that can cause sleepiness. 

Maccarrone, M., Van der Stelt, M., Veldink, G.A., and Finazzi-Agro, A. (2002) Inhibitors of endocannabinoid degradation as potential therapeutic agents. Current Medicinal Chemistry — Anti-Inflammatory and Anti-Allergy Agents V. 103-113. 

The anti-allergy drugs, cromolyn sodium and lodoxamide tromethamine show in vitro dose responses which are bell-shaped or biphasic in mast cells. The nature of the biphasic dose response is poorly understood however, through the use of specific antagonists it has been possible to show that at the high concentrations of these drugs leading to enhanced histamine release or... 

These results are consistent with the hypothesis, that this unwanted effect of the anti-allergy drug occurs throu a cholinergic receptor leading to the accumulation of cGMP in the cells. 

Filarial nematodes also secrete a glycoprotein call ES-62 with anti-allergy properties. It directly inhibits FceRI induced release of mediators from human and rodent mast cells. It forms a complex with TLR4 resulting in cellular depletion of protein kinase C-a, a molecule important for FceRI signaling, thus preventing mast cell degranulation in response to IgE. ... 

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