Under-correction

Exposure and development must be predictable and repeatable because multiple pieces of film may be used for a single plate exposure. The proper exposure source and the intensity of that source must be estabUshed. The imagesetter must be properly linearized to produce the desired precise halftone dots. This film must be handled under correct safelight conditions and machine-processed in chemical developers at the correct speed and temperature. 

The polymer has a good melt thermal stability. It is claimed that up to 100% regrind may be used. Under correct processing conditions the polymers have been shown to produce samples with little change in physical properties even after seven regrinds. 

Any saturated vapor can be condensed by a direct spray of cold water under correct temperature and pressure. If sufficient contact is provided, coolant and vapor will reach an equilibrium temperature. The condensate created by the water should not be objectionable in its liquid form. 

The standard does not make it clear whether these requirements apply to nonconformities detected while the supplier is responsible for the product or after the supplier s responsibility ceases, as is the case with nonconformity reports received from customers. Reports of nonconformities are also addressed under Corrective Action in clause 4.14 but it is assumed that in this case the standard is concerned with external reports of nonconformities. 

Pure piperitone was subjected to the action of purified hydrogen, in the presence of a nickel catalyst, for six hours, the temperature ranging between 175° to 180° C. The double bond in piperitone was readily opened out with the formation of menthone, but further action of the hydrogen under these conditions did not reduce the carbonyl group, even after continued treatment for two days. Under correct conditions, however, the reduction to menthol should take place. The ease with which menthone is formed in this way is of special interest, not only in connection with the production of this ketone, but also as a stage in the manufacture of menthol. 

The potential durability of a coating system can be realized only if it is applied to a suitably prepared surface, in the correct manner under correct conditions. Painting differs from any other industrial processes in that it is not susceptible to operator abuse or adverse environmental influences throughout all stages of the work. 

In patients with sinus bradycardia due to underlying correctable disorders (such as electrolyte abnormalities or hypothyroidism), management consists of correcting those disorders. 

Completeness—A measure of the amount of valid data obtained from a measurement system compared to the amount that was expected to be obtained under correct, normal conditions. 

Note that Part 820 requires that results of acceptance activities be recorded but not necessarily all raw data. Results must have audit trails. Be sensitive to the need for raw data during failure investigations under Corrective and Preventive Actions. Refer to Part 820 preamble, pp. 52,631 and 52,646. 

Overall accountability must documented and reviewed. A reconciliation of the initial inventory and the final returns must be undertaken and all discrepancies must be explained. Final disposition and destruction must be carefully documented to also allow assessment of possible detrimental environmental impact. All unused and returned medications/devices, empty containers, devices, equipment and so on, which are returned to the investigator by the study subjects, must be stored securely and under correct environmental conditions at the study site until retrieved by the monitor. The monitor will check the supplies returned and verify that they reconcile with the written specifications. All discrepancies and the reasons for any nonreturns must be documented and explained. 

Note-. Physical attributes are a strong function of the natural morphology and can be manipulated to some extent, as indicated below under corrective actions... 

Under correctly chosen conditions (mainly an appropriate emulsifier), the radiation-chemical yield of emulsion polymerization attains very high values. For instance, if sodium lauryl sulphate is used for the radiation-induced emulsion polymerization of methyl methacrylate, we have Gp = 105, and for that of butyl acrylate, Gp = 106 molecules/100 eV. 

Fig. 8.4 2° antibody controls. Controls will show that the 2° antibody binds only to the 1° antibody, (a) With several antigens present, the expected binding of the 1 ° antibody is to its antigen (No. 3) and then the fluorescent 2° antibody binds to the 1° antibody, (b) The elimination of the 1 ° antibody does not allow binding of the 2° antibody under correct conditions... 

The preparation should be carried out as quickly as possible the temperature must be kept around 0° by the addition of chopped ice, especially before the free acid is liberated from the sodium salt. Failure to observe this precaution leads to very uncertain results, whereas under correct conditions the yield of perbenzoic acid is invariably as high as 82-86 per cent of the theoretical amount. 

The macro-state OFF has a munber of possible sub-states that specify the condition of the component while not working (e.g., under corrective maintenance, under preventive maintenance, waiting for the availability of the repair team, imder test, etc). A repair rate / , is associated to the generic component /, whose macro-state is OFF -, the value is assumed to be dependent directly on the type of the maintenance action, on the values of the IFs and on the degradation state of the component. 

In specified cases they may be made by reaction of phosphine with an alkali metal (Equation 8.3), an oxide (Equation 8.4) or a metal chloride (Equation 8.5). Alternatively, the reduction, under correct conditions, of a phosphate with carbon (Equation 8.6) or hydrogen (Equation 8.7) may be used. 

Unless this part is moulded under correct conditions, carefully... 

Yes it can be estimated from theory if the right data are available but the results are subject to simplifying assumptions, which do not hold in practice. Experimental, direct determinations are always more reliable if carried out under correct conditions. 

Intramolecular reactions with both alkenes and alkynes can also be achieved under correctly chosen conditions, especially when the aldehyde contains a second donor atom that can chelate the rhodium, as in the (3-thioaldehyde 3.70 (Scheme 3.33). " Ruthenium catalysts have been used with dienes (Scheme 3.34). ... 

Destruction efficiency Potentially good, but must be verified by experiment. Complete mineralization if large quantities of chemical oxidant are used under correct conditions. 

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