Sugar coating

Control of relative humidity is needed to maintain the strength, pHabiUty, and moisture regain of hygroscopic materials such as textiles and paper. Humidity control may also be required in some appHcations to reduce the effect of static electricity. Temperature and/or relative humidity may also have to be controlled in order to regulate the rate of chemical or biochemical reactions, such as the drying of varnishes, the appHcation of sugar coatings, the preparation of synthetic fibers and other chemical compounds, or the fermentation of yeast. 

Sugar coating is time-consuming, requires skilled operators, and increases the tablet weight, sometimes to twice that of the uncoated core. 

Erodings of Slow-Releasing Core Tablets. The sustained-dose portion of a dmg is granulated with hydrophobic materials such as waxes, fatty acids, or fatty alcohols and compressed into a core. The initial dose is added to the core by a modified sugar coating process or by compression coating. Thus, a tablet within a tablet is created. The core erodes slowly to release the active ingredient. 

Formulation(s) sachet 60 mg sugar coated tabl. 60 mg syrup 0.6 %... 

The impetus for the registration process is that by requiring registration at the start of a trial, the public will know the number of trials and their key milestones and end points. Unpublished trials would raise a potential flag to physicians. In addition, by knowing commitment to key milestones and end points up front, there is less chance of sugar coating results. 

Stabilizer, viscosity-imparting agent, adhesive, binder, plasticizer, sugar coating agent... 

Baugh and co-workers exposed solutions of phenylbutazone to the light of a projector lamp in the presence of typical dyes used to colour sugar-coated tablets. Erythrosine sodium photosensitized decomposition of the drug via, it was suggested, singlet oxygen [134]. 

Sugar coated solid particles (environmental friendly) 29. Capture the liquids in supercritically dried polyvinylalcohol (Disperse slowly because the outer layer is hard to dissolve)... 

Of course, many natural materials are more difficult to reproduce in the laboratory than the sugar coating on corn kernels. One that still eludes materials scientists comes from bacteria that possess a magnetic sense. Just as many living creatures have a visual... 

In the mid-70s, it was a generally expressed opinion that there could be as many as 100 formulation factors that might affect bioavailability or bioequivalence. In fact, most of the documented problems centered around the use of the hydrophobic magnesium stearate as a lubricant or use of a hydrophobic shellac subcoat in the production of sugar-coated... 

The flow-through cell is applicable not only for the determination of the dissolution rate of tablets and sugar-coated tablets, but has also been applied to suppositories, soft-gelatin capsules, semisolids, powders, granules, and implants. A small volume cell containing the sample solution is subjected to a continuous stream of dissolution media. The dissolution... 

What can you infer from the two percentages Is the gum sugar-coated or are the sweeteners and flavorings mixed throughout ... 

The traditional tablet coating is a sugar coat applied in stages. First the tablet surface is sealed... 

Bes L, Angot S, Limer A, Haddleton DM. Sugar-coated amphiphilic block copolymer micelles from living radical polymerization recognition by immobilized lectins. Macromolecules 2003 36 2493-2499. 

Sugar-coated products have been marketed that contain KCl in a wax matrix (Slow-K and Kaon-Ct) and are purportedly slow- and controlled-release preparations. Available evidence indicates that these slow-release forms of KCl are occasionally capable of causing local tissue damage and therefore prol5ably should be used with caution for K+ supplementation. Solutions of potassium gluconate, like the tablets, also have been associated with intestinal ulceration. Microencapsulated KCl preparations Micro-K, K-Dur) that are neither enteric coated nor contained within a wax matrix appear to be superior to the wax matrix formulation. 

In contrast, oral administration of a willow bark extract showed a low bioavailability of salicin (98). After ingestion of commercial sugar-coated tablets containing willow bark extract corresponding to a total amount of 54.9mg (0.192mmol) salicin, the serum of 12 volunteers showed a peak concentration of only 0.13 pg/mL salicylic acid this is only 5% of the serum... 

Nakabayashi, K.,Shimamoto,T., and Mima,H. (1980), Stability of packaged solid dosage forms. II. Shelf-life prediction for packaged sugar-coated tablets liable to moisture and heat damage, Pharm. Chem. Bull., 28,1099-1106. 

Sugar Coating - Deposition of coating material onto the substrate from aqueous solution/suspension of coatings, based predominately upon sucrose as a raw material. 

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