Trifluoromethane mixture

Chlorodifluoro- Pentafluoroethane Azeotropic Mixture Chlorotrifluoro- Trifluoromethane Azeotrope Azeotrope... 

To [Co(en)2((S)-GluOBzl)]I2 (5.0 g, 7.3 X 10 3 mol) in dry trimethyl-phosphate (18 ml, 4A sieves) contained in a conical flask equipped with a drying tube was added methyl trifluoromethane sulfonate (8.0 g, 4.9 x 10 2 mol) and the mixture was stirred at room temperature for 30 min (Caution The alkylating agent is believed to be extremely toxic. Use a hood and avoid skin and vapor contact). The deep orange solution was then slowly poured into rapidly stirred dry ether (600 ml) and the precipitated semisolid recovered by decantation. The residue was dissolved in the minimum volume of dry methanol (10-20 ml), the product reprecipitated using further dry ether (400 ml), and the solid recovered as before. A further precipitation using methanol (10-20 ml) and dry ether (800 ml) produced the complex as a finely divided solid. This was recovered by filtration (porosity 4 sin-... 

Irradiation of hexafluorobiacetyl in the vapor phase produces a 2 1 mole ratio of carbon monoxide and hexafluoroethane, products consistent with an initial carbon-carbon bond cleavage.62 However, vapor phase irradiation of hexafluorobiacetyl in the presence of a large excess of 2,3-dimethylbutane vapor or in 2,3-dimethylbutane solution gave less than 1% carbon monoxide and trifluoromethane. No trifluoroacetaldehyde or hexafluoroacetone was produced in the latter reaction. Instead a complex mixture of products, which was not separated and identified but whose infrared showed the presence of a hydroxyl band and a diminished carbonyl band, was obtained. This observation is consistent with product formation via hydrogen abstraction. 

The reaction was carried out in a distillation column reactor with a fluidized bed of 0.5 % Ni and fluorinated A1203 at 450 C. Br2, HF, CH4 and recycled halohydrocarbons (9.8 3.3 1.2 1) were added, the mixture was cooled by a second distillation apparatus and was then recycled through to the first reactor. This gave bromotrifluoromethane (6) yield (97%) and trifluoromethane (3%). 

An optimum yield (76%) of oxoassoanine (203), contaminated with the regioisomer (228 7%) was realised, presumably via the intermediate 229, when a mixture of 227 (1 eq.) and 4-(N,N-dimethylamino)pyridine (3 eq.) was treated with trifluoromethane sulfonic anhydride (5 eq.). Similarly the methylenedioxy analogue of 224 and 225 led to anhydrolycorinone (201) which, on oxidation, provided hippadine (202). 

Material. Polymer I was made by copolymerizing a mixture of octamethylcyclotetrasiloxane, (Me2SiO)i, and 2,4,6,-trimethyl-2,4, 6-tris(3,3,3-trifluoropropyl)cyclotrisiloxane, (MeCF3CH2CH2SiO)3, in the presence of tetramethyldivinyldisiloxane, ViMe2SiOSiMe2Vi, using trifluoromethane sulfonic acid, CF3SO3H, as a catalyst. 

The dehydration of lanthanide perchlorates to obtain the anhydrous salt has been studied [13-15]. Lighter lanthanide perchlorate lose the water of hydration readily at 200°C under vacuum while the heavier lanthanide salts produced insoluble basic salts. Anhydrous heavier lanthanide perchlorates have been obtained by extraction with anhydrous acetonitrile. Utmost precaution should be exercised in the purification of lanthanide perchlorate, since the mixture of lanthanide perchlorate and acetonitrile can lead to an explosion. An alternate approach involves the addition of triethylorthoformate to the mixture or refluxing the solvent through a Soxhlet extractor packed with molecular sieves [3], In view of the hazardous nature of perchlorates, alternate materials such as lanthanide trifluoromethane sulfonates have received some attention. Lanthanide triflates are thermally stable, soluble in organic solvents, unreactive to moisture and are weak coordinating agents. Triflic acid is stronger than perchloric acid [17]. Lanthanide perchlorates and triflate have the same reduction potentials in aprotic solvents and the dissociation of the triflates is less than the perchlorates in acetonitrile [17],... 

The product from Step 5 (25 mol) was dissolved in CH2CI2 (90 kg), cooled to -30 to -20 °C, and borane-methyl sulfide (27.5 mol) and trimethylsilyl trifluoromethane-sulfonate (32.5 mol) added. After 1 hour, 10% aqueous NaHC03 (40 kg) was added, the mixture warmed to ambient temperature, stirred for 12 hours, and the isomers isolated in 90% yield. 

Hexyl trifluoroacetate reacts w ith trimethyl(trifluoromethyl)silane in the presence of a molar equivalent of tetrabutylammonium fluoride to give the silylated hemiketal 29 in. 3.5% yield. Much of the trimethyl(trifluoromcthyl)silanc is converted into the undesired trifluoromethane due to rapid quenching of the incipient trifluoromethide species by the protic impurities in the reaction mixture. "... 

