Triethyllead chloride

Estes el al. [722] described a method for the measurement of triethyl- and trimethyllead chloride in potable water, using fused silica capillary column gas chromatography with microwave excited helium plasma lead specific detection. Element specific detection verified the elution of lead species, a definite advantage to the packed column method. The method involved the initial extraction of trialkyllead ions from water into benzene, which was then vacuum reduced to further concentrate the compounds. Direct injection of the vacuum concentrated solutions into the gas chromatography-microwave excited helium plasma system gave delectability of triethyllead chloride at the 30mg L 1 level... 

The redistribution reaction in lead compounds is straightforward and there are no appreciable side reactions. It is normally carried out commercially in the liquid phase at substantially room temperature. However, a catalyst is required to effect the reaction with lead compounds. A number of catalysts have been patented, but the exact procedure as practiced commercially has never been revealed. Among the effective catalysts are activated alumina and other activated metal oxides, triethyllead chloride, triethyllead iodide, phosphorus trichloride, arsenic trichloride, bismuth trichloride, iron(III)chloride, zirconium(IV)-chloride, tin(IV)chloride, zinc chloride, zinc fluoride, mercury(II)chloride, boron trifluoride, aluminum chloride, aluminum bromide, dimethyl-aluminum chloride, and platinum(IV)chloride 43,70-72,79,80,97,117, 131,31s) A separate catalyst compound is not required for the exchange between R.jPb and R3PbX compounds however, this type of uncatalyzed exchange is rather slow. Again, the products are practically a random mixture. 

Lead speciation (inorganic lead, trimethyllead chloride, triethyllead chloride, and triphenyllead chloride) has been performed by Al-Rashdan et al. [26]. Despite previous use of a gradient elution (10% to 70% methanol in water) with inductively coupled plasma atomic emission spectrometry (ICP-AES) detection, an isocratic elution was used with ICP-MS detection because gradient elution causes plasma instability. A 30% methanol/water mobile phase was used, along with a CI8 column, and the pH was optimized by using acetate buffer. 

The reactions of hexaorganodileads with nitric acid 358,359), dimethyl-acetic acid 358), magnesium/magnesium iodide 296), aluminum chloride 349, 360), and alkyl halides 280,361, 362) also result in Pb—Pb cleavage. Reaction of hexaethyldilead with sulfuryl chloride, thionyl chloride, sulfur dichloride, and sulfur monochloride has been reported (363). The yield of triethyllead chloride was observed to decrease with increasing nucleophilic character of the sulfur atom, in the order listed above. 

Ammitzb0ll, T. Chick embryo brain cultures and triethyllead chloride. Ph.D. thesis, Univ. Odense, Denmark (1977). 

Grundt, L, H. Offner, G. Konat, and J. Clausen The effect of methylmercury chloride and triethyllead chloride on sulphate incorporation into sulphatides of rat cerebellum shces during myelination. Environ. Physiol. Biochem. 4, 166 (1974). 

The first organolead-substituted amine, triethyl(5 c-butylamino)lead was patented in 1959 as a herbicide 107). It was prepared from triethyllead chloride and sodium r c-butylamide in refluxing benzene. On exposure to air it slowly hydrolyzes. The other two known substituted amines in addition to lead contain silicon and germanium, respectively. Trimethylplumbyl-bis(trimethylsilyl)amine 36) has been prepared by the reaction... 

Two substituted imides, viz. iV-triethylplumbylphthalimide and -tetra-chlorophthalimide, and one substituted hydrazide, viz. iV-triethylplumbyl-phthalohydrazide, have been described in the patent literature as fungicides 114, 115). The imides were prepared from triethyllead hydroxide and phthalimide, or tetrachlorophthalimide in ethanol. iV-triethylplumbyl-phthalohydrazide (or iV-triethyllead-2,3-dihydro-l,4-phthalazinedione as it is called in the patent) was obtained from the reaction between sodium hydroxide, phthalohydrazide, and triethyllead chloride in water. The crude hydrazide is purified by precipitating it in ethanolic solution with water. 

---