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A Typical Cellular Targeting Strategy Using 1-D NS-Based Nanostructures

A Typical Cellular Targeting Strategy Using 1-D NS-Based Nanostructures [Pg.94]

A range of synthetic peptides has been proposed for the delivery of nanostructures bearing cargo molecules through the plasma membrane barrier. These are derived from sequences expressed on viruses, such as HIV transactivator of transcription (TAT) [32-36], for which internalization via a glycosaminoglycan (GAG)-mediated [Pg.94]

an understanding is available of at least some of the mechanisms via which 1-D NS nanostructures can interact directly with cells. In the following text we will discuss the range of biomolecules that can be chemically linked to these structures. [Pg.96]

As discussed above, one reason why nanomaterials have generated so much excitement among the research and medical communities is that their small size often provides them with novel chemical and physical properties that are not found in bulk materials composed of the same substances. This may be due to a variety of factors, including the small size of nanomaterials, their composition, their surface chemistry and their ability to aggregate. The use of nanomaterials in the [Pg.96]




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1-D nanostructures

A strategy

Based Strategies

Cellular targets

Strategy use

Target based

Target, targets strategies

Use as Bases

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