Suppression test

Initial screening tests to confirm the presence of hypercorti-solism and differentiate Cushing s syndrome from conditions with similar presentations include 24-hour urinary free cortisol determination and overnight low-dose dexam-ethasone suppression test (DST) (Table 42-9). [Pg.694]

Dexamethasone suppression test (DST) 8 00 am cortisol less 0.0276 Less than 0.14 pmol/L... [Pg.1547]

Dexamethasone Suppression Test A neuroendocrine assessment of hypothalamic noradrenergic neuronal activity used in depression. [Pg.241]

The answer is d. (Hardman, p 1481.) Of the glucocorticoids listed, dexamethasone is the most potent. The dexamethasone suppression test has several uses—it allows not only complete suppression of pituitary ACTH production, but also accurate measurement of endogenous corticosteroids... [Pg.264]

The presence of hypercortisolism can be established with a midnight plasma cortisol, late-night (11 PM) salivary cortisol, 24-hour urine free cortisol, and/or low-dose dexamethasone suppression test. [Pg.217]

Other tests that can help determine the etiology include the high-dose dexamethasone suppression test, plasma ACTH test, metyrapone stimulation test, corticotropin-releasing hormone stimulation test or inferior petrosal sinus sampling. [Pg.217]

XIC of +MRM (4 pairs) 327.2/275.1 amu from Sample 11 (MCX Blank) of05 04 04Ion Suppression Tests.wiff (Turbo Spray) Max. 1.0e5 cps... [Pg.18]

Suppression tests For Cushing syndrome, give 1 mg at 11 pm. Draw blood for plasma cortisol determination the following day at 8 am. For greater accuracy, give 0.5 mg every 6 hours for 48 hours. Collect 24-hour urine to determine 17-hydroxycorticosteroid excretion. [Pg.257]

Diagnostic use (except ievothyroxine) Diagnostic use in suppression tests to differentiate suspected hyperthyroidism from euthyroidism. [Pg.340]

Monitoring Treatment of patients with thyroid hormones requires the periodic assessment of thyroid status by means of appropriate laboratory tests. The TSH suppression test can be used to test the effectiveness of any thyroid preparation. [Pg.350]

Pheochromocytoma diagnosis (overnight clonidine suppression test) 0.3 mg... [Pg.553]

Martini and Wood (2002) tested the bioavailability of 3 different sources of Ca in 12 healthy elderly subjects (9 women and 3 men of mean SEM age 70 3 and 76 6 years, respectively) in a 6-week crossover trial conducted in a Human Study Unit. Each Ca source supplied 1000 mg Ca/day and was ingested for 1 week with meals (as 500 mg Ca 2x/day), thus contributing to a high-Ca intake (1300 mg Ca/day). A low-Ca intake (300 mg Ca/day strictly from the basal diet) was adhered to for 1 week in-between each treatment. The Ca sources included skim milk, CCM-fortified OJ, and a dietary supplement of CaCOa. Assessment parameters were indirect measures predicted to reflect the relative bioavailability of Ca postprandially via an acute PTH suppression test (hourly for 4h). Longer-term responses to Ca supplementation were assessed via a number of urinary and serum hormone, mineral, and bone resorption biomarkers (i.e., vitamin D, Ca, phosphorus, and collagen t) e 1 N-telopeptide cross-links). [Pg.265]

Table 3 Summary of data from studies of using the dexamethasone suppression test...

Altemus M, Cloitre M, Dhabhar FR (2003) Enhanced cellular immune responses in women with PTSD related to childhood abuse. Am J Psychiatry 160 1705-1707 Anisman H, Griffiths J, Matheson K, Ravindran AV, Merali Z (2001) Posttraumatic stress symptoms and salivary cortisol levels. Am J Psychiatry 158 1509-1511 Atmaca M, Kuloglu M, Tezcan E, Onal S, Ustundag B (2002) Neopterin levels and dexam-ethasone suppression test in posttraumatic stress disorder. Eur Arch Psychiatry Clin Neurosci 252 161-165... [Pg.398]

Goenjian AK, Yehuda R, Pynoos RS, Steinberg AM, Tashjian M, Yang RK, Najarian LM, Fairbanks LA (1996) Basal cortisol, dexamethasone suppression of cortisol and MHPG in adolescents after the 1988 earthquake in Armenia. Am J Psychiatry 153 929-934 Gormley GJ, Lowy MT, Reder AT, Hospelhorn VD, Antel JP, Meltzer HY (1985) Glucocorticoid receptors in depression relationship to the dexamethasone suppression test. Am J Psychiatry 142 1278-1284... [Pg.399]

Grossman R, Yehuda R, New A, Schmeidler J, Silverman J, Mitropoulous V, Sta Maria N, Bgolier J, Siever L (2003) Dexamethasone suppression test findings in subjects with personality disorders associations with posttraumatic stress disorder and major depression. Am J Psychiatry 160 1291-1298... [Pg.399]

Kosten TR, Wahby V, Giller E, Mason J (1990) The dexamethasone suppression test and thyrotropin-releasing hormone stimulation test in posttraumatic stress disorder. Biol Psychiatry 28 657-664... [Pg.400]

Krishucm KRR, Rayasam K, Reed D, Smith M, ChapeU P, Saunders WB, Ritchie JC, Carroll BJ, Nemeroff CB (1993) The corticotropin releasing factor stimulation test in patients with major depression relationship to dexamethasone suppression test results. Depression 1 133-136... [Pg.400]

Newport DJ, Heim C, Bonsall R, Miller AH, Nemeroff CB (2004) Pituitary-adrenal responses to standard and low-dose dexamethasone suppression tests in adult survivors of child abuse. Biol Psychiatry 55 10-20... [Pg.401]

T3 suppression test PO 75-100 meg/day for 7 days then repeat thyroid uptake test. [Pg.701]

Weller, E.B., Weller, R.A., Fristad, M.A., and Bowes, J.M. (1990) Dexamethasone suppression test and depressive symptoms in bereaved children a preliminary report. / Neuropsychiatry Clin Neurosci 2 418-421. [Pg.123]

American Psychiatric Association (1987) The dexamethasone suppression test an overview of its current status in psychiatry. The APA Task Force on Laboratory Tests in Psychiatry. Am J Psychiatry 144 1253-1262. [Pg.133]

Carroll, B.J. (1982) The dexamethasone suppression test for melancholia. Br J Psychiatry 140 292-304. [Pg.133]

DST, dexamethasone suppression test HPA, hypothalamic—pituitary-adrenal. [Pg.585]

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