Acid Diethylamide LSD

technically it s lysergic acid diethylamide, or just acid . It s also known as LSD25, or colloquially as cubes, pearly gates, heavenly blue, royal blue, wedding bells, sugar, sugar lump, big D, blue acid, the chief, the hawk, instant Zen, etc. 

I ll Stick to LSD. How Long Have People Known ABOUT It  

Rye infected by ergot. The ergot kernel is the darker husk drooping down from the ear of rye 

Since the sixteenth century, ergot has had medicinal uses, originally to induce contractions and bring about childbirth. 

In 1938, the Swiss chemist Albert Hofmann, made an ergotamide drug to be used to stop bleeding during childbirth. It was given the code name LSD-25 as it was the 25th lysergic acid derivative synthesized by Hofmann. 

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Buckholtz NS, Zhou DF, Freedman DX, et al Lysergic acid diethylamide (LSD) administration selectively downregulates serotonin2 receptors in rat brain. Neuropsychopharmacology 3 137-148, 1990... 

Cohen S, Ditman K Complications associated with lysergic acid diethylamide (LSD-25). JAMA 181 161-162, 1962... 

Some neuroleptics, including clozapine, are potent 5-HT-receptor antagonists and the possible role of 5-HT in the action of neuroleptics and the development of schizophrenia has recently generated much interest (Busatto and Kerwin 1997). This has centred primarily on 5-HT2A receptors found in the limbic cortex, which are linked to neuronal excitation and believed to mediate the hallucinogenic effects of drugs such as lysergic acid diethylamide (LSD). 

Flirschhom, I, and Winter, J.C. Mescaline and lysergic acid diethylamide (LSD) as discriminative stimuli. Psychopharmacologia 22 64-71, 1971. 

Buspirone, lithium, and ergot alkaloids ° Lysergic acid diethylamide (LSD)... 

As it can be observed in Fig. 2, three out of the 16 investigated compounds, namely, heroin, lysergic acid diethylamide (LSD), and its metabolite 2-oxo, 3-hydroxy-LSD (O-H-LSD), were not detected in any wastewater sample. Two other target analytes, 6-acetyl morphine (6ACM) and A9-tetrahydrocannabinol (THC), were only present in influent wastewaters and with low detection frequencies. The most ubiquitous compounds, present in all influent and effluent wastewater samples analyzed, were the cocaine metabolite benzoylecgonine, and the amphetamine-like compounds ephedrine (EPH) and 3,4-methylenedioxymethamphetamine (MDMA or ecstasy). Cocaine, cocaethylene (CE, transesterification product of cocaine formed after the joint consumption of cocaine and ethanol), and morphine (MOR) were detected in all influent, but not in all effluent wastewaters (see Fig. 2). 

Nelson CC, Foltz RL (1992) Chromatographic and mass spectrometric methods for determination of lysergic acid diethylamide (LSD) and metabolites in body fluids. J Chromatogr Biomed Appl 580 97-109... 

Phencyclidine (PCP) (angel dust, crystal) is often misrepresented as lysergic acid diethylamide (LSD) or THC. It is commonly smoked with marijuana (crystal joint) but can be taken orally or IV. 

Davis, M., Gallager, D. W., and Aghajanian, G. K. (1977) Tricyclic antidepressant drugs Attenuation of excitatory effects of d-lysergic acid diethylamide (LSD) on the acoustic startle reflex. Life Sci., 20 1249-1258. 

Davis, M., and Sheard, M. H. (1974) Effects of lysergic acid diethylamide (LSD) on habituation and sensitization of the startle response in the rat. Pharmacol. Biochem. Behav., 2 675-683. 

Haigler, H. J., and Spring, D. D. (1979) Drugs that antagonize limb Oick behavior induced by d-lysergic acid diethylamide (LSD) in cats. Psychopharmacology, 64 31-34. 

Bennett, J. P., Jr., and Snyder, S. H. (1975) Stereospecific binding ofD-lysergic acid diethylamide (LSD) to brain membranes Relationship to serotonin receptors. Brain Res., 94 523-544. 

White, F. J., and Appel, J. B. (1982) Lysergic acid diethylamide (LSD) and lisuride Differentiation of their neuropharmacological actions. Science, 216 535-537. 

Isbell, H., Logan, C. R., and Miner, E. J. (1959) Studies on lysergic acid diethylamide (LSD-25). III. Attempts to attenuate the LSD-reaction in man by pretreatment with neurohumoral blocking agents. Arch. Neurol. Psychiatry, 81 20-27. 

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