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Toll synthesis

If the technical staff from the client company recognizes that a toller may be asked to perform new analyses and make operating decisions based upon the results, the client may help the toller develop the needed procedures and skills required to make these decisions. Typically a round robin laboratory qualification exercise will be performed. Samples of known standards and unknown concentrations of the materials to be analyzed for the toll will be prepared and sent to both laboratories. This can help ensure that equipment calibration is synchronized and that the toller is capable of performing accurate measurements. In some cases, the toller may be the party with the chemical, process, or synthesis specific expertise. [Pg.83]

Spock, L. (1998). Tolling Practices for Highway Facilities. Synthesis of Highway Practice 262. National Cooperative Highway Research Program (NCHRP). Transportation Research Board, National Research Council. Washington, DC National Academy Press. [Pg.1154]

Systemic Gentamicin Inhibits protein synthesis by binding to E. toll, Enterobaciev, Klebsiella, Prof e us,... [Pg.12]

M Bodanszky, JC Tolle. Side reactions in peptide synthesis. V. A reexamination of the mixed anhydride method. Ini Pept Prot Res 10, 380, 1977. [Pg.203]

Because of the high functional values that polyimides can provide, a small-scale custom synthesis by users or toll producers is often economically viable despite high cost, especially for aerospace and microelectronic applications. For the majority of industrial applications, the yellow color generally associated with polyimides is quite acceptable. However, transparency or low absorbance is an essential requirement in some applications such as multilayer thermal insulation blankets for satellites and protective coatings for solar cells and other space components (93). For interlayer dielectric applications in semiconductor devices, polyimides having low and controlled thermal expansion coefficients are required to match those of substrate materials such as metals, ceramics, and semiconductors used in those devices (94). [Pg.405]

Synthesis of Toll-Like Receptor-2 Targeting Lipopeptides as Self-Adjuvanting Vaccines... [Pg.247]

Exposure of Caco-2 cells to Se. 857 pretreated with the spent culture supernatant (SCS) of LAB strains resulted in a marked inhibition of IL-8 synthesis. Pretreatment of Se. 857 with lactobacilli SCS (pH 4.5) most likely dissociates the flagella. Since flagellin is an important stimulus for epithelial IL-8 secretion because of its ability to activate Toll-like receptor 5 (Huang et al. 2004), these partly aflagellated bacteria do not equally, effectively synthesize IL-8 as the flagellated ones. [Pg.80]

What of the death toll The most conservative estimates were 3,000 at the time, with about 200,000 injured. More recent estimates suggest that 16,000 people may have died as a result of the accident. How did it happen The factory, which was owned by the American Union Carbide company, was making Sevin, or carbaryl, an insecticide. Methyhsocyanate was one of the components of the synthesis, of which a large amount was stored in a tank. It seems that water was able to enter the tank via a newly fitted pipe because of a faulty valve. The water caused a reaction when it mixed with the methyhsocyanate, producing heat, which raised the temperature to such an extent that the liquid chemical boiled and was converted into a gas, which overwhelmed the containment system. It seems there was no trap to contain the excess, no flare system, and the scrubber system was overloaded. It was clear that the safety systems were inadequate. [Pg.173]

Nina Tolle, born in 1981 in Osnabriick, Germany, started studying chemistry at the University of Gottingen, Germany, in 2001. She joined the research group of Professor Tietze in 2005 and received her diploma in 2006. She stayed in the same group for her doctoral research which deals with Lewis-acid mediated domino-reactions for the synthesis of spiroamine structures with the objective of natural product synthesis. [Pg.292]

Jong, L., Zaveri, N., Toll, L. The design and synthesis of a novel qui-nolizidine template for potent opioid and opioid receptor-like (ORLl, NOP) receptor ligands. Bioorg. Med. Chem. Lett. 2004, 14, 181—185. [Pg.379]

