Toxicology biochemical research

Dow Chemical Company. 1962. Results of range finding toxicological tests on isophorone. Unpublished report by the Dow Chemical Company, Biochemical Research Laboratory, Midland, Ml. OTS 8d submission Doc. ID 878210479, Microfiche No. 206147. 

Dow. 1959. Results of range finding toxicological tests on Dowanol EB (sanitized). Dow Chemical Co., Biochemical Research Eaboratory, Midland, MI. EPA/OTS No. 86-89001175S. 

The editors sincerely hope that this book will, with its introduction into the basic principles and limitations of the presently available trace analytical methodology and its detailed description of reliable procedures and quality control measures, serve as a valuable aid for all those who are involved in trace element analysis. It should be especially beneficial for analysts and researchers in clinical chemistry, toxicology, biochemical and environmental research first as a general overview and second to serve as a collection of elaborated methods for the reliable determination of the above-mentioned elements and some of their species in selected (human) biological specimens. 

Toxicology LD50 (IP, mouse) 154 mg/kg, (intramuscular, mouse) 108 mg/kg poison by IP and intramuscular routes TSCA listed Hazardous Decomp. Prods. Heated to decomp., emits toxic fumes of SOx Uses Reducing agent for proteins and enzymes, biochemical research drug Manuf./Distrib. AMRESCO http //www.amresco-inc.com, Adept Sol ns. Aldrich http //www.sigma-aldrich.com, Am. Int l. http //www.aicma.com, Bio-Rad Labs http //WWW. bio-rad. com Biosynth AG http //www.biosynth.com, Inalco Pharmaceuticals Indofine http //www.indofinechemicai.com, J.T. Baker http //www.jtbaker.com, Roche Molecular Biochems. 

Synonyms 2,3-Dihydroxypropanal Glyceric aldehyde Glycerose Empirical CsHeOs Formula HOCH2CH2OCHO Properties Tasteless cryst. insol. in benzene, petroleum ether, pentane m.w. 90.09 m.p. 145 C Toxicology LDLo (oral, rat) 5 g/kg Uses Biochemical research intermediate nutrition preparation of polyesters adhesives cellulose modifier leather tanning... 

Properties Colorless rhombic crystals odorless freely sol. in ammonium hydroxide, dilute acids sparingly sol. in alcohol, ether insol. in water m.w. 151.15 m.p. 300 C min. dec. > 360 C Toxicology TDLo (subcut., rat, 26 wks, intermittent) 1300 mg/kg questionable carcinogen suspected tumorigen human mutagenic data TSCA listed Hazardous Decomp. Prods. Heated to decomp., emits toxic fumes of NOx Uses Biochemical research colorant for cosmetics (lipsticks, nail polishes, eye makeup), external pharmaceuticals, eye use ... 

C) m.p. 295 C subl. 145-148 C Toxicology LD50 (IP, rat) 5379 mg/kg LDLo (subcut., rabbit) 2620 mg/kg mod. toxic by subcut. route experimental teratogen, reproductive effects TSCA listed Hazardous Decomp. Prods. Heated to decomp., emits toxic fumes of NOx Uses Antistat in cosmetics nutrient, dietary supplement, flavor modifier in foods biochemical research infusion sol ns. diagnostic aids raw material in peptide drugs flavor in pharmaceuticals food flavoring (Japan)... 

Toxicology No known toxicity Uses Emollient, conditioner, humectant in cosmetics moisturizer, conditioner for hair and skin care prods. biochemical research vitamin, nutrient, dietary suppiement in foods and pharmaceuticals digestive aid antiinflammatory stimulator of cell proliferation promotes heaiing... 

This leading textbook in the field examines the mechanisms underlying toxicity, particularly the events at the molecular level and the factors that determine and affect toxicity. The new edition is updated to reflect the latest research in the biochemical basis of toxicology and the growing concerns over the adverse effects of drugs, environmental pollution, and occupational hazards. 

J.A. Bond, Department of Biochemical Toxicology, Chemical Industry Institute of Toxicology, PO Box 12137, 6 Davis Drive, Research Triangle Park, NC 27709, United States... 

Bolgova, O.M. (1993). On the relation between the level of eicosotrienoic acids with the ecologo-physiological condition of the fish (In Russian). In Biochemical Methods in Ecological and Toxicological Research (O.I. Potapova and Y.A. Smirnov, eds), pp. 170-174. Petrozavodsk. 

Sidorov, V.S.,Vysotskaya, R.U. and Nemova, N.N. (1993). Evolutionary aspects of ecologo-biochemical monitoring (In Russian). In Biochemical Methods in Ecology and Toxicological Researches (V. Sidorov, ed.), pp. 5-35, Karelian Scientific Centre Publishing, Petrozavodsk. 

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