Spanish needles

The Herbal Blend, composed of equal parts by weight of cinnamon bark extract (Cinnamomum zeylanicum), acerola fruit (Malpighia glabra), and Spanish needles powder (Bidens pilosa), was one of the first combination formulas assayed. Surprisingly, it showed synergistic inhibition of histamine release The sum of the inhibition of the three ingredients was 10.2% of control, whereas their combination inhibited histamine release to -52% (i.e., to below the concentration of histamine found in unstimulated cells). 

Spanish needles have also been found to have anti-allergy action at the level of mast cells and other allergy mediators.4 Spanish needles contains quercetin and ethyl caffeate, both of which have previously been shown to possess in vitro anti-inflammatory or anti-allergic mediator action.23,24 Quercetin5 has also been shown to stabilize mast cells and basophils, decrease leukotriene formation, and reduce release of histamine and other mediators.24,25 Anti-inflammatory effects have been demonstrated in rats after receiving aqueous extracts of Spanish needles leaves and stems.26,27 A related species, Bidens parviflora, has been reported to inhibit histamine release from rat mast cells in vitro.6 Spanish needles have been shown to inhibit the inflammatory mediator nuclear transcription factor kappaB (NF-kappaB) and its downstream inflammatory mediators in vitro.23... 

Corunnine (127) (73JCS(CC)915) was isolated as violet needles in the course of studies of Spanish Papaveraceae, i.e., Glaucium flavum Cr. var. vestitum (71TL3093). The UV absorption maxima kmax of Corunnine are very similar in ethanol and hydroxide solutions and were found at... 

Spanish oak. Wood chips prepared from small wood, branches and bark, without included green parts (needles). 

Bone Felon. The following receipt for tho cure of bone felon is given by that high authority, the London Lancet As soon as the disease is felt, put directly over tho spot a blister of Spanish nv, about tho size of tho thumb nail, and let it remain for 6 hours, at tho expiration of which time, directly under the surface of the blister may be seen the felon, which can be instantly t en out with tho point of a needle or a lancet. 

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