Elevated Pressure

Aerosol adniinistration of isoproterenol produces a prompt (2—5 minutes) intense bronchodilatation of relatively short (1 h) duration. The lack of P2-selectivity leads, in many cases, to tachycardia and blood pressure elevation. Also, use of isoproterenol, like all other known P-agonists, results in a down-regulation, or desensitization, of P-adrenergic receptors. This desensitization is only partial, and after time (depending on dose, patient, and agent), a stable, less responsive state is achieved in which P-agonists remain effective. Isoproterenol has been widely used for many years. 

The strong shock regime is the classic archetype and is characterized by a single narrow shock front that carries the material from its initial condition into a new high pressure, elevated temperature, high kinetic energy state. Following a quiescent period at peak pressure, whose duration depends upon... 

HilUs AE, Ulatowski JA, Barker PB, Torbey M, Ziai W, Beauchamp NJ, Oh S, Wityk RJ. A pilot randomized trial of induced blood pressure elevation effects on function and focal perfusion in acute and subacute stroke. Cerebrovasc Dis 2003 16 236-246. 

PFE is based on the adjustment of known extraction conditions of traditional solvent extraction to higher temperatures and pressures. The main reasons for enhanced extraction performance at elevated temperature and pressure are (i) solubility and mass transfer effects and (ii) disruption of surface equilibria [487]. In PFE, a certain minimum pressure is required to maintain the extraction solvent in the liquid state at a temperature above the atmospheric boiling point. High pressure elevates the boiling point of the solvent and also enhances penetration of the solvent into the sample matrix. This accelerates the desorption of analytes from the sample surface and their dissolution into the solvent. The final result is improved extraction efficiency along with short extraction time and low solvent requirements. While pressures well above the values required to keep the extraction solvent from boiling should be used, no influence on the ASE extraction efficiency is noticeable by variations from 100 to 300 bar [122]. 

Pincomb, G., Lovallo, W., McKey, B., Sung, B., Passey, R., Everson, S. and Wilson, M., Acute blood pressure elevations with caffeine in men with borderline systemic hypertension. Am J Cardiol 77(4), 270-274, 1996. 

The relationship of PbB level to systolic and diastolic blood pressure was determined in a study of 89 Boston policemen (race not specified) (Weiss et al. 1986, 1988). These policemen were under observation for health outcomes related to environmental work exposures (i.e., they had traffic exposure histories). After statistically adjusting for previous systolic blood pressure, body mass index, age, and cigarette smoking, high PbB level ( 30 pg/dL) was a significant (p=0.01) predictor of subsequent elevation in systolic blood pressure of 1.5-11 mm Hg in the working policemen with normal blood pressure. Low PbB level (20-29 pg/dL) was not a predictor of subsequent systolic blood pressure elevations. Diastolic pressure was unrelated to PbB levels. 

In the extruder the flour and water will be subjected to intense agitation and will be heated to above 100°C under pressure. Extruders are constructed to work at elevated pressures, indeed the barrel of the extruder is constructed in the same way as a gun barrel. Under these conditions the starch will gelatinise but the water cannot boil because the high pressure elevates the boiling point. 

It is estimated that approximately 90% of the patients with blood pressure elevation are affected by essential hypertension, which is by definition, hypertension of unknown etiology. Although the mechanisms responsible for essential hypertension remain obscure, extensive hemodynamic studies have now revealed the precise derangements of the systemic hemodynamics of these patients(8). 

Elevated blood pressure Elevated blood pressure and hypertension may occur within a few months of beginning use. The prevalence increases with the duration of use and age. Incidence of hypertension may directly correlate with increasing dosages of progestin. Discontinue use if elevated blood pressure occurs. Encourage women with a history of hypertension or hypertension-related diseases during pregnancy, or renal disease to use another method of contraception. 

Pheochromocytoma It is hazardous to use propranolol or atenolol unless -adrenergic blocking drugs are already in use, because this would predispose to serious blood pressure elevation. 

Biliary tract pressure elevation Biliary tract pressure elevation generally occurs for varying periods following narcotic use. However, some evidence suggests pentazocine causes little or no elevation in biliary tract pressures. 

Tolmetin (Tolectin) is indicated for the relief of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and moderate pain. It is ineffective in gouty arthritis for unknown reasons. Tolmetin can inhibit both COX-1 and COX-2 but has a moderate selectivity for COX-1. The most frequently reported side effects are GI disturbance and CNS reactions (e.g., headache, asthenia, and dizziness). These effects are less frequently observed than after aspirin or indomethacin use. Blood pressure elevation, edema, and weight gain or loss have been associated with tolmetin administration. Tolmetin metabolites in urine have been found to produce pseudoproteinuria in some laboratory tests. 

L A. By blocking renal prostaglandin synthesis, COX-2 inhibitors, such as rofecoxib, decrease the blood flow to the juxtaglomerular apparatus, thus stimulating the release of renin and subsequent Na" retention and blood pressure elevation. Rofecoxib is neither metabolized nor induced by CYP2C9. It decreases rather than increases renal blood flow and does not increase the excretion of hydrochlorothiazide. Item D is incorrect because rofecoxib has very little effect on COX-1 and prostaglandins are not a major controlling factor of peripheral vascular tone. Rofecoxib does not decrease basal metabolic rate. 

A lack of blood pressure elevation, in contrast to venlafaxine... 

Dependence is a term that is not frequently used outside of psychopharmacology but in fact is a key feature of many antihypertensive medications, hormones, and other treatments throughout medicine. Thus, several antihypertensives can produce rebound hypertension, worse than the original blood pressure elevation, when sud-... 

Opatowsky I, Feldman RM, Gross R, Feldman ST. Intraocular pressure elevation associated with inhalation and nasal corticosteroids. Ophthalmology 1995 102(2) 177-9. 

As discussed prior, diuretics were often utilized by many of the competing athletes polled during AAS use as a means of controlling blood pressure elevation. Taraxacum was probably the safest product used for this purpose. Fortunately, it is a commonly found ingredient in many OTC weight loss supplements. 

Figure 1. Attenuation of cosmogenic production rates with atmospheric pressure (elevation) and depth in rock. A) Log-linear plot of depth as a function of normalized production rate as per equation (5), assuming a rock density of 2.7 g cm-3. Slope is rock attenuation coefficient, A. B) Log-linear plot of atmospheric depth as a function of normalized production rate as per equation (3) (solid line) and as per the scaling function presented in Stone (2000) for 40° latitude (dashed line). The offset between the two lines indicates the importance of the elevation scaling relationships when reconstructing high paleoaltitudes.

The adjective originally was intended to convey the now abandoned idea that blood pressure elevation was essential for adequate perfusion of diseased tissues. 

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