Bone cyst, aneurysmal

Rastogi, S., Varshney, M.K., Trikha, V., Khan, S.A., Choudhury, B., Safaya, R. 2006. Treatment of aneurysmal bone cysts with percutaneous sclerotherapy using polidocanol A review of 72 cases with long-term follow-up. J Bone Joint Surg Br 88-B(90), 1212-1216. 

Fig. 21.8a,b. Aneurysmal bone cyst. Pathological fracture through the ABC in the proximal humerus in the active phase. The axial T2-weighted MR image shows multiple fluid-fluid levels... 

Cottalorda J, Bourelle S (2006) Current treatments of primary aneurysmal bone cyst. J Pediatr Orthop 15B 155-167... 

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Comparative studies Percutaneous repetitive sclerotherapy with polidocanol has been compared with intralesional excision and bone grafting in the treatment of aneurysmal bone cysts in 94 patients [57 ]. Complications of sclerotherapy were minor and resolved, while three of those who had surgery developed deep infections, five had superficial infections, and two had growth disturbances. Intralesional excision was also associated with higher rates of clinically important complications, worse functional outcomes, and a higher hospital burden. 

Varshney MK, Rastogi S, Khan SA, Trikha V. Is sclerotherapy better than intra-lesional excision for treating aneurysmal bone cysts Clin Orthop Relat Res 2010 468(6) 1649-59. 

In 2001, about 2,900 new cases of cancer of the bones and joints were diagnosed, and about 1,400 deaths from these cancers were expected. Primary cancers of bones account for less than 0.2% of all cancers. Regional management options consisting of intraarterial chemotherapy and arterial embolization have been used with favorable results in the treatment of osteosarcoma, unre-sectable giant cell tumors, and aneurysmal bone cysts. 

Aneurysmal bone cyst (ABC) is a benign lesion of the bone that presents most frequently in the pediatric population. The most common site of involvement is the metaphysis of long bones with the axial skeleton being involved to a lesser degree. ABCs tend to grow rapidly with 84% having destroyed more than half of the bone width at initial presentation. ABCs can be either primary or secondarily associated with osteoblastomas, giant-cell tumors, and osteosarcomas. The incidence of secondary ABC is 23% (Szendroi et al. 1992). 

Embolization Selective arterial embolization has been utihzed as an adjunct to surgical curettage and bone grafting, but has also been effective as a stand-alone intervention. De Cristofaro et al. (1992) reported their experience with selective arterial embolization in a series of 19 patients with aneurysmal bone cysts and five patients with angiomas of bone. In total, 17 patients demonstrated healing with complete relief... 

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Chuang VP et al. (1981a) Arterial occlusion management of giant cell tumor and aneurysmal bone cyst. AJR Am J Roentgenol 136 1127-1130... 

De Cristofaro R et al. (1992) Selective arterial embolization in the treatment of aneurysmal bone cyst and angioma of bone. Skeletal Radiol 21 523-527 Diamandidou E et al. (1998) Two-phase study of hepatic artery vascular occlusion with microencapsulated cisplatin in patients with liver metastases from neuroendocrine tumors. AJR Am J Roentgenol 170 339-344 Dick HM et al. (1979) Adjuvant arterial embolization in the treatment of benign primary bone tumors in children. Clin Orthop 139 133-341... 

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Szendroi M et al. (1992) Aneurysmal bone cyst A review of 52 primary and 16 secondary cases. Arch OrthoTrauma Surg 111 318-322... 

Goldenberg DL (1998) Septic arthritis. Lancet 351 197-202 GomezJ.Pinar A,VallcaneraAetal (1998) Sonographic findings in aneurysmal bone cyst in children correlation with computer tomography findings. J Clin Ultrasound 26 59-64... 

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