Target, targets strategies

Balakrishna, S. and Biegler, L.T., 1992b. Targeting strategies for the synthesis and energy integration of non-isothermal reactor networks. Industrial and Engineering Chemistry Research, 31(9), 2152. 

K. C. Nicolaou and E. J. Sorensen, in Classics in Total Synthesis, Targets, Strategies, and Methods, VCH, Weinheim, 1996. 

Both target and signal amplification systems have been successfully employed to detect and quantitate specific nucleic acid sequences in clinical specimens. Polymerase chain reaction (PCR), nucleic acid sequence-based amplification (NASBA), transcription-mediated amplification (TMA), strand displacement amplification (SDA), and ligase chain reaction (LCR) are all examples of enzyme-mediated, target amplification strategies that are capable of producing billions of... 

Various researchers have applied the receptor-targeted strategy in pharmacological models for tumor-targeted delivery of pDNA expressing tumor necrosis factor alpha (TNFa). For example, Tf- or Tf-PEG-shielded PEI polyplexes have been used... 

Fig. 1.3 Prediction of the most appropriate subcellular targeting strategies by agroinfiltration. The levels of an industrial enzyme (IE) are shown in agroinfiltrated and transgenic alfalfa leaves using different subcellular targeting peptides. Equal amounts of total soluble leaf proteins were separated by SDS-PAGE and blotted onto a PVDF membrane. Polyclonal anti-IE IgGs were used for detection.

Balakrishna, S. and L. T. Biegler. Targeting Strategies for the Synthesis and Energy Integration of Nonisothermal Reactor Networks. Ind Eng Chem Res 31 2152-2164 (1992). 

P. S. Huang, A. Oliff, Drug-Targeting Strategies in Cancer Therapy , Curr. Opin. Genet. Dev. 2001, 11, 104-110. 

Reed JC. Dysregulation of apoptosis in cancer. J Clin Oncol 1999 17 2941-2953. Morisaki T, Katano M. Mitochondria-targeting therapeutic strategies for overcoming chemoresistance and progression of cancer. Curr Med Chem 2003 10(23) 2517-2521. 

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