Allergy allergic rhinitis

The efficacy of subcutaneous SIT has been clearly shown in a metaanalysis of 43 double-blind placebo-controlled trials in allergic rhinitis as well as another meta-analysis of 16 double-blind placebo-controlled studies in asthma patients [13]. The mean clinical improvement was 45% reduction in symptoms and medication compared with placebo in rhinitis and 40% in asthma patients, which exceeds the effects of drug therapy. A recent meta-analysis also confirmed that asthma responds favorably to SIT [14], However, recently it could also be demonstrated that SIT is effective in patients with house dust mite allergy, allergic rhinitis and asthma [15]. Immunotherapy in these patients not only reduced rhinitis and asthma symptoms as well as rescue medication, but also had an impact on bronchial hyperreactivity over the 3-year follow-up period. 

Diphenhydramine (Benadryl) Dimenhydrinate (Dramamine) Carbinoxamine (Clistin) H1 Receptor Antagonist Type I allergies (allergic rhinitis conjunctivitis, simple urticaria, pruritis, angioedema). To induce sleep. Sedative VARIABLE Anticholinergic HIGH Gl upset LOW... 

MH, Townley RG. Mokhtarani M. Seyfert-Margohs V, Asare A. Bateman K. Deniz Y Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis. J Allergy Clin Immunol 2006 117 134-140. 

Adapted from American Academy of Allergy.3 (From May JR, Smith PH. Allergic Rhinitis. In DiPiro JT, Talbert RL, Yee GC, et al, (eds.) Pharmacotherapy A Pathophysiologic Approach. 6th ed. New York McGraw-Hill 2005 1734, with permission.)... 

Transgrund AJ, Whitaker AL, Small RE. Intranasal corticosteroids for allergic rhinitis. Pharmacotherapy 2002 22 1458-1467. van Cauwenberge P, Bachert C, Passalacqua G, et al. Consensus statement on the treatment of allergic rhinitis. Allergy 2000 55 116-134. 

T. B. Casale, S. M. Azzum, R. E. Miller, and J. Oren, Demonstration of therapeutic equivalence of generic and innovator beclomethasone in seasonal allergic rhinitis, Ann. allergy Asthma Immunol, 82, 435 (1999). 

The patient may have a family history of allergy or asthma or have symptoms of allergic rhinitis. A history of exercise or cold air precipitating dyspnea or increased symptoms during specific allergen seasons also suggests asthma. 

Baena-Cagnani CE, Passalacqua G, Gomez M, Zernotti ME, Canonica GW New perspectives in the treatment of allergic rhinitis and asthma in children. Curr Opin Allergy Clin Immunol 2007 7 201-206. 

Baena-Cagnani CE, Berger WE, Du-Buske LM Comparative effects of desloratadine versus montelukast on asthma symptoms and use of (Jj agonists in patients with seasonal allergic rhinitis and asthma. Int Arch Allergy Immunol 2003 130 307-313. 

Simons FER Allergic rhinobronchitis the asthma/allergic rhinitis link. J Allergy Clin Immunol 1999 104 543-537. 

Kleinjan A, Willart M, van Rijt LS, Braunstahl GJ, Leman K, Jung S, Hoogsteden HC, Lambrecht BN An essential role for dendritic cells in human and experimental allergic rhinitis. J Allergy Clin Immunol 2006 118 1117-1125. 

Holm AF, Fokkens WJ, Godthelp T, Mulder PG, Vroom TM, Rijntjes E Effect of 3 months nasal steroid therapy on nasal T cells and Langerhans cells in patients suffering from allergic rhinitis. Allergy 1995 50 204-209. 

Meltzer, E. O., Malmstrom, K., Lu, S., et al. (2000) Concomitant montelukast and loratadine as treatment for seasonal allergic rhinitis a randomized, placebo-controlled clinical trial. J. Allergy Clin. Immunol. 105, 917-922. 

Chlorpheniramine reduces the allergic response of the organism caused by histamine. It is nsed for allergy symptoms, rhinitis, and also as an ingredient in numerons compositions with ephedrine and pseudoephedrine, which are recommended for colds, npper respiratory... 

Wilson DR, Lima MT, Durham SR. Sublingual immunotherapy for allergic rhinitis systematic review and meta-analysis. Allergy 2005 60(1) 4-12. Review. 

The synthesis of selective CRTH2 receptor antagonists has been more extensively studied to develop them as potential clinical candidates for the treatment of allergy, asthma, or other inflammatory disorders (Fig. 10). Ramatroban, a TP receptor antagonist, clinically used in asthma and allergic rhinitis, was recently... 

Mahakit. Aeroallergen sensitivity of Thai patients with allergic rhinitis. Asian Pac J Allergy Immunol 1997 15(4) 183-185. 

Klein GL, Littlejohn T, Lockhart EA, et aL Brompheniramine, terfenadine, and placebo in allergic rhinitis. Ann Allergy Asthma Immunol 1996, 77 365-370. 

The newer antihistaminics agents e.g. Azelastme inhibits histamine release and also inflammatory reactions evoked by leukotrienes and plasma activating factor (PAF). It is used for seasonal and perennial allergic rhinitis in the form of nasal spray. Mizolastine, a non-sedating antihistaminic is used in allergic rhinitis and urticaria. Ebastine, another non-sedating antihistaminic is used in nasal and skin allergies. 

Howarth PH, Salagean M, Dokic D. 2000. Allergic rhinitis Not purely a histamine-related disease. Allergy, 55 7-16. 

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