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Vitamins solubilizing agents

Polyoxyl 35 castor oil is mainly used as an emulsifing and solubilizing agent, and is particularly suitable for the production of aqueous liquid preparations containing volatile oils, fat-soluble vitamins, and other hydrophobic substances. Cremophor EL emulsifies or solubilizes the fat-soluble vitamins A, D, E, and K in aqueous solutions for oral and topical administration. In 1 mL of a 25% v/v aqueous polyoxyl 35 castor oil (Cremophor EL) solution it is possible to incorporate approximately 10 mg of vitamin A palmitate approximately 10 mg of vitamin D approximately 120 mg of vitamin E acetate or approximately 120 mg of vitamin Kj. [Pg.573]

Vitamin Bi Thymol blue, bromothymol blue. Over the range 1 1 solubilization agents ... [Pg.4521]

Uses Emulsifier, stabilizer, opacifier, vise, builder In foods, cosmetics, phannaceu-ticals (vitamin carrier, ointment and cream bases) dispersant and solubilizing agent for flavors, essential oils and vitamins Regulatory FDA 21 CFR 175.300,175.320,184.1323 (GRAS) kosher Properties Gardner 6 liq. mild, fatty odor sp. gr. 0.94 vise. 92.0 cps (100 F) HLB 3.4 iodine no. 78 sapon. no. 168 flash pt. 239 C 40-45% cone. [Pg.371]

A surfactant is a surface-active agent that is used to disperse a water-insoluble drug as a colloidal dispersion. Surfactants are used for wetting and to prevent crystal growth in a suspension. Surfactants are used quite extensively in parenteral suspensions for wetting powders and to provide acceptable syringability. They are also used in emulsions and for solubilizing steroids and fat-soluble vitamins. [Pg.394]

Chem. Descrip. Dioctyl sodium sulfosuccinate USP CAS 577-11-7 EINECS/ELINCS 2094064 Uses Surfactant for pharmaceuticals, foods, and cosmetics wetting agent, solubilizer, dispersant, emulsifier for tablets, tablet coating, treatment of constipation (alone or with other laxatives), topical creams, lotions, and ointments, vitamins, ear wax removal solubilizer for dyes, chlorophyll, bile acids... [Pg.269]

Uses Lubricant, emulsifier in lubricants for plastics, metals, textiles clay/ pigment dispersant, rewetting agent, softener, dyeing assistant for paints, paper, textiles, and leather surfactant, emulsifier in cosmetics, pharmaceuticals solubilizer for essential oils, vitamins, and pharmaceuticals in food-pkg. adhesives Regulatory FDA 21CFR 175.105,175.300,177.2800... [Pg.1247]

Uses Emulsifier in cosmetics, prep, of o/w emulsions solubilizer for flavors, perfumes, vitamin oils dispersant antistat refatting agent for hair/bath preps. in resinous/polymeric food-contact coatings in food-contact textiles... [Pg.3126]

Uses Emulsifier, solubilizer, lubricant for flavors, vitamins, textiles, household formulations, suppositories (pharmaceuticals), emulsion polymerization, hydraulic fluids, metal treatment, paints color dispersant for plastics, cosmetics, leather emulsifier in cosmetics lubricant for fibers antistat stabilizer vise, modifier suspending agent in resinous/polymeric food-contact coatings... [Pg.3568]

Properties Sol. in alcohol, min. oil sp.gr. 0.921 flash pt. (COC) 159 C ref. index 1.4350 Uses Emollient for cosmetics, creams/lotions, topicals, makeup, bath preps., after-shave lotions plasticizer solvent, carrier, vehicle in flavors, fragrances, vitamins, antibiotics, medicinals vehicle for nutritional prods. emollient, moisturizer, lubricant, penetrant, extender, carrier, vehicle, solvent, solubilizer, fixing agent, humectant in pharmaceuticals, dermatologicals, dry skin prods., suppositories... [Pg.3747]

Uses Emulsifier, antibacterial, wetting agent, dispersant for cosmetics, foods, pharmaceuticals lubricant, disintegrant, binder, filler for tablets anticaking agent solubilizer, stabilizer for fat-sol. vitamins and antibiotics... [Pg.4253]

Uses Emollient, solvent, vise, control agent, lubricant, emulsifier for cosmetics lubricant, emulsifier for metals, leather, textiles carbon source in antibiotic culture broths raw material for engineering plastics impact modifier plasticizer stabilizer solvent for carbon paper, printing ink dyes food emulsifier, stabilizer solubilizer for flavors, vitamin oils pharmaceutical lubricant, emollient, solubilizer, stabilizer in food-contact textiles... [Pg.4583]

Nicotinamide, or vitamin B3, characterized by a low toxicity, has been proven to solubilize a number of drugs, such as, for example, riboflavin (35) and nifedipine (36). A 36-fold increase of the solubility of riboflavin, which has a multi-aromatic ring system, at nicotinamide concentrations of about 2M, has been observed (35). It has been shown that complexation occurs between the riboflavin and the hydrotropic agents cytosine and caffeine, respectively (35). However, in the case of nicotinamide, no evidence for complexation between riboflavin and nicotinamide. [Pg.418]


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