Tubes in Ion Mobility Spectrometry

Pilzecker, R Bamnbach, J.I. Kurte, R., Detection of decomposition products in SF a comparison of colorimetric detector tubes and ion mobility spectrometry. Proceedings of the Conference on Electrical Insulation and Dielectric Phenomena, 2002, 865-868 DOI 10.1109/CEIDP.2002.1048932. [Pg.344]

Eiceman, G.A. Nazarov, E.G. Rodriguez, J.E. Stone, J.A. Analysis of a drift tube at ambient pressure Models and precise measurements in ion mobility spectrometry. Rev. ScL Instrum. 2001, 72, 3610-3621. [Pg.413]

DGE a AC AMS APCI API AP-MALDI APPI ASAP BIRD c CAD CE CF CF-FAB Cl CID cw CZE Da DAPCI DART DC DE DESI DIOS DTIMS EC ECD El ELDI EM ESI ETD eV f FAB FAIMS FD FI FT FTICR two-dimensional gel electrophoresis atto, 10 18 alternating current accelerator mass spectrometry atmospheric pressure chemical ionization atmospheric pressure ionization atmospheric pressure matrix-assisted laser desorption/ionization atmospheric pressure photoionization atmospheric-pressure solids analysis probe blackbody infrared radiative dissociation centi, 10-2 collision-activated dissociation capillary electrophoresis continuous flow continuous flow fast atom bombardment chemical ionization collision-induced dissociation continuous wave capillary zone electrophoresis dalton desorption atmospheric pressure chemical ionization direct analysis in real time direct current delayed extraction desorption electrospray ionization desorption/ionization on silicon drift tube ion mobility spectrometry electrochromatography electron capture dissociation electron ionization electrospray-assisted laser desorption/ionization electron multiplier electrospray ionization electron transfer dissociation electron volt femto, 1CT15 fast atom bombardment field asymmetric waveform ion mobility spectrometry field desorption field ionization Fourier transform Fourier transform ion cyclotron resonance... [Pg.11]

Ion mobility spectrometry (IMS) [3,12] is the most widely used instrument for drug detection. The sample is heated to vaporize the analyte, which is then ionized by atmospheric (ambient) pressure chemical ionization (APCI) [3]. The resulting gas-phase ions travel through a drift tube and are separated by their distinct velocities (mobilities) in a weak electrostatic field. IMS instruments use ambient air or nitrogen as the carrier gas, making it particularly adaptable to field applications. [Pg.793]

An important tool in the study of protein conformation and noncovalent protein complexes is the on-line combination of ion-mobility spectrometry (IMS) and MS. The IMS-MS instruments consists of an ESI source with related ion optics, a drift tube, and a mass spectrometer [75-76]. Quadrapole and TOF-MS instruments have been applied most frequently. In an IMS instrument, ions drift through a buffer gas under the iirfluence of a weak uniform electric field. The IMS separation of ions is based on differential mobility of ions related to shape and charge state. Within a particular charge state, compact ions show a higher mobility than more extended structures, because they experience fewer collisions. In this way, conformation differences between ions can be discovered. Compact ions have a smaller collision cross section. [Pg.456]

V/cm triangles, 275 V/cm stars, 325 V/cm and diamonds, 375 V/cm and (b) when was normalized to corresponding drift fields E. (From Tadjimukhamedov et al., A study of the performance of an ion shutter for drift tubes in atmospheric pressure ion mobility spectrometry computer models and experimental findings. Rev. Sci. Inst. 2009. With permission.)... [Pg.100]

FIGURE 8.7 Measuring resolving power in IMS. (a) The mass-selected ion mobility spectrum of methamphetamine obtained with an atmospheric drift tube IMS interfaced to a quad-rupole mass spectrometer. (b) Expanded scale of spectrum A. (From Wu et al., Electrospray ionization high-resolution ion mobility spectrometry-mass spectrometry, Anal. Chem. 1998, 70(23), 4929 938. With permission.)... [Pg.172]

As described in previous chapters, there are many different types of ion mobility methods. These include drift tube ion mobility spectrometry (DTIMS), traveling wave ion mobility spectrometry (TW-IMS), differential mobility spectrometry (DMS), differential mobility analysis (DMA), and aspiration ion mobility spectrometry (alMS). All of these IMS methods have been interfaced to MSs. [Pg.190]

Thongh IMS and ion mobility spectrometry/mass spectrometry (IMS/MS) methods may not be recognized widely for determining values for enthalpy, entropy, and kinetic constants, significant experience in the study of reactions at ambient or elevated pressures exists. In the discnssion below, examples are drawn from gas-phase reactions for associations and displacements of ions using either combined mobility-mass spectrometry or, in some instances when the chemistry was well known, a drift tube alone. The order of presentation follows that used in the prior section. In a later discussion, reactions with electrons are described. [Pg.394]