Dexamethasone suppression test high-dose

Other tests that can help determine the etiology include the high-dose dexamethasone suppression test, plasma ACTH test, metyrapone stimulation test, corticotropin-releasing hormone stimulation test or inferior petrosal sinus sampling. 

Rationale The rationale for this test is similar to the rationale for the multiple high-dose dexamethasone suppression test (see Box 51-7),... 

Fig. 3 The dexamethasone suppression test. Palicnl A showed a >75% fall in urin ary cortisol excretion on the low dose. This is a normal response. Patienl B showed stnite suppression of cortisol secretion on the high dose. This is typical of pituitary-dependent (. ushing s syndrome.

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