SYNS CHLOROTRIFLUOROMETHANE mixed with TRIFLUOROMETHANE CHLOROTRIFLUOROMETHANE and TRIFLUOROMETHANE AZEOTROPIC MIXTURE pOT) METHANE, CHLOROTRIFLUORO-, mixt. wich TRIFLUOROMETHANE (9CI) METHANE, TRIFLUORO-, mixL with CHLOROTRIFLUOROMETHANE... 

CHLORO-l,l,2-TRIFLUOROETHYLENE see CLQ750 CHLOROTRIFLUOROMETHANE see CLR250 CHLOROTRIFLUOROMETHANE mixed with TRIFLUOROMETHANE see F00562 CHLOROTRIFLUOROMETHANE and TRIFLUOROMETHANE AZEOTROPIC MIXTURE pOT) see F00562... 

In the reaction of perfluoro(2-methylpent-2-ene) and perfluoi omethacrylamide with the bromo-trifluoromethane/tris(diethylamino)phosphane system, the products of substitution of two fluorine atoms are formed together with the monosubstituted products. The reaction with periluoro-(2-methylpropenc) gives a mixture of isomeric perfluorodienes.179... 

Evidence of weak Fl-bonds was also seen by FT microwave spectroscopy when a mixture of thiirane and trifluoromethane was expanded in a supersonic jet <2005CPL4>. The spectra could be analyzed in terms of Fl-bonding by the acidic CFl bond of trifluoromethane to sulfur and H-bonding of the two CH groups of thiirane to two fluorines, as in 110. 

A very interesting nitrating mixture has been reported by Coon, Blucher and Hill [16]. It was composed of nitric acid and trifluoromethane sulphonic acid ... 

Emission from the twisted intramolecular charge transfer (TICT) state of two fluorescent probes, 40 and 42, was studied by Sun and coworkers129 130 in supercritical ethane, trifluoromethane, SCCD and mixtures of the latter two. The bathochromic shifts increased as the density and content of CHF3 in the mixtures increased, pointing to the stabilization of the TICT state by the more polar component. Although non-polar and of small polarizability, SCCD caused larger shifts than the equally non-polar ethane, possibly due to the quadrupole moment of C02. 

These reactions proceed with 85% and 50% yield, respectively [1624], COF has been generated by irradiating mixtures of CHFg and Oj with COj laser pulses (y = 1085.8 cm ), under conditions suitable for the multiphoton dissociation of the trifluoromethane [1501a]. COF 3 is also the primary product from the multiphoton decomposition of mixtures of C3Fg and O3 [1578a]. 

In the above process, usually 2 mol of isobutylene react with each mole of cresol in the presence of acidic catalyst. Dilute H2SO4 is the most popular catalyst for both alkylation and dealkylation process. Some of the plants use p-toluene sulfonic acid or even a mixture of sulfuric acid and p-toluene sulfonic acid. It is reliably learnt that at least one plant has been using some quantities of a very strong Friedel Crafts alkylation catalyst—Triflic acid or trifluoromethane... 

F-2-fluoro-2-deoxyglucose (2-FDG) is normally produced in places where a cyclotron is locally available. Its molecular formula is CsHn FOs with molecular weight of 181.3 daltons. 18F-2-FDG can be produced by electrophilic substitution with 18F-fluorine gas or nucleophilic displacement with 18F-fluoride ions. The radiochemical yield is low with the electrophilic substitution, so the nucleophilic displacement reaction has become the method of choice for 18F-FDG synthesis. Deoxyglucose is labeled with 18F by nucleophilic displacement reaction of an acetylated sugar derivative followed by hydrolysis (Hamacher et al, 1986). In nucleophilic substitution, a fluoride ion reacts to fluorinate the sugar derivative. A solution of 1,3,4,6-tetra-O-acetyl-2-0-trifluoromethane-sulfonyl-/ -D-mannopyranose in anhydrous acetonitrile is added to a dry residue of 18F-fluoride containing aminopolyether (Kryptofix 2.2.2) and potassium carbonate (Fig. 8.1). Kryptofix 2.2.2 is used as a catalyst to enhance the reactivity of the fluoride ions. The mixture is heated... 

Hexafluorobiacetyl. In the gas phase, hexafluorobiacetyl behaved 169> in the same manner as biacetyl, affording carbon monoxide and hexa-fluoroethane in stoichiometric ratio. However, in the presence of hydrocarbon vapor or in hydrocarbon solution, the disappearance of dione was not accompanied by formation of cleavage products. For example, photolysis (A >3000 A, 65°) of hexafluorobiacetyl in 150 molar excess of 2,3-dimethylbutane until 84% of starting material had disappeared resulted in only 0.5% of carbon monoxide, an equivalent amount of trifluoromethane, and a complex mixture of other products. On the basis of carbonyl and hydroxyl absorption in the infrared, it was assumed that the excited dione abstracted hydrogen from hydrocarbons to give products of photoreduction, photoaddition, etc. Occurrence of H-abstraction in the gas phase is unique. 

Since naphthalene-SCF mixtures have been so widely studied, it is instructive to consider the solubility behavior of just one of these systems, the naphthalene-C02 system, to highlight the solvent properties of a supercritical fluid solvent. In chapter 1 the effects of pressure and temperature on the solubility of naphthalene in ethylene were described. The solubility behavior is quite similar in carbon dioxide, in trifluoromethane, or even in xenon, although each system achieves its own absolute solubility level of naphthalene. 

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