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Strategies External to the Target Structure

The last-mentioned property of a synthetic process, i.e. versatility, is frequently an important consideration in research on optimally effective therapeutic agents in which the synthesis of a large series of structural analogs from a single intermediate is desirable. This aspect of the problem-solving environment can play a decisive role in synthetic design. [Pg.76]

One important human problem-solving strategy is the application of imagination or intelligent use of a chain of hypotheses to guide the search for an effective line of retrosynthetic analysis. This inductive problem-solving dimension has been discussed previously. [Pg.77]

It is not surprising that multistep synthesis of challenging and complex target molecules is an engine for the discovery of new synthetic principles and novel methodology which may have very broad application. Just as each component of structural complexity can signal a strategy for synthesis, each obstacle to the realization of a chemical synthesis presents an opportunity for scientific discovery. [Pg.77]

Another external consideration which may strongly influence retrosynthetic analysis is connected with the available body of knowledge on chemical transformations of target structure. In [Pg.76]

The principles and strategies of retrosynthetic analysis facilitate the discovery of possible synthetic pathways to a complex target structure. Exhaustive and systematic analysis over a period of time generally reveals a surprisingly large number and diversity of such candidate routes. Such [Pg.77]


One of the most prevalent compensation strategies is to establish a target salary that is tied to compensation for similar positions in the appropriate competitive marketplace. Market pricing is a formal process for determining the external value of a position compared to an organization s competitive market. This is a job-based method of defining compensation structure. [Pg.90]


See other pages where Strategies External to the Target Structure is mentioned: [Pg.59]    [Pg.76]    [Pg.69]    [Pg.86]    [Pg.59]    [Pg.76]    [Pg.59]    [Pg.76]    [Pg.69]    [Pg.86]    [Pg.59]    [Pg.76]    [Pg.576]    [Pg.499]    [Pg.217]    [Pg.162]    [Pg.205]    [Pg.3]    [Pg.67]    [Pg.387]    [Pg.68]    [Pg.1315]    [Pg.2]    [Pg.337]    [Pg.57]    [Pg.74]    [Pg.248]    [Pg.34]   


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Structures external

Target structure

Target, targets strategies

The Strategy

The target

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