Although l,25(OH)2D3 obviously acts primarily by dampening on APCs, newer results indicate an active immunoprotective and especially antimicrobial role of l,25(OH)2D3 [91]. Activation of pathogen associated molecular patterns on macrophages such as Toll-like receptor (TLR) 2 leads to VDR expression and to local synthesis of l,25(OH)2D3. This in turn induced expression of cathelicidin, an antimicrobial peptide of the skin [92], Vice versa, VDR ligation may increase TLR2 expression on keratinocytes and thereby complement expression of cathelicidin [93]. [Pg.334]

The proteoglycans in this family, which includes decorin, biglycan, lumican, and fibromodulin, are major components of the interstitial matrix produced by fibroblasts and other cells. The core proteins are small (37-45 kDa) and have several leucine-rich motifs [112] with similarity to the LH-CG receptor, thyrotropin receptor, and Drosophila proteins chaoptin and toll. Core proteins of this family characteristically undergo proteolytic processing following synthesis, with removal of an additional small peptide from the N-terminus. [Pg.17]

Walton, K.A. et al. Receptors involved in the oxidized l-pahnitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine-mediated synthesis of interleukin-8. A role for Toll-like receptor 4 and a glycosylphosphatidyhnositol-anchored protein. J. Biol Chem. 278 (2003b) 29661-6. [Pg.350]

Synthesis, opiate receptor binding, analgetic activity and conformational studies of 2-R-2(hydroxybenzyl)piperidines Loew, G. H. Lawson, J. A. Toll, L. Polgar, W. Uyeno, E. T. [Pg.123]

Losartan blocks the vascular constrictor effect of Ang II, the Ang Il-induced aldosterone synthesis and/or release, and the All-induced cardiovascular growth. In various models of experimental hypertension, losartan prevents or reverses the elevated blood pressure and the associated cardiovascular hypertrophy similar to angiotensin converting enzyme (ACE) inhibitors. Subsequently con-tolled clinical trials revealed that losartan is a new and valuable drug for treatment of hyper-... [Pg.360]

The function of hyaluronic acid was initially confined to the maintenance and sta-bihty of the ECM (96). However, the action of hyaluronic acid varies with its size, which determines its function in a cell-type specific manner (97-101). Hyaluronic acid represents more than 50% of the ECM in the skin. High molecular weight hyaluronic acid (>1,000 kDa) controls tissue water content, ECM lubrication, structural integrity, free oxygen radicals, and distribution of plasma proteins (96,100,101). The synthesis of hyaluronic acid is achieved by hyaluronan synthase-1 to -3 (102,103). The stability of hyaluronic acid varies with its microenvironment, as its half-life is less than 10 min in blood, up to 12 h in the skin, and extends to months in the vitreous gel of the eye (100,101). Hyaluronic acid is the only GAG with a function of its breakdown molecules, as small hyaluronic acid molecules and fragments stimulated the maturation of dentritic cells and the synthesis of proinflammatory IL-lp, IL-12, and TNF-a (103-105). The latter effect seems to be restricted to an interaction of hyaluronic acid fragments with the Toll-like receptor 4 (104,105). The observation that bacterial spreading in the... [Pg.214]


See other pages where Toll synthesis is mentioned: [Pg.481]    [Pg.499]    [Pg.93]    [Pg.94]    [Pg.145]    [Pg.481]    [Pg.499]    [Pg.93]    [Pg.94]    [Pg.145]    [Pg.495]    [Pg.207]    [Pg.207]    [Pg.55]    [Pg.368]    [Pg.130]    [Pg.206]    [Pg.149]    [Pg.210]    [Pg.1]    [Pg.247]    [Pg.53]    [Pg.304]    [Pg.495]    [Pg.45]    [Pg.85]    [Pg.1646]    [Pg.600]    [Pg.222]    [Pg.3073]    [Pg.358]    [Pg.17]    [Pg.290]    [Pg.937]    [Pg.442]   
See also in sourсe #XX -- [ Pg.94 ]




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