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Dexamethasone suppression test

Dexamethasone suppression test (DST) 8 00 am cortisol less 0.0276 Less than 0.14 pmol/L... [Pg.1547]

Dexamethasone Suppression Test A neuroendocrine assessment of hypothalamic noradrenergic neuronal activity used in depression. [Pg.241]

The answer is d. (Hardman, p 1481.) Of the glucocorticoids listed, dexamethasone is the most potent. The dexamethasone suppression test has several uses—it allows not only complete suppression of pituitary ACTH production, but also accurate measurement of endogenous corticosteroids... [Pg.264]

The presence of hypercortisolism can be established with a midnight plasma cortisol, late-night (11 PM) salivary cortisol, 24-hour urine free cortisol, and/or low-dose dexamethasone suppression test. [Pg.217]

Other tests that can help determine the etiology include the high-dose dexamethasone suppression test, plasma ACTH test, metyrapone stimulation test, corticotropin-releasing hormone stimulation test or inferior petrosal sinus sampling. [Pg.217]

Table 3 Summary of data from studies of using the dexamethasone suppression test... Table 3 Summary of data from studies of using the dexamethasone suppression test...
Goenjian AK, Yehuda R, Pynoos RS, Steinberg AM, Tashjian M, Yang RK, Najarian LM, Fairbanks LA (1996) Basal cortisol, dexamethasone suppression of cortisol and MHPG in adolescents after the 1988 earthquake in Armenia. Am J Psychiatry 153 929-934 Gormley GJ, Lowy MT, Reder AT, Hospelhorn VD, Antel JP, Meltzer HY (1985) Glucocorticoid receptors in depression relationship to the dexamethasone suppression test. Am J Psychiatry 142 1278-1284... [Pg.399]

Grossman R, Yehuda R, New A, Schmeidler J, Silverman J, Mitropoulous V, Sta Maria N, Bgolier J, Siever L (2003) Dexamethasone suppression test findings in subjects with personality disorders associations with posttraumatic stress disorder and major depression. Am J Psychiatry 160 1291-1298... [Pg.399]

Kosten TR, Wahby V, Giller E, Mason J (1990) The dexamethasone suppression test and thyrotropin-releasing hormone stimulation test in posttraumatic stress disorder. Biol Psychiatry 28 657-664... [Pg.400]

Krishucm KRR, Rayasam K, Reed D, Smith M, ChapeU P, Saunders WB, Ritchie JC, Carroll BJ, Nemeroff CB (1993) The corticotropin releasing factor stimulation test in patients with major depression relationship to dexamethasone suppression test results. Depression 1 133-136... [Pg.400]

Newport DJ, Heim C, Bonsall R, Miller AH, Nemeroff CB (2004) Pituitary-adrenal responses to standard and low-dose dexamethasone suppression tests in adult survivors of child abuse. Biol Psychiatry 55 10-20... [Pg.401]

Weller, E.B., Weller, R.A., Fristad, M.A., and Bowes, J.M. (1990) Dexamethasone suppression test and depressive symptoms in bereaved children a preliminary report. / Neuropsychiatry Clin Neurosci 2 418-421. [Pg.123]

American Psychiatric Association (1987) The dexamethasone suppression test an overview of its current status in psychiatry. The APA Task Force on Laboratory Tests in Psychiatry. Am J Psychiatry 144 1253-1262. [Pg.133]

Carroll, B.J. (1982) The dexamethasone suppression test for melancholia. Br J Psychiatry 140 292-304. [Pg.133]

DST, dexamethasone suppression test HPA, hypothalamic—pituitary-adrenal. [Pg.585]

In the early 1980s, when the dexamethasone suppression test was in... [Pg.279]

Many centers have reported specific abnormalities on measures of hypo-thalamic-pituitary-adrenal axis activity in patients with psychotic depression. Patients with psychotic major depression (PMD) are among those with the highest rates of nonsuppression on the dexamethasone suppression test, and many of them have markedly elevated posttest levels (Carroll et al. 1976c, 1980 Coryell et al. 1982). Significant differences have been observed in 24-hour measures of urinary free cortisol between patients with psychotic and those with nonpsychotic major depression (NPMD) (R. F. Anton 1987). [Pg.305]

Arana GW, Baldessarini RJ, Ornsteen M The dexamethasone suppression test for diagnosis and prognosis in psychiatry. Arch Gen Psychiatry 42 1193-1204, 1985 Arana GW, Santos AB, Laraia EA Dexamethasone for the treatment of depression a randomized, placebo-controlled, double-blind trial. Am J Psychiatry 152 265-267, 1995... [Pg.587]

Catapano F, Monteleone P, Maj M, et al Dexamethasone suppression test and response to serotonergic drugs in OCD. European Psychiatry 6 273-274, 1991... [Pg.610]

Coryell W, Gaffney G, Burkhardt PE The dexamethasone suppression test and familial subtypes of depression a naturalistic replication. Biol Psychiatry 17 33-40, 1982... [Pg.616]

Holsboer E, Barden N Antidepressants and hypothalamic-pituitary-adrenocortical regulation. Endocr Rev 17(2 187-205, 1996 Holsboer f, liebl R, Hofschuster E Repeated dexamethasone suppression test during depressive illness normalization of test result compared with chnical improvement. J Affect Disord 4 93-101, 1982... [Pg.660]

Nemeroff CB, Evans DL Correlation between the dexamethasone suppression test in depressed patients and clinical response. Am J Psychiatry 141 247-249, 1984... [Pg.707]

Riemann D, Hohagen F, Bahro M, et al Cholinergic neurotransmission, REM sleep and depression. J Psychosom Res 38 [suppl l) 15-25, 1994 Rihmer Z, Arato M, Szadoczky E, et al The dexamethasone suppression test in psychotic versus nonpsychotic endogenous depression. Br J Psychiatry 145 508-511, 1984... [Pg.733]

Rudolph R, Entsuah R, Derivan A Early clinical response in depression to venlafaxine hydrochloride [abstract). Biol Psychiatry 29 6308, 1991 Rudorfer MV, Hau HG, Clayton PJ Dexamethasone suppression test in primary depression significance of family history and psychosis. Biol Psychiatry 17 41-48, 1982... [Pg.736]

Thus, these markers are most likely to be positive in psychotic depressions and least likely to be positive in atypical MDD, with melancholia falling between these two groups. A meta-analysis of reports on dexamethasone suppression tests found that nonsuppression was found in substantially more patients with psychotic versus nonpsychotic depression (64% versus 41 %) and in only 12% of outpatients with nonmelancholic major depression ( 10). The fact that these tests are most often positive in psychotic MDD is also consistent with the observation that they predict a low placebo response. [Pg.103]


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