Toxic Substances Control Act Inventory

CHEMLIST is aregulated chemicals listing. Regulated substances listed on the Environmental Protection Agency Toxic Substances Control Act Inventory, the European Inventory of Existing Commercial Chemical Substances, and the Domestic and Nondomestic Substances List from Canada are well covered, as well as other lists of hazardous substances. More than 249,000 substances are listed. 

Listed in the Environmental Protection Agency Toxic Substances Control Act Inventory (EPA s TSCA Inventory) or in the National Institutes for Occupational Safety and Health Registry of Toxic Effects of Chemical Substances (NIOSH s RTECS), and... 

A similar situation exists for the hazard assessment of environmental pollutants. More than 15 million distinct chemical entities have been registered with the Chemical Abstract Service and the list is growing by nearly 775,000 per year. About 1000 of these chemicals enter into societal use every year. Few of these chemicals have experimental properties needed for risk assessment. Table 1 gives a partial list of properties necessary for a reasonable risk assessment of a chemical. In the United States, the Toxic Substances Control Act Inventory has about 74,000 entries and the list is growing by nearly 3000 per year. Of the approximately 3000 chemicals... 

EPA. 1992a. Toxic Substances Control Act Inventory 1990 [Chemical Update System Database]. Washington, DC U.S. Environmental Protection Agency, Office of Pollution Prevention and Toxics, Information Management Division. 

The Environmental Protection Agency (EPA) explained the conventions applied to listings of polymeric chemical substances for purposes of Premanufacture Notification (PMN) reporting and the TSCA Inventory. The principal guidance document in which the conventions are explained is titled Toxic Substances Control Act Inventory Representation for Polymeric Substances, which was published on 29 March 1995. This discussion of polymer nomenclature conventions under TSCA begins with general guidelines, followed by a discussion of how polymers are identified... 

C.F.R. 710.4(c)(2) see also Toxic Substances Control Act Inventory Representation For Products Containing Two Or More Substances Formulated And Statutory Mixtures (undated) [hereinafter Formulated and Statutory Mixtures] available at http //regulations. gov in docket number EPA-HQ-OPPT-2007-0392. 

U.S. EPA, Toxic Substances Control Act Inventory Representation for Polymeric Substances, 1 (Mar. 29,1995). 

The EPA explained its preferred methods for representing polymers on the Inventory in its 1995 Toxic Substances Control Act Inventory Representation for Polymeric Substances, and began by defining what substances can be hsted on the Inventory as polymers.For this purpose, EPA defined polymers as sequences of one or more types of monomer units, where a monomer unit is the reacted form of a monomer bonded to two or more other molecules. A polymer must also have a distribution of molecules of different molecular weights attributable primarily to different numbers of monomer units in the molecules. If all the molecules of a specific substance always have the same chain length then that substance is described on the Inventory as a specific substance with a defined structure and molecular weight, and not as a polymer. There are limited exceptions to this rule. Some chemicals that chemists may consider to be polymers do not fall within this definition because they do not have a distribution of molecular weights. 

Most polymers are listed by their monomers and other starting materials, which the EPA calls monomer-based representation. The EPA succinctly summarized this method in the Toxic Substances Control Act Inventory Representation for Polymeric Substances in section II A ... 

UVCB substances are substances of unknown or variable composition, complex reaction products, and biological materials that cannot be represented by unique structures and molecular formulas. Some UVCB substances are not adequately described by their CA Names and have supplemental definitions that are considered integral parts of the names for TSCA purposes. The guidance, entitled Toxic Substances Control Act Inventory Representation For Chemical Substances Of Unknown Or Variable Composition, Complex Reaction Products And Biological Materials UVCB Substances points out that any substance that matches a CA Name but is not covered by the substance description is not considered to be covered by that Inventory listing. 

The guidance on how to name complex reaction products is entitled Toxic Substances Control Act Inventory Representation for Combinations of Two or More Substances Complex Reaction Products. It applies only to chemicals made by a chemical reaction, and not to formulated mixtures, which are made simply by mixing with no chemical reaction. Its primary purpose is to explain when complex reaction products should be named as one reaction product, or as a series of individual components. 

Compare the broader definition given in the Toxic Substances Control Act Inventory Representation For Polymeric Substances, section I A. 

Fed. Reg. 64946 (Oct. 31, 2008) Toxic Substances Control Act Inventory Status of Carbon Nanotubes 73 FR 64946 Nanotubes... 

Toxic Substances Control Act Inventory Representation For Certain... 

Toxic Substances Control Act Inventory Representation For Chemical Substances Of Unknown or Variable Composition, Complex Reaction Products And Biological Materials UVCB Substances, available through http //www.epa.gov/opptintr/newchems/pubs/guideman.htm... 

Letter from Mary E. Cushmac, Chief, Policy and Administrative Section, New Chemicals Branch, to Fred H. Parry of Hoechst Celanese Corporation (Aug. 12,1994) in collection of h 7 Letters Toxic Substances Control Act Inventory Representation For Polymeric Substances Polymeric Substances... 

Company name] will be sending you a sample of [identify R D substance]. This substance is a research and development product that is [not listed on the Toxic Substances Control Act Inventory] [or] [subject to a Significant New Use Rule issued under the Toxic Substances Control Act give citation of the SNUR], You may use this product only for research and development as required by the TSCA regulations found at 40 C.F.R. 720.36 or 721.47. 

Environmental Protection Agency, 2008a. Toxic substances control act inventory of carbon nanotubes. Federal Register 73 (212), 64946-64947. 

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