Stomach Intestine

Pharmacology. Lycorine was first examined by Morishima wl found it relatively non-toxic to mammals. Given per os or subcutaneous, to the dog or cat, it causes, in small doses, salivation and in large dos vomiting and diarrhoea. It has no special effect on the blood pressure death seems to be due to a generalised collapse. Post mortem —hyper m and ecchymoses in the stomach, intestine, pulmonary pleura and end... 

P2Y14 Placenta, adipose tissue, stomach, intestine, discrete brain regions UDP glucose = UDP-galactose Gq/Gu... 

The complex polymers in feedstuffs are broken down to the constituent building blocks by a sequential process. Hydrolysis of the polymers is initiated in the lumen of the GIT by enzymes and other secretions produced by the pancreas, stomach, intestine, liver and gall bladder, and other GIT tissues, and completed by another suite of enzymes associated with the brush border membrane (BBM) or intracellular organelles. Anti-nutrient phytochemicals can decrease the hydrolysis of feedstuffs, and thereby reduce nutrient availability, either by increasing the inherent resistance of the polymers to hydrolysis or by decreasing the activities or amounts of enzymes and other secretions produced by the GIT. 

In additon to the central role of endocannabinoids in the regulation of feeding behaviour, a peripheral role has also been described. Gomez and coworkers [360] reported that food deprivation produced a 7-fold reduction in (1) levels in the small intestine of rats, but not in the brain or stomach. Intestinal (1) levels returned to normal when feeding resumed. The authors also showed that peripheral, but not central administration of (382) reduced food intake. The endocannabinoid system has also been reported to regulate peripheral lipogenesis [361]. 

Haber was mortified and shaken by Nernst s dressing down. Afterward, he suffered from stomach, intestinal, and skin problems, and Clara worried about his health. Years later at a large conference, he and Nernst shared a rostrum but pretended not to notice each other. 

Clinical trials of some of the more potent tertiary amines revealed these to exhibit marked psychotomimetic activity.11 Much subsequent work thus dealt with the quaternary salts which do not reach the central nervous system. Many of the uses of anticholinergic drugs involve "topical" application (e. g., interior of the stomach, intestine or bronchi) ... 

C]taurine-labeled MWNTs were administered to mice by three different exposure routes (intravenous injection, gavage, and intratracheal instillation) and their biodistribution was monitored [134], After intravenous injection, [14C]taurine-labeled MWNTs accumulated in the liver, heart, and lung after gavage administration, [14C]taurine-labeled MWNTs was only detectable in the stomach, intestine, and feces. No [14C]taurine-labeled MWNTs were detected in the blood. Finally, [14C] taurine-labeled MWNTs were partly cleared from the lungs after intratracheal instillation. Since various cell and tissue types have demonstrated a high affinity for uptake of taurine, it should be noted that the label used in this investigation may have influenced the biodistribution of the MWNTs tested [101]. 

Muscles (heart, etc.) Stomach/intestine Liver Kidney (bowel) Reproductive organs Glands Brain (Chapter 9) Sense organs Digestion, fluid circulation, motion, mechanical work Major zones of digestion Major zone of synthesis Major external rejection ion/water balance Reproduction Chemical controls Electrical control Environmental detectors... 

No observed effects at 682 mg/kg diet (and lower), equivalent to 104-109 mg Zn/kg BW daily. At 6820 mg Zn/kg ration, however, adverse effects were documented on survival, growth, food and water intake, and blood chemistry lesions noted in pancreas, stomach, intestine, spleen, and kidney. 

We do not know how mirex directly affects the health of people. However, animal studies have shown that eating mirex can cause harmful effects on the stomach, intestines, liver, and kidneys. Eating mirex can also cause harmful effects on the eyes, thyroid, nervous system, and reproductive system. Since these effects occur in animals, they may also occur in people. 

Rohypnol can also act directly on other parts of the body (such as the stomach, intestines, bladder, arteries) to produce gastrointestinal disturbances, reduced blood pressure, and urinary retention. 

What we commonly call movement depends on mnscle cells. There are several types of muscle in the hnman body heart mnscle striated skeletal muscle, which includes the large muscles of the body and smooth mnscle of the stomach, intestines, arteries and veins, and nterns. There is a fnndamental difference between striated and smooth muscle. You can control the former bnt not the latter. Yon can pretty mnch will what yon do with yonr arms and legs, for example. The activities of your stomach, veins and arteries, and intestines are pretty mnch beyond yonr ability to control by force of will. Heart is an exception heart mnscle is basically a striated muscle but we are at a loss to willfully control the rate or force of its contractions. 

The site of absorption is mainly localised in mouth (for buccal administration), stomach, intestines or colon. 

N.A. Carduus benedita L. Lignins, sesquiterpene lactones (cnicin), volatile oil, poly acetylenes.98 99 Stimulate the secretions of the stomach, intestines, gallbladder. 

Pao Jiang is bitter and warm, enters the Spleen and Liver meridians and also enters the blood level. Like Ai Ye, it can warm the interior, stop bleeding and alleviate pain, but its function focuses on the Middle-Jiao. It is especially effective for treating bleeding due to Spleen-Yang and Qi deficiency failing to control the blood. Such bleeding may be located in the stomach, intestines and uterus. 

Zao Xi Tu is warm and astringent, and enters the Spleen and Stomach meridians. It warms the interior and stops bleeding in both the Middle- and Lower-Jiao, such as bleeding from the stomach, intestines and uterus. Moreover, it binds up the intestines and stops diarrhea. It is more suitable for conditions of Spleen-Yang deficiency, such as chronic colitis, which manifests as abdominal pain and cramp, diarrhea, intestinal hemorrhage, cold hands and feet, and a pale complexion. 

The authors pointed out that such a metabolic pathway may complicate the results of biosynthetic studies in certain species, as it would provide a route for the oxidation of L-fucose and its eventual provision of carbon atoms to other sugars. This metabolic route does not occur in rats, but it is known215 that humans can oxidize L-[l-,4C]fucose to carbon dioxide. Only pig liver and kidney were found to contain appreciable levels of the major enzymes needed in this pathway, whereas heart, stomach, intestine, submaxillary gland, lung, and brain were deficient in or devoid of them. 

Levamisole (Fig. 6.9) is a tetrahydro-imidathiazole that is widely used and is particularly effective for the control of stomach, intestinal and lung worm in... 

Very potent mutagen.4 In experimental animals, causes cancer of the stomach, intestine, skin, and lung, and at the site of injection.5 Reasonably anticipated to be a human carcinogen.6 7 LD50 (oral, rat) 400 mg/kg.8... 

Diet Stomach Intestine Cecum Stomach Intestine Cecum... 

The body tissues are generally submitted to a toxicological laboratory in sufficient quantities hence these specimens are better suited for quantitative analysis. The detection and determination of the unchanged insecticide in the stomach, intestine, liver, kidney, spleen, lungs, brain, and in other tissues and body fluids are useful indicators of direct insecticide action. 

Nausea, vomiting, diarrhoea, damage to tissue including nerves, stomach, intestines and skin... 

Gastrointestinal Peptides (Peptides of the Stomach, Intestine, and Pancreas) 125... 

DNOC and/or its metabolites have been measured in various body fluids and tissues such as blood, urine, liver, stomach, intestine, brain, and heart of humans (Harvey et al. 1951 King and Harvey 1953b Sovljanski et al. 1971) and animals (King and Harvey 1953a Lighterage et al. 1982 Treat and De Louver 1967). Detection of DNOC in body fluids or tissues, therefore, can serve as a qualitative indication that exposure to DNOC occurred. 

---