House dust mites

CM Topham, N Snmvasan, CJ Thorpe, IP Ovenngton, NA Kalsheker. Comparative modelling of major house dust mite allergen der p I Structure validation using an extended environmental ammo acid propensity table. Protein Eng 7 869-894, 1994. 

An allergen is usually an inert substance (e.g. pollen, house dust mite faeces) that in some individuals can trigger the generation of an (inappropriate) antigenic response. Mediated by TH2 lymphocytes, it causes B-Lymphocytes to produce lgE. Subsequent exposure of a sensitized individual to the allergen is therefore able to cross-link IgE antibodies on the surface of mast cells and trigger an immune response and histamine release. 

Van der Veen MJ. Mulder M. Witteman AM. van Ree R. Aalberse RC. Jansen HM. van der Zee JS False-positive skin prick test responses to commercially available dog dander extracts caused by contamination with house dust mite (Dermatophagoides pteronyssimus) allergens. J Allergy Clin Immunol 1996 98 1028-1034... 

Reduce indoor humidity to less than 50% if possible House dust mites... 

Wang CR, Chen PC, Liu MF. Increased circulating CCR3+ type 2 helper T cells in house dust mite-sensitive Chinese patients with allergic diseases. Asian Pac J Allergy Immunol 2003 21(4) 205-210. 

Lambert, A.L., et al., Residual oil fly ash exposure enhances allergic sensitization to house dust mite, Toxicol. Appl. Pharmacol., 158, 269, 1999. 

Greiff L, Andersson M, Svensson J, Wollmer P, Lundin S, Persson CGA (2002) Absorption across nasal airway mucosa in house dust mite perennial allergic rhinitis. Clin Physiol Funct Imaging 22 55-57. 

Winton HL, Wan H, Cannell MB, Gruenert DC, Thompson PJ, Garrod DR, Stewart GA, Robinson C (1998) Cell lines of pulmonary and non-pulmonary origin as tools to study the effects of house dust mite proteinases on the regulation of epithelial permeability. Clin Exp Allergy 28 1273-1285. 

Yu CK, Chen CL Activation of mast cells is essential for development of house dust mite Dermatophagoides farinae-mduced allergic airway inflammation in mice. J Immunol 2003 171 3808-3815. 

Cates EC, Fattouh R, Wattle J, et al Intranasal exposure of mice to house dust mite elicits allergic airway inflammation via a GM-CSF-mediated mechanism. J Immunol 2004 173 6384-6392. 

Werfel T, Breuer K, Rueff F, Przybilla B, Worm M, Grewe M, Ruzicka T, Brehler R, Wolf H, Schnitker J, Kapp A Usefulness of specific immunotherapy in patients with atopic dermatitis and allergic sensitization to house dust mites a multicentre, randomized, dose-response study. Allergy 2006 61 202-205. 

Langer K, Breuer K, Kapp A, Werfel T Staphylococcus aureus-derived entero-toxins enhance house dust mite-induced patch test reactions in atopic dermatitis. Exp Dermatol 2007 16 124-129. 

Bussmann C, Maintz L, Hart J, Allam JP, Vrtala S, Chen KW, Bieber T, Thomas WR, Valenta R, Zuberbier T, Sager A, Novak N Clinical improvement and immunological changes in atopic dermatitis patients undergoing subcutaneous immunotherapy with a house dust mite allergoid a pilot study. Clin Exp Allergy 2007 37 1277-1285. 

Tropomyosin is a protein found in vertebrates and invertebrates, but only the protein from invertebrates has allergic properties. It is frequently found in sea foods, such as shrimps, crabs, American lobsters. Pacific flying squids, and also in some species of cockroaches (Blattela germanica, Periplaneta americand), moths, spiders, and house dust mites (Dermatophagoides pteronyssinus, Dermatophagoides farinae) (Witteman et ah, 1994). 

Dust has been recognised as a trigger for asthma for many years and the allergens are present in the faeces of the house dust mite, of genus Dermatophagoides. They are members of the order Arachnida (close relatives of ticks and spiders). They live off human skin that has been shed and hence are present in bedding and carpets. Since they are not visible to the naked eye and are difficnlt to control, they can be overlooked as the canse of this distressing disease. They may also be a cause of perennial rhinitis and atopic dermatitis. 

Azofra, J., and Lombardero, M. (2003). Limpet anaphylaxis Cross-reactivity between limpet and house-dust mite Dermatophagoides pteronyssinus. Allergy 58,146-149. 

Caiado, J., Lundberg, M., Oman, H., Pedro, E., Pereira-Santos, M., and Periera Barbosa, M. (2007). Isolated snail allergy without house dust mites sensitisation Case report. Allergy 62(Suppl. 83), 218. 

DeMaat-Bleeker, F., Akkerdas, J. H., VanRee, R., and Aalberse, R. C. (1995). Vineyard snail allergy possibly induced by sensitization to house dust mite. Ann. Allergy 50, 438-440. 

Guilloux, L., Vuitton, D. A., Delbourg, M., Lagier, A., Adessi, B., Marchand, C. R., and Ville, G. (1998). Cross-reactivity between terrestrial snails (Helix species) and house-dust mite (Dermatophagoides pteronyssinus). 11. In vitro study. Allergy 53,151-158. 

Mistrello, G., Falagiani, P., Riva, G., Gentili, M., and Antonicelli, L. (1992). Cross-reactions between shellfish and house-dust mite. Allergy 47, 287. 

Peroni, D. G., Piacentini, G. L., Bodini, A., and Boner, A. L. (2000). Snail anaphylaxis during house dust mite immunotherapy. Pediatr. Allergy Immunol. 11, 260-261. 

Sidenius, K. E., Hallas, T. E., Poulsen, L. K., and Mosbech, H. (2001). Allergen cross-reactivity between house-dust mites and other invertebrates. Allergy 56, 723-733. 

Reka, S. A., Suto, C. and Yamaguchi, M. (1992). Evidence of aggregation pheromone in the feces of house dust mite, Dermatophagoides farinae. Japanese Journal of Sanitary Zoology 43 339-341. 

Hydroxy-6-methylbenzaldehyde the female sex pheromone of the house dust mite Dermatophagoides farinae (Astigmata Pyroglyphidae). Japanese Journal of Sanitary Zoology 52 269-277. 

Tongu, Y., Ishii, A. and Oh, H. (1986). Ultrastructure of house-dust mites,... 